A mutation is identified in a tumor sequencing study. Which of the following pieces of evidence would most strongly suggest that the mutation is a passenger mutation?
a. The same gene is mutated in many other individuals with the same kind of cancer.
b. The mutation impacts the function of a known tumor suppressor gene.
c. The mutation is a silent point mutation in a protein-coding sequence.
d. The gene carrying the mutation is known to participate in the cell cycle.

Answers

Answer 1

Answer:

The mutation is a silent point mutation in a protein-coding sequence.

Explanation:

A mutation is a change or alteration in DNI sequences that introduce new variants. Many of these are eliminated, but some of them might succeed and be incorporated into each individual. Mutations can be damaging or beneficial.

There are two types of mutations in cancerous cells:

· Driver mutations, which refer to genetic changes that provide malign cells an adaptative advantage. These mutations drive the cells to tumoral evolution.

· Passenger mutations, also known as neutral mutations, refer to those that do not provide any advantage nor disadvantage to the cancerous cell. These mutations can be between DNI segments where the driver mutations are. Some of these passenger mutations might become driver mutations with time.    


Related Questions

When a neuron is stimulated and sodium channels open, the process of has begun. Structures of the nervous system surrounding, but not part of the central nervous system are part of the . Two consecutive neurons communicate at a , where they physically come together. are a group of natural chemicals that reduce the perception of pain. Supporting cells of the nervous system are collectively called . When potassium channels have been open long enough to go below resting membrane potential, has occurred.

Answers

Answer:

- When a neuron is stimulated and sodium channels open, the process of depolarization has begun.  

- Structures of the nervous system surrounding, but not part of the central nervous system are part of the peripheral nervous system

- Two consecutive neurons communicate at a synapse, where they physically come together.  

- Endorphins are a group of natural chemicals that reduce the perception of pain.  

- Supporting cells of the nervous system are collectively called neuroglia

- When potassium channels have been open long enough to go below resting membrane potential, hyperpolarization has occurred.

Explanation:

Neurons undergo depolarization in response to diverse stimuli (e.g., heat, light, electrical, chemical, etc). The depolarization occurs when sodium (Na+) ions pass through specific channels  (i.e., open voltage-gated Na+ channels) into a neuron, which causes an increase in the positivity of membrane potential. On the other hand, hyperpolarization occurs when potassium (K+) channels remain open and Na+ channels reset, thereby producing an increase in negativity of membrane potential. The peripheral nervous system (PNS) is composed of the cranial nerves, spinal nerves, peripheral nerves, and neuromuscular junctions, which connect the Central nervous system (CNS) to the organs, limbs, and skin. Endorphins (e.g., serotonin) are polypeptides secreted by the pituitary gland and CNS to relieve stress and pain. Neuroglia refers to a class of neural cells that have ectodermal (e.g., astroglia, peripheral glial cells) or mesodermal (e.g., microglia) origins. Neuroglia cells are involved in diverse roles, including, among others, the formation of the blood-brain barrier, homeostatic support, provision of nutrients for neurons, structural support to nerve cells, etc.

Which phrase best describes a savana biome

Answers

Answer:

A biome that is dry most of the time long tall dried out grass. The savanna is home to many large land mammals, including elephants, giraffes, zebras, rhinoceroses, buffalo, lions, leopards, and cheetahs. Other animals include baboons, crocodiles, antelopes, meerkats, ants, termites, kangaroos, ostriches, and snakes.

Explanation:

Hope this helps ! <33

A savanna biome is a biome that’s practically like a dessert but it has grass and trees so it’s a dried out biome

why is climate change a serious threat to the least developed countries practicing agriculture as their main occupation mountain region island and low lying countries​

Answers

Answer:

Increase in sea level on the low lying countries which leads to degradation and salinification thereby making the soil non-arable. Meanwhile on the mountain regions, melting glaciers caused by rain falling on snow leads to mountain floods, avalanches and extreme rockslide and thereby disrupting agricultural produce and wildlife.

Explanation:

why are electrons in an atom involved in bonding

Answers

Answer:

The valence electrons have a role in the bonding of two atoms. The nuclei of each atom are drawn together by their attraction to the valence electrons of the other atom. As the atoms are drawn together by their attractions, electrons from each atom are drawn to the nuclei of both atoms, where they are "shared."

OAmalOHopeO

The following statement is incorrect as stated "Pesticides create pesticide resistance in mosquitoes." Rewrite this sentence so that it is a more accurate statement of what actually occurs when pesticides are used. Why is this concept important to know in trying to control outbreaks of mosquito transmitted diseases such as eastern equine encephalitis (also known as Triple E)?

Answers

Answer:

Mosquitoes usually become resistant to pyrethroids through the mutation of a sodium channel gene that controls the movement of ions across cell membranes. Mutations in a single gene are enough to make mosquitoes almost completely resistant to the level of pyrethroids used in insecticides.

3. A bacterial isolate from a urine specimen was grown in culture, Gram stained, and then tested for its ability to ferment sugars and hydrolyze various subtrates. What approach to bacterial identification is this an example of

Answers

Answer:

Phenotypic approach for bacterial identification

Explanation:

Bacterial identification can be done by conventional methods, which are based on phenotypical characteristics. These methods are much affordable and reasonable.

Phenotypical identification is based on bacteria´s observable characteristics, such as their morphology, development, and biochemical/metabolic properties.

It is important to consider that these methods do not provide absolute certainty. They can only indicate the genera or species to which the bacteria under study may belong.

Some primary evidence is usually used for fast bacteria identification:

Gram staining, morphology, growth at different media or different incubation atmospheres, glucose fermentation, spores production, motion, aerobiosis/anaerobiosis, among others.  

Knowing that the bacteria in the exposed example was isolated and grown in culture, then Gram-stained and tested for biochemical reaction, we can assume that the approach for its identification is phenotypic.  

One of the important feature of
tropical region is

Answers

Answer:

A tropical climate is marked by consistently warm temperatures and frequent rainfall, resulting in abundant, diverse vegetation. The seasons are marked primarily by precipitation variation rather than temperature changes, as the latter in the area are minimal.

Explanation:

hope you will be hepled!

Which of the following is correct?
Select one:
a. Industry and agriculture both overuse surface water resources.
b. Industry and agriculture both overuse groundwater resources.
c. Industry overuses surface water and agriculture overuses
groundwater.
O d. Industry overuses groundwater and agriculture overuses
surface water

Answers

Hey i think the answer is C :)

Water is a source that is used for various purposes. The industry overuses the surface water, whereas agriculture overuses the groundwater leading to water scarcity. Thus, option C is correct.

What is water scarcity?

Water scarcity is the unavailability of water or can be said as a shortage of water through the regular supplies due to the overuse and excess waste of these resources.

The lack of sufficient amount of water that has been said to be not equal to the demand is a major issue that affects every organism globally. It can lead to economic decline as there will be drought.

Water is used in various fields including the industries for machines and other works, and also in agriculture fields to grow plants and crops. The industry uses the water present on the surfaces like lakes, and rivers, while crops need the water from the wells.

Therefore, option C. the industry and agriculture overuse water.

Learn more about water scarcity here:

https://brainly.com/question/19920929

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All claims in science should be supported by biology

Answers

Answer:

yes

Explanation:

Because science &biology have a connection

Drag each of the following labels into the appropriate box to identify which motor division of the peripheral nervous system is identified by the given function.an be excitatory or inhibitory on the target organ Principally involved with movement of materials through the body Skeletal muscle activation Intestinal smooth muscle activation Voluntary Sweat gland activation Lacrimal gland activation Principally involved with movement "of" the body principally invvedPiloerector muscle Involuntary activation Somatic Autonomic

Answers

Answer:

Somatic: Skeletal muscle activation VoluntaryPrincipally involved with movement "of" the body.Autonomic: Can be excitatory or inhibitory on the target organ. Principally involved with the movement of materials through the body. Intestinal smooth muscle activation. Sweat gland activation Lacrimal gland activation Piloerector muscle Involuntary activation.

Explanation:

We can divide the nervous system into the central nervous system, which consists of the brain and spinal cord, and the peripheral nervous system, which consists of all the nerves that are throughout the body carrying information from and to the central nervous system.

We divide the peripheral nervous system into the somatic nervous system and the autonomic nervous system.

The somatic nervous system is the conscious one, that is to say, that we know and control what it does. It is voluntary. It has motor and sensory neurons that carry information to and from the central nervous system. The somatic nervous system is the one that makes us move our muscles to do an action.

The autonomic nervous system is involuntary. In other words, we can not control it consciously. It is the one that controls glands, organs, and smooth muscle, like the one that surrounds the digestive tract to move the food. As we can not consciously control it, this system can work exiting or inhibiting an organ depending on the situation.

The  peripheral nervous system is simply divided into 2 types, which are the somatic nervous system and the autonomic nervous system.

SOMATIC

Voluntary principally involved with movement "of" body skeletal muscles activation

AUTONOMIC

Involuntary lacrimal gland activation intestinal smooth muscle activation principally involved with movement "through" body sweat gland activation arrector pili activation can be excitatory or inhibitory on target organ

The peripheral nervous system (PNS) is the simply known as the division of the nervous system that has all the nerves that is found outside of the central nervous system (CNS).

Its primary role is to connect the central nervous system to various organs such as the limbs, and skin.  simply divided into 2 types, which are the somatic nervous system and the autonomic nervous system.

Learn more from

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how do humans impact the biodiversity of ecosystems

Answers

Answer:

Humans affect biodiversity by their population numbers, use of land, and their lifestyles, causing damage to habitats for species. Through proper education, and by demanding that governments make decisions to preserve biodiversity, the human population will be able to sustain life on earth longer.

Explanation:

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Human population levels, land usage, and lifestyles all have an impact on biodiversity, causing damage to species' habitats. The human population will be able to maintain life on Earth for longer if adequate knowledge is provided and governments are forced to make decisions that protect biodiversity.

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[tex]\texttt{HOPE IT HELPS}[/tex]

[tex]\texttt{HAVE A GREAT DAY!!}[/tex]

what is defferenciated cell and and undeferenciated cell.with example​

Answers

Answer:

Differentiated cells refer to the specialized cells in multicellular organisms modified to carry out a particular function, such as transporting a certain substance or executing a specific task, while undifferentiated cells refer to the stem cells capable of giving rise to indefinitely more cells of the same type,.

example of differentiated cell=zygote to embryo then a comlex foetusexample of undifferentiated cell= embryonic stem cell.

hope it helpsstay safe healthy and happy.

Defined forestry and its important in nepal?​

Answers

Explanation:

In a mountain- ous country such as Nepal, forests are important for the protection of water catchments, the conservation of soil and the maintenance of biodiversity, as well as for their contributions to sustainable rural livelihoods and the maintenance of the environment.

Answer:

forest is defined as a large area that has many trees and other plants, or a dense area that is like a forest.

its important in nepal are:

1.for the protection of water catchments,

2.for the conservation of soil and

3.for the maintenance of biodiversity,

4.. for their contributions to sustainable rural livelihoods

5.the maintenance of the environment.

6.it increase the natural beauty of nepal

हरियो वन नेपालको धन

जय नेपाल

Normally, this region is imprinted in the sperm, but not the egg. This means that the DNA on the ____________ copy of the chromosome will be methylated at the imprinting center, while the DNA on the ____________copy of the chromosome will not be methylated in this region.

Answers

Answer: The DNA on the paternal copy of the chromosome will be methylated at the imprinting center, while the DNA on the maternal copy of the chromosome will not be methylated in this region.

Explanation:

Chromosomes are DNA structures associated with proteins such as histones. They are found in the nucleus of cells and contain genetic information for the development and functioning of an organism. Human beings are diploid, meaning that they possess two copies of each of the 23 chromosomes (a total of 46).

Gametes, which are sex cells such as the sperm (produced by the male) and the egg (produced by the female) that are haploid. This means that they possess only one chromosome of each pair. During fertilization, a male gamete fuses with a female gamete to generate a zygote, which will give rise to a new human being. This new individual will possess half of the genetic material from its father and half from its mother. Thus having a total of 46 chromosomes, 23 from each parent.

Genetic imprinting modulates gene expression by chemical modification of DNA and/or modification of chromatin structure. Often, genetic imprinting causes a gene to be expressed only on the chromosome inherited from one of the parents. One example of imprinting is DNA methylation, which is a process by which methyl groups are added to DNA. Methylation modifies DNA function when found in the promoter gene, repressing gene transcription. This means that a methylated gene will not be expressed, that is, it will not produce a protein encoded by that gene. So, if a region of DNA is imprinted in the sperm cell, the paternal chromosome inherited from this sperm will be methylated in the genes of the offspring. And the offspring will only express the maternal copy inherited, which will not be methylated.

2 True or False. A projectleie an object that once set in motion continues in motion by its own martia O True False ​

Answers

Answer:

The answer is true.Explanation:PARTICLES MOVING ALONG THE PATH POSSES A TWO DIMENSIONAL MOTION

MARK ME AS BRAINIST PLZ

The brain generally stores new information in its own different and unique netowrk but retrieves information by chunking it with information in netowkrs that contain similar characteristics or associations.

a. True
b. False

Answers

A would be the correct answer I believe

How will you isolate DNA from a pure fungal culture

Answers

Answer:

Explanation:

There are several ways of isolating DNA from a pure fungal culture but you can use the CTAB method.

In this method, genomic DNA can be extracted.

First of all, the cell walls of fungal mycelia can first be broken down by grinding it using glass rods or you can use or liquid nitrogen. Place it in a plate. You can now CTAB extraction buffer , then incubate at 65°C, then let it undergo purification with phenol:chloroform:isoamyl alcohol 25: 24: 1 and carry out precipitation with isopropanol . Then the DNA can be extracted and then dissolved in 50 μl of pure water.

The suprachiasmatic nuclei enable the nervous system to respond to daily light/dark alterations through their stimulation of

Answers

Answer:

The suprachiasmatic nuclei enable the nervous system to respond to daily light/dark alterations through their stimulation of melatonin.

Explanation:

Melatonin is a hormone produced naturally by the body. Its function is to regulate the body's circadian cycle. This hormone is stimulated and begins to act by changing between a light environment and a dark environment. This stimulation interacts with the suprachiasmatic nuclei making the nervous system understand this change and luminosity of the environment and respond to the action of melatonin.

I am stuck please help !!!!!!

Answers

I’m not sure about your experiment can you explain?

What dose that mean please help

Answers

Explanation:

A = pi * r²

This is used to measure the area of a circle.

The value of pi is 22/7 or 3.14 and r is the radius of the circle.

Hope it helps :)

That’s the area of an entire circle

different evolution theory of living organism​

Answers

Answer:

(I) Lamarckism or Theory of Inheritance of Acquired characters.

This theory is based on the comparison between the contemporary species of Jean Baptiste de Lamarck's time to fossil records.

(II) Darwinism or Theory of Natural Selection.

Charles Darwin made an extensive study of nature for over 20 years, especially in 1831-1836 when he went on a voyage on the famous ship “H.M.S. Beagle” and explored South America, the Galapagos Islands and other islands.

(III) Mutation theory of De Vries.

The mutation theory of evolution was proposed by a Dutch botanist, Hugo de Vries (1848-1935 A.D.) in 1901 A.D. in his book entitled “Species and Varieties, Their Origin by Mutation”. He worked on evening primrose (Oenothera lamarckiana).

(IV) Neo-Darwinism or Modern concept or Synthetic theory of evolution.

The detailed studies of Lamarckism, Darwinism and Mutation theory of evolution showed that no single theory is fully satisfactory. Neo-Darwinism is a modified version of theory of Natural Selection and is a sort of reconciliation between Darwin’s and de Vries theories.

Explain why it is not advisable for two sickle cell carriers to marry.​

Answers

Answer:

it results in pleiotropic effect and caused death of an offspring.

plz help
and explain why?

Answers

Answer:

steel plate

Explanation:

steel plate have lustre because steel is coated with zinc.

Hope it is helpful....

All of the following factors contribute to the differences in complex trait risk predictions between different laboratories, EXCEPT ____________. differing methods of combining risk from multiple genetic variants selection of different genetic variants for risk determination different assessments of environmental factors genotyping of different variants

Answers

Answer:

different assessments of environmental factors

Explanation:

In humans, for predicting the future phenotype of any individual, the PSR is used.

A trait may be defined as the state of a character that is a distinct variation of the phenotypic characteristic of any organism.

The following factors contributes to the differences in the complex trait risk predictions in the different laboratories :

-- differing methods of the combining risk from the multiple genetic variants.

-- genotyping of the different variants.

-- selection of the different genetic variants for such risk determination.

Thus the factor which does not contribute is :

"different assessments of the environmental factors."

choose the letter of the correct answer 1. Which one of the following is NOT an organic compound? a. Methane b. Carbon dioxide d. Lactic acid C. Oil​

Answers

Answer:

B

Explanation:

What is the common difference for this arithmetic sequence?
54, 50, 46, 42, 38, ...
A. 4
B. 54
C. 34
O D. -4

Answers

Answer:

D) -4

This is because each term is four less than the previous term.

Explanation:

Answer:

D

Explanation:

because it is going down -4 every time

Afferont neurons
a.transmit sensory input to the CNS
b.are multipolar neurons
c.have many dendrites and a single long axon
d.are found only within the brain and spinal cord

Answers

Answer:

a.transmit sensory input to the CNS

Explanation:

Afferent neurons will take input from your muscles, skin etc. and send it to your CNS (usually via spinal nerves).

based on the 1:2:1 proportions of carbon, hydrogen and oxygen, it can be determined that a glucose molecule is a

Answers

Answer:

Carbohydrate (monosaccharide)

Explanation:

Carbohydrates are one of the four biological molecules in nature. Carbohydrates are structurally composed of carbon, hydrogen and oxygen elements. However, these elements (C,H,O) are present in each carbohydrate in the ratio 1:2:1 respectively.

As stated in this question, glucose is an organic molecule made up of carbon, hydrogen and oxygen in the 1:2:1 proportion, hence, it is a CARBOHYDRATE. Since glucose possess one sugar component, it is classified as a MONOSACCHARIDE with a chemical formula C6H12O6.

How are meiosis and mitosis similar?



A.They both produce diploids.

B.They happen at the same time.

C.They both produce sex cells.

D.They both produce new cells.

Answers

Answer:

D.They both produce new cells.

Explanation:

Meiosis and mitosis are both processes of cell division; however, they have many differences. Meiosis occurs in sex cells and produces haploids that can be fertilized. Mitosis occurs in body cells and produces diploids that replace old or damaged cells. Still, both processes result in the creation of new cells.

Answer:

D) They both produce new cells!

Explanation:

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Which of the following statements depend on the absolute dating of events?

Answers

Answer:

The statement that depends on the absolute dating of events is this: The oldest Earth rocks are 3.9 billion years old. Absolute dating is the method of determining the specific date of an archaeological or paleontological artifact.

Answer:

It says that the oldest Earth rocks are 3.9 trillion years old, and they depend on the absolute adaptations of events. Absolute dating is the mechanism through which an archaeological or paleontological artifact determines a particular date.

120 million years ago, birds diverged from the related dinosaurs.3.9 billion years old is the oldest Earth rock.

Explanation:

Geologists must often know the material age they encounter. They use absolute data systems, sometimes referred to as numerical dates, to provide rocks with the actual date or date range for years to come. It differs from relative dates, which only time-consuming geologic events.

In contrast to the relative date, the absolute date represents a certain age or range which places occurrences among events without age being measured. The most absolute ages for rocks are reached by radiometric methods. Minerals are radioactive in rocks like geological watches.

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