Arrange the sequence of events involved with muscle contraction in the correct order. Begin with "Ca2+ binds to troponin . . ."
#1 A power stroke occurs. This is a process whereby ADP and Pi are released and the activated myosin head pivots sliding the thin filaments toward the center of the sarcomere.
#2 The cocked activated myosin head of the thick filament binds to the active site on thin filament, forming a cross bridge.
#3 A new ATP binds to the myosin head, weakening the bond between the myosin head and thin filament.
#4 Ca2+ binds to troponin on the thin (actin) filaments.
#5 Troponin-tropomyosin complex on thin filaments changes shape exposing active sites along the thin filaments. The active sites serve as sites for binding to myosin heads.
#6 ATP bound to the myosin head of the thick filament is hydrolyzed to ADP and phosphate (Pi).
#7 ADP and Pi remains bound to the myosin head and the energy released from the hydrolysis of ATP activates the myosin head forcing it into the "cocked" position
#8 Myosin head detachment occurs, breaking the crossbridge.
#9 Myosin hydrolyzes the new ATP bound and uses the energy released to "recock" the myosin head, preparing the myosin head to repeat cross bridge cycle.

Answers

Answer 1

The main sequence of events in muscle contraction can be summarized as follows:

1. Ca2+ binds to troponin, exposing active sites on the thin filaments.

2. Myosin binds to the active site, forming a crossbridge.

3. Power stroke occurs, resulting in sliding of the thin filaments.

4. Myosin detaches, and the cycle continues with ATP binding and recocking of the myosin head.

The correct sequence of events involved in muscle contraction is as follows:

1. Ca2+ binds to troponin on the thin (actin) filaments.

2. Troponin-tropomyosin complex on thin filaments changes shape, exposing active sites along the thin filaments.

3. The cocked activated myosin head of the thick filament binds to the active site on the thin filament, forming a crossbridge.

4. Power stroke occurs. This is a process whereby ADP and Pi are released, and the activated myosin head pivots, sliding the thin filaments toward the center of the sarcomere.

5. Myosin head detachment occurs, breaking the crossbridge.

6. A new ATP binds to the myosin head, weakening the bond between the myosin head and thin filament.

7. Myosin hydrolyzes the new ATP bound and uses the energy released to "recock" the myosin head, preparing it to repeat the crossbridge cycle.

It's important to note that this sequence repeats as long as there is sufficient Ca2+ and ATP available for muscle contraction to continue.

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Related Questions

Which carbon-to-hydrogen mass ratio is possible for another compound composed only of carbon and hydrogen? you may need to round your answer to three significant figures before evaluating your answer.

Answers

The carbon-to-hydrogen mass ratio for another compound composed only of carbon and hydrogen can vary. However, if we assume that the compound is hydrocarbon-based, the possible carbon-to-hydrogen mass ratios can be determined by considering the molecular formulas of different hydrocarbons.


1. Determine the molecular formula of the hydrocarbon compound. Let's assume it is CₓHᵧ, where x represents the number of carbon atoms and y represents the number of hydrogen atoms.

2. Calculate the molar mass of carbon (12.01 g/mol) and hydrogen (1.008 g/mol).

3. Calculate the total molar mass of the compound by multiplying the number of carbon atoms (x) by the molar mass of carbon and the number of hydrogen atoms (y) by the molar mass of hydrogen. The total molar mass is given by: (12.01 * x) + (1.008 * y) g/mol.

4. Calculate the carbon-to-hydrogen mass ratio by dividing the molar mass of carbon (12.01 * x) by the molar mass of hydrogen (1.008 * y): (12.01 * x) / (1.008 * y).

To round the answer to three significant figures, you would need to round the x and y values to three significant figures before calculating the ratio.

In summary, the carbon-to-hydrogen mass ratio for a compound composed only of carbon and hydrogen can vary depending on the molecular formula.

To calculate the ratio, determine the molar mass of carbon and hydrogen, calculate the total molar mass of the compound, and divide the molar mass of carbon by the molar mass of hydrogen. Remember to round your answer to three significant figures.

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To generate conventional transgenic mice, DNA will be injected into:
Group of answer choices
-embryonic stem (ES) cells
-fertilized mouse eggs
To determine success of homologous recombination of targeting vector in ES cells, Northern blotting will be utilized.
Group of answer choices
-Yes
-No
In the CRISPR/Cas9 system, guide RNA directs the enzyme to cut the DNA at a specific site in the genome.
Group of answer choices
-True
-False

Answers

To generate conventional transgenic mice, DNA will be injected into fertilized mouse eggs. The statement "To determine the success of homologous recombination of the targeting vector in ES cells, Northern blotting will be utilized" is True. The statement "In the CRISPR/Cas9 system, guide RNA directs the enzyme to cut the DNA at a specific site in the genome" is also True.

A transgenic animal is one that carries a foreign gene that has been transferred to it. Transgenic mice, for example, can be used to study gene function or the creation of human disease models. To generate transgenic mice, DNA is injected into the pronucleus of a fertilized mouse egg.

The egg is then implanted into a pseudopregnant foster mother's uterus, and the offspring is screened for the presence of the transgene. To determine the success of homologous recombination of the targeting vector in ES cells, Northern blotting will be utilized. True.

Homologous recombination (HR) is a genetic exchange between two identical or very similar nucleotide sequences. HR has been used in ES cells to generate a conditional knockout of a gene of interest. The CRISPR/Cas9 system uses guide RNA to direct the enzyme to cut the DNA at a specific site in the genome.

Guide RNA is one of the key components of the CRISPR-Cas9 system. Guide RNA directs Cas9 to the correct site in the genome so that it can make the necessary modifications or insertions or deletions.

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Which of the following is LEAST likely to be critical for maintaining tolerance to gut microbiota? a. B cell class switching to IgA b. Regulatory T cells c. Production of the cytokines IL-10 and TGF-beta d. T cell expression of inhibitory receptors e. Pyroptosis induced by NLRS

Answers

Pyroptosis induced by NLRS is LEAST likely to be critical for maintaining tolerance to gut microbiota. The answer is (E).

Pyroptosis is a form of programmed cell death that involves the rupture of a cell's plasma membrane, which leads to the release of inflammatory intracellular components. Pyroptosis is distinct from necrosis, apoptosis, and other forms of programmed cell death in terms of its cell morphology and mechanism.

Pyroptosis is mediated by caspase 1, caspase 4, caspase 5, caspase 11, or caspase 12 in mammalian cells.Tolerance to gut microbiota is maintained by the immune system in a variety of ways. Among the options given, Pyroptosis induced by NLRS is least likely to be critical for maintaining tolerance to gut microbiota. Therefore, the correct answer is option e. Pyroptosis induced by NLRS.

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These substances typically exert their effects through either causing the release of neurotransmitters or inhibiting the re-uptake of neurotransmitters, particularly epinephrine and norepinephrine.
a. Steroids
b. Selective estrogen receptor modulators
c. Stimulants
d. Peptide hormones

Answers

The substances that typically exert their effects through either causing the release of neurotransmitters or inhibiting the re-uptake of neurotransmitters, particularly epinephrine and norepinephrine are stimulants.

Neurotransmitters are the chemical messengers that transmit signals between neurons, glands, and muscles across the synaptic cleft. Neurotransmitters play a vital role in the function of the nervous system. Their effect can be either inhibitory or excitatory, which determines whether or not an action potential will occur in the postsynaptic neuron.

Epinephrine (also known as adrenaline) and norepinephrine are catecholamines that are synthesized from the amino acid tyrosine and are responsible for the "fight or flight" response of the sympathetic nervous system. Stimulants are substances that increase activity in the nervous system, leading to increased arousal and alertness. These substances typically exert their effects through either causing the release of neurotransmitters or inhibiting the re-uptake of neurotransmitters, particularly epinephrine and norepinephrine. Thus, the correct option is c. Stimulants.

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compare similarities and differernces of male and female
anatomy

Answers

The male and female anatomy have similarities and differences. The similarities between the two sexes are that they both have a nervous system, cardiovascular system, and respiratory system. Additionally, they both have a digestive system, urinary system, and lymphatic system.

Both sexes also have a skeletal system, a muscular system, and an endocrine system. The differences in male and female anatomy are apparent in the reproductive system. The female has a uterus, ovaries, and a vaginal canal, which are used for menstruation and childbirth.

Males, on the other hand, have testes, seminal vesicles, a vas deferens, and a prostate gland, which are used for producing and storing sperm. Another difference is the male's adam's apple and deeper voice, which are caused by a larger larynx. In conclusion, there are some similarities and differences between male and female anatomy, with the most significant differences being in the reproductive system.

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Hydrocephalus is a buildup of cerebrospinal fluid in the ventricles of the brain. Explain why this buildup is a serious problem, and propose a sign or symptom that would indicate cerebrospinal fluid buildup

Answers

Hydrocephalus is a medical condition where there is an excessive accumulation of cerebrospinal fluid in the brain's ventricles. The buildup of fluid is a serious problem because the increased pressure may cause brain damage, leading to cognitive and physical disabilities or even death.

A headache is a symptom of cerebrospinal fluid buildup. Cerebrospinal fluid helps to cushion the brain and spinal cord from injuries. In normal cases, it circulates in the brain and spinal cord to protect them from sudden movements and injuries. However, in hydrocephalus, the cerebrospinal fluid is unable to circulate correctly due to blockages or other reasons.

The excessive accumulation of cerebrospinal fluid leads to an enlarged head, visible in infants and younger children. In older children and adults, there may be a sudden onset of headaches, vomiting, nausea, blurred or double vision, difficulty walking, balance and coordination problems, poor coordination, and other cognitive problems, including memory loss and concentration problems.

Therefore, if one experiences a sudden headache or a headache that persists for a while, it may indicate cerebrospinal fluid buildup. It is a medical emergency, and you should seek medical attention promptly.

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Hydrocephalus is a serious condition that requires prompt treatment to avoid complications and mitigate its effects.

Hydrocephalus is a condition that occurs when there is a buildup of cerebrospinal fluid in the brain's ventricles. This buildup can cause a range of problems and can be serious if left untreated. One sign or symptom that may indicate cerebrospinal fluid buildup is a headache that worsens in intensity over time.Hydrocephalus can be caused by a range of factors, including a blockage in the ventricles, a decrease in cerebrospinal fluid absorption, or an overproduction of cerebrospinal fluid.

Regardless of the cause, the buildup of fluid in the brain can cause pressure to increase inside the skull, which can lead to a range of problems and complications.Among the most serious issues associated with hydrocephalus are brain damage, seizures, and loss of vision. As pressure increases in the brain, it can cause damage to the delicate tissues and structures inside, leading to cognitive problems, developmental delays, and other issues. Seizures are another potential complication of hydrocephalus, as the electrical activity in the brain may be disrupted due to the buildup of fluid.

Finally, the increased pressure in the brain can also lead to vision loss, particularly if it affects the optic nerves or other critical structures.In terms of identifying cerebrospinal fluid buildup, one of the most common signs is a headache that worsens over time. This is often accompanied by nausea, vomiting, and other symptoms of increased pressure inside the skull.

Other signs may include a change in vision, including double vision or loss of vision in one or both eyes. Finally, people with hydrocephalus may also experience difficulty with balance and coordination, as well as developmental delays or cognitive problems if the condition is present from birth.

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if Tertilization occurs, the corpus A. Produces estrogen. B. Produces progesterone. C. Produces inhibin D. All of the above E. Only two of the above. 493 points Breast milk production is stimulated by: A. FSH. B. Oxytocin. C.DHT. D. Relaxin. E. Prolactin. 50 3 points For which of the following STD's is there no cure? A. Syphilis. B. Gonorrhea. C. Trichomoniasis. D. Herpes Simplex 11 F.Chlamydia

Answers

If fertilization occurs, the corpus luteum produces progesterone, estrogen, and inhibin. The correct option is D. All of the above. In the female reproductive system, the corpus luteum is a gland that is formed in the ovary after ovulation.

Breast milk production is stimulated by the hormone prolactin. Therefore, the correct option is E. Prolactin. Breast milk production, also known as lactation, is stimulated by hormones. Prolactin is the primary hormone responsible for this process. Prolactin is generated by the anterior pituitary gland in response to an infant's suckling or suckling sounds.

There is no cure for Herpes Simplex 11. Therefore, the correct option is D. Herpes Simplex 11. Sexually transmitted diseases are caused by bacteria, viruses, or other pathogens that are spread via sexual contact. While some STDs can be cured with antibiotics or other medications, there are others for which there is no cure.

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Which of the following are functions of the skeletal system?
(select all that apply)
a) mineral storage
b) support for ears and nose
c) regulation of pH
d) hematopoiesis
e) protection of the brain and

Answers

The functions of the skeletal system are given below: a) Mineral storage) Hematopoiesis. e) Protection of the brain and other delicate organs.

1. The skeletal system is an organ system that gives shape, support, and movement to the body.

2. Bones act as a storage facility for minerals such as calcium and phosphorus.

4. Hematopoiesis: Bones contain bone marrow, which is where blood cells are made.

3. Protection of the brain and other delicate organs: The skeletal system protects vital organs such as the brain, heart, and lungs. The skull and rib cage, which are made of bone, protect the brain and lungs respectively.

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How is having a genetic predisposition to a disease related to contracting that disease?
Having a predisposition to a disease is unrelated to contracting that disease.
A predisposition makes a disease more likely, but it does not guarantee that the disease will be contracted.
A predisposition toward a disease means that the person will contract the disease.
Identifying a predisposition means that effective treatments can begin early, and the disease can be thoroughly avoided.

Answers

Having a genetic predisposition to a disease is related to contracting that disease because it means that an individual has an increased likelihood of developing the disease in question.

This means that they are at a higher risk of contracting the disease compared to individuals who do not have the genetic predisposition to that disease.
However, having a genetic predisposition does not guarantee that the individual will contract the disease. This is because there are often a variety of factors that can contribute to the development of a disease, including environmental factors, lifestyle choices, and other genetic factors.
Identifying a genetic predisposition to a disease can be beneficial in many ways. For one, it can help individuals take steps to reduce their risk of contracting the disease, such as making changes to their lifestyle or undergoing regular medical screenings. Additionally, it can help healthcare professionals provide targeted treatment and care to individuals who are at a higher risk of developing the disease.
In conclusion, while having a genetic predisposition to a disease is related to contracting that disease, it is not a guarantee. Identifying a genetic predisposition can be useful in many ways, including helping individuals reduce their risk of contracting the disease and helping healthcare professionals provide targeted care and treatment.

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This type of membrane lines true cavities which are not connected to the outside of the body
A. Synovial membranes
B. Mucous membranes
C. Dialysis membranes
D. Cutaneous membranes
E. Serous Membranes

Answers

The type of membrane that lines true cavities which are not connected to the outside of the body are known as serous membranes. Option (E) is the correct option.

What are serous membranes?

Serous membranes are delicate membranes that surround organs and line body cavities. They generate a thin layer of fluid that reduces friction as organs move within the cavities. These membranes cover the thoracic and abdominal cavity's surfaces and organs, reducing friction from muscle movement and cushioning against organ injury.

What are the other types of membranes?

Mucous membranes: Mucous membranes line body cavities exposed to the environment (e.g., digestive, respiratory, urinary tracts) and produce mucus. Mucus is a sticky substance that helps protect the body from microorganisms and lubricates the passage of food and waste products through the digestive system.Cutaneous membrane: The skin or cutaneous membrane is the body's largest and most visible membrane. It protects the body's internal organs and tissues from the environment and keeps water and nutrients in.Dialysis membranes: Dialysis membranes are thin films of semi-permeable material with uniform pores that are used to filter blood during hemodialysis.Synovial membranes: Synovial membranes line the synovial joint cavities, which are spaces between bones that allow for joint movement. The synovial fluid they produce lubricates the joint and reduces friction between the bones.

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Filtration of albumin... Als abnormal. B. Is normal with an increase in glomerular permeability C. Is damaging to nephrons. D. All of the above. E. None of the above 28 3 points Glomerular filtrate contains: A. Everything in the blood. O B. Everything in the blood except cells and proteins. C. Water and electrolytes. D. Water and waste. E. Water 293 points Alaboratory test that measures the level of nitrogen in the blood that is part of urea: A. BUN B. Plasma creatinine. C. Inulin clearance D. All of the above. Etwo of the above

Answers

Option A is correct.

Option B is correct.

The correct options are A and B.

Filtration of albumin is abnormal. The statement is true because albumin is a protein that is too large to pass through the glomerular filtration membrane. When it does, it indicates the membrane's increased permeability and its consequent inability to function correctly. Hence, option A is correct.

Glomerular filtrate contains everything in the blood except cells and proteins. It is because of the membrane's structure and its role in the filtration process. Hence, option B is correct.

Blood Urea Nitrogen (BUN) is a laboratory test that measures the level of nitrogen in the blood that is part of urea. The option A is correct. BUN testing is commonly used to determine how well the kidneys are working, as urea is removed from the body in urine, which is processed by the kidneys. In conclusion, the correct options are: A. Filtration of albumin is abnormal. B. Glomerular filtrate contains everything in the blood except cells and proteins.

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The most important catabolic pathways converge on what intermediate prior to entering the citric acid cycle?

Answers

The most important catabolic pathways converge on acetyl CoA prior to entering the citric acid cycle. Catabolic pathways break down large molecules into smaller ones, resulting in the release of energy.

The citric acid cycle, also known as the Krebs cycle or TCA cycle, is a series of reactions that generate ATP, or energy, from the breakdown of carbohydrates, fats, and proteins. The most important catabolic pathways, such as glycolysis, beta-oxidation, and amino acid catabolism, all converge on the acetyl CoA molecule. The pyruvate generated from glycolysis is converted into acetyl CoA, while fatty acids undergo beta-oxidation to form acetyl CoA. Amino acids undergo a series of reactions that convert them into acetyl CoA or other intermediates that can enter the citric acid cycle. Acetyl CoA then enters the citric acid cycle, where it undergoes a series of reactions that generate NADH and FADH2, which are then used to produce ATP in the electron transport chain.

The generation of acetyl CoA from the breakdown of carbohydrates, fats, and proteins is a crucial step in energy production and is a key component of cellular respiration. Without acetyl CoA, the citric acid cycle cannot proceed, and energy production comes to a halt. Therefore, acetyl CoA is an essential intermediate in catabolism.

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You and a friend were talking about the role of genes and the environment and your friend said, "DNA is destiny. The environment doesn't influence who someone becomes at all, it is all determined by genes." What can you tell your friend about the interaction of genes and environment? Include two examples discussed in class or the textbook to support your point.

Answers

Genes and the environment both contribute to a person's characteristics. A person's characteristics are not solely determined by genes but the environment also has an impact on who someone becomes. Two examples discussed in class or the textbook that support this point are intelligence and obesity.

The development of intelligence is influenced by both genes and the environment. Studies have shown that the genetic influence on intelligence increases with age. However, the environment is also crucial in developing intelligence. Studies have also shown that children who are raised in a stimulating environment, which includes exposure to language, reading, and other educational materials, have higher intelligence scores than children who are raised in a less stimulating environment.

Obesity is another example of how genes and the environment interact. Some people are more likely to become obese due to their genes. However, the environment also plays a significant role in determining whether someone becomes obese. For example, if someone with a genetic predisposition to obesity lives in an environment with limited access to healthy food and opportunities for physical activity, they are more likely to become obese than someone with the same genetic predisposition who lives in an environment that promotes healthy eating and physical activity.

In conclusion, the interaction of genes and the environment is an essential aspect of understanding human characteristics. DNA is not destiny, and the environment plays a significant role in shaping who someone becomes.

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"The phenomenon that closer objects are perceived to move faster compared to distant objects. O A. Retinal disparity O
B. Motion parallax
C. Optic flow

Answers

Motion parallax is the phenomenon where closer objects are perceived to move faster compared to distant objects. Option B. is correct.

Motion parallax refers to the phenomenon where closer objects appear to move faster than distant objects when an observer is in motion. It occurs due to the relative motion between the observer and the objects in the environment.

When an observer is moving, objects that are closer to them will appear to move across their visual field at a faster rate compared to objects that are farther away. This is because the closer objects have a larger apparent motion, as their displacement is more noticeable due to their proximity to the observer.

Motion parallax is a depth cue that our visual system uses to perceive and interpret the relative distances and depths of objects in the environment. It is particularly useful in perceiving depth when an observer is moving or when objects in the environment are in motion.

Therefore, option B. is correct.

The correct format of the question should be:

The phenomenon that closer objects are perceived to move faster compared to distant objects.

A. Retinal disparity

B. Motion parallax

C. Optic flow

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A 63-year-old woman attending a church service feels a tickle in her throat, which leads to an intense feeling of the need to cough. She suppresses the cough forcefully by holding it in for 10 seconds and as she stands up with the congregation, she feels light-headed. She immediately sits back down and feels fine. Which of the following best explains her light-headedness? A) Carbon dioxide retention leads to cerebrovascular dilatation B) Catecholamine release causes peripheral vasodilatation C) Hypoxemia slows the rate of firing of the sinoatrial node D) Increased intrathoracic pressure decreases venous return to the heart E) Irritation of the pericardium triggers premature ventricular contractions

Answers

Increased intrathoracic pressure decreases venous return to the heart. The correct option among the following is option D.

As per the given information, a 63-year-old woman attending a church service feels a tickle in her throat, which leads to an intense feeling of the need to cough. She suppresses the cough forcefully by holding it in for 10 seconds and as she stands up with the congregation, she feels light-headed. She immediately sits back down and feels fine.

The best explanation for her light-headedness is given in option 4, which states that increased intrathoracic pressure decreases venous return to the heart. Intrathoracic pressure is the pressure exerted within the thoracic cavity, which contains the lungs and heart.

An increased intrathoracic pressure makes it difficult for blood to return to the heart. As a result, less oxygenated blood is pumped to the brain and the person feels light-headed or may faint. Hence, D is the correct option.

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Compare these two structural diagrams.

Left: 2 C atoms are double bonded together, to H below left and above right, and to C H subscript 3 above left and below right. Right: Two C atoms are double bonded together, above left and right to C H subscript 3, and below left and right to H.

Which best describes the substances represented by these two diagrams?

They are the same compound because they have the same chemical formula and arrangement.

They are the same compound, but since they have different arrangements, they are not isomers of each other.

They are isomers of each other, but since they have different arrangements, they are not the same compound.

Answers

They are isomers of each other, but since they have different arrangements, they are not the same compound" accurately describes the relationship between the two diagrams the two structural diagrams represent different isomers of the same compound Isomers are molecules with the same chemical formula but different arrangements of atoms. D

In this case, both diagrams depict two carbon atoms that are double bonded to each other.

However, the arrangement of the attached atoms differs between the left and right diagrams.

In the left diagram, the two carbon atoms are double bonded, and one carbon atom is bonded to a hydrogen atom below on the left and above on the right. Additionally, this carbon atom is bonded to a methyl group (CH3) above on the left and below on the right.

On the other hand, the right diagram shows the two carbon atoms double bonded, with both carbon atoms bonded to methyl groups above and below, while also being bonded to a hydrogen atom below on the left and right

Although the two isomers have the same chemical formula, they are distinct compounds due to their different arrangements.

Isomers have different physical and chemical properties because their arrangement affects the interactions and bonding patterns of the atoms within the molecules.

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AMH Part 1: Identify the following components of the anti-Mullerian hormone signaling pathway by selecting the best answer to fill in each blank. The source of the anti-Mullerian hormone is the (Select] Its target is the Select 1 Its action on its target is to (Select]

Answers

The source of the anti-Mullerian hormone is the (Select: "Sertoli cells in the testes").

Its target is the (Select: "Mullerian ducts in the developing fetus").

Its action on its target is to (Select: "inhibit the development of female reproductive structures and promote the development of male reproductive structures").

The anti-Mullerian hormone (AMH) signaling pathway plays a crucial role in sexual development. The hormone is primarily produced by specialized cells called Sertoli cells in the testes of males. Its main target is the Mullerian ducts, which are present in the developing fetus and give rise to female reproductive structures such as the uterus, fallopian tubes, and upper vagina.

The action of AMH on its target is to inhibit the development of these female reproductive structures. By doing so, AMH promotes the development of male reproductive structures. This includes the regression of the Mullerian ducts, preventing the formation of the uterus and other female-specific organs.

AMH's role in sexual differentiation is essential for the development of male reproductive organs and the suppression of female reproductive structures. It helps establish the typical male reproductive system by directing the growth and differentiation of male-specific organs.

Understanding the components of the AMH signaling pathway is crucial in comprehending the mechanisms behind sexual development and the differentiation of male and female reproductive structures.

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An individual wants to reduce their risk of osteoporosis. What type of training recommendations would you give them based on the material from Chapter 5? What is the minimal essential strain? What type of exercises should they use? How should they progress?
Use the Essentials of Strength Training and Conditioning.
The book for the National Strength and Conditioning Association
Written by Baechle and Earle

Answers

To reduce the risk of osteoporosis, I would recommend a combination of weight-bearing and resistance exercises, focusing on high-impact activities and progressive overload.

Osteoporosis is a condition characterized by low bone mass and deterioration of bone tissue, leading to increased fragility and susceptibility to fractures.

Exercise plays a crucial role in maintaining and improving bone health. Based on the material from Chapter 5 of "Essentials of Strength Training and Conditioning" by Baechle and Earle, the following training recommendations can help reduce the risk of osteoporosis:

1. Weight-bearing exercises: Engaging in weight-bearing activities that require you to work against gravity is essential. Examples include walking, jogging, dancing, stair climbing, and hiking. These exercises put stress on your bones, stimulating them to become stronger.

2. Resistance exercises: Incorporating resistance training into your routine is crucial for increasing bone density. Exercises such as weightlifting, bodyweight exercises, and resistance band workouts help stimulate bone remodeling and enhance bone mineral density. Focus on exercises that target major muscle groups, including the legs, hips, spine, and arms.

3. High-impact activities: Including high-impact exercises in your training regimen can provide additional benefits for bone health. These activities involve brief periods of jumping, such as plyometrics or jumping rope. They generate greater forces on the bones, promoting bone strength.

4. Progressive overload: To see ongoing improvements, it's important to gradually increase the intensity and challenge of your exercises. This principle of progressive overload ensures that your bones are consistently stimulated and adapt to the stress placed upon them. Start with manageable loads and progress gradually over time.

In summary , By combining weight-bearing exercises, resistance training, high-impact activities, and applying the principle of progressive overload, individuals can effectively reduce their risk of osteoporosis. It's important to consult with a healthcare professional or a qualified strength and conditioning specialist to tailor an exercise program that suits individual needs and abilities.

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chromosomes are lined up by spindle fibers. nuclear envelope forms around each set of dna. sister chromatids are pulled apart. centromeres move toward the poles of the cell.

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Chromosomes line up by spindle fibers, the nuclear envelope forms around each set of DNA, sister chromatids are pulled apart, and centromeres move toward the poles of the cell during anaphase of mitosis.

Anaphase is the fourth phase of mitosis, which begins after the metaphase stage of cell division. During anaphase, chromosomes are pulled apart from the center of the cell to opposite poles by spindle fibers, resulting in sister chromatids. This stage is critical in separating chromosomes equally into daughter cells during cell division.

In this phase, the nuclear envelope reforms around the two groups of chromosomes that form at opposite poles of the cell. The mitotic spindle fibers, attached to the kinetochores of the chromosomes, are shortened, pulling apart the sister chromatids at the centromeres.

As the spindle fibers shorten and move the chromosomes towards the poles, the centromeres move towards the poles of the cell, which effectively pulls the sister chromatids to opposite sides of the cell. This stage marks the beginning of cytokinesis, which is when the cell membrane starts to form in the center of the cell to separate the two new daughter cells.

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The olfactory epithelium does NOT include:
Olfactory receptor cell
Olfactory vesicle
Glomerulus
Supporting cell
Basal cell

Answers

The olfactory epithelium does NOT include glomerulus.

What is the olfactory epithelium?

The olfactory epithelium is a specialized tissue located in the upper nasal cavity. It's composed of different cell types that work together to sense and transmit odors to the brain. The olfactory receptor cells, which are sensory neurons that contain specialized proteins called receptors that detect odor molecules, are among the cell types. The olfactory receptor cells are responsible for detecting odors and transmitting signals to the brain through the olfactory nerve.

The olfactory epithelium also contains supporting cells, which provide structural and metabolic support to the olfactory receptor cells; basal cells, which are immature cells that differentiate into olfactory receptor cells and replace old or damaged ones; and Bowman's glands, which are mucus-secreting glands that aid in odor detection by dissolving odor molecules.

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Give a description of the characteristics/features of a midlife crisis, including the different experiences in terms of gender. Be sure to explain how biology intersects with psychology and social factors in this phenomenon by providing an example. How can a social worker help a person navigate a midlife crisis?

Answers

A midlife crisis is a period of self-evaluation and reflection that occurs when a person reaches middle age.  The midlife crisis is characterized by different features and characteristics for men and women, and biological, psychological, and social factors all contribute to this phenomenon.

The midlife crisis is often marked by feelings of dissatisfaction with their career or personal life. Men may experience a loss of energy, motivation, and passion for life. They may also feel like they have not accomplished enough in their lives and may become preoccupied with their mortality. Women, on the other hand, may experience a midlife crisis that is more focused on their personal relationships. They may feel a sense of dissatisfaction with their marriage or family life, and may begin to question their roles as wives and mothers. Women may also become preoccupied with their physical appearance and may feel pressure to maintain a youthful appearance. Biology plays a role in the midlife crisis in that hormonal changes can impact mood and behavior. For example, men experience a decline in testosterone production, which can lead to feelings of depression and fatigue.

Social workers can also connect clients with resources and support systems to help them achieve their goals and find meaning and purpose in their lives. By addressing biological, psychological, and social factors, social workers can help clients navigate the midlife crisis and emerge stronger and more resilient.

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What anatomical feature of the fallopian tubes
allows sexually transmitted infections to
sometimes spread into the abdomen in women?

Answers

The anatomical feature of the fallopian tubes that allows sexually transmitted infections to sometimes spread into the abdomen in women is their open ends.

The fallopian tubes are a pair of narrow tubes that connect the ovaries to the uterus. Their main function is to transport eggs from the ovaries to the uterus. The open ends of the fallopian tubes, called fimbriae, are located near the ovaries and have finger-like projections that help capture released eggs.

However, the open ends of the fallopian tubes also create a potential pathway for infection. If a woman contracts a sexually transmitted infection (STI) such as chlamydia or gonorrhea, the bacteria or other pathogens can enter the fallopian tubes through the cervix during sexual activity. From there, the infection can ascend through the tubes and reach the abdominal cavity.

The presence of an STI in the fallopian tubes can lead to a condition called pelvic inflammatory disease (PID), which is characterized by inflammation and infection of the reproductive organs. If left untreated, PID can cause serious complications, including infertility, chronic pelvic pain, and in severe cases, abscesses or scarring in the fallopian tubes.

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Q- Protein complementation is most important for which of the
following people?
a. pescatarians (vegetarians who eat fish)
b. vegans
c. lacto-ovo vegetarians
d. meat eaters

Answers

Protein complementation is most important for vegans to ensure they consume a complete protein diet. Option b .

Protein complementation is a method of combining different plant-based proteins to get all the essential amino acids. Vegans and vegetarians usually rely on plant proteins, so combining a variety of protein sources to achieve a complete amino acid profile is vital.

Vegans usually rely on plant-based protein sources, which may lack one or two essential amino acids. Animal-based protein is a complete protein that contains all nine essential amino acids. Therefore, vegans must combine two or more plant-based proteins that complement each other to achieve a complete amino acid profile.

Combining a variety of plant-based proteins like nuts, grains, seeds, and legumes can help achieve the recommended daily intake of essential amino acids that are typically abundant in animal-based proteins. The correct option is b. vegans.

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9. How would pulmonary hyperventilation affect each of the following?
A.) PO2 of alveolar air
B.) PO2 of alveolar air C.) PCO2 of alveolar air D.) PCO2 of arterial blood

Answers

PCO2 of arterial blood: There would be a decrease in the partial pressure of carbon dioxide (PCO2) of arterial blood. Because CO2 is removed faster from the body, the arterial partial pressure of carbon dioxide (PaCO2) decreases as well.

Pulmonary hyperventilation can affect each of the following ways:

1. PO2 of alveolar air:There would be an increase in the partial pressure of oxygen (PO2) of alveolar air. When pulmonary hyperventilation occurs, oxygen enters the lungs at a quicker pace, resulting in an increase in the partial pressure of oxygen (PO2) of alveolar air.

2. PO2 of arterial blood: There would be an increase in the partial pressure of oxygen (PO2) of arterial blood. Pulmonary hyperventilation causes the alveolar partial pressure of oxygen (PAO2) to increase, which raises the amount of oxygen in the arterial blood, resulting in an increase in the partial pressure of oxygen (PO2) of arterial blood.

3. PCO2 of alveolar air:There would be a decrease in the partial pressure of carbon dioxide (PCO2) of alveolar air. Pulmonary hyperventilation can cause carbon dioxide to exit the lungs faster, resulting in a decrease in the partial pressure of carbon dioxide (PCO2) of alveolar air.

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The statement that is not true regarding the usefulness of a careful clinical evaluation of the site of bleeding is that Answers A-D a. von Willebrand disease can present with gum and mucus membrane bleeding b. In people whose diet lacks fresh fruits, bleeding gums is a common manifestation c. In severe Hemopa bleeding is typically into the skin and mucus membrane d. Prolonged bleeding from superficial cuts is indicative of platelet disorders

Answers

The statement that is not true regarding the usefulness of a careful clinical evaluation of the site of bleeding is B. In people whose diet lacks fresh fruits, bleeding gums is a common manifestation.

Bleeding, also known as hemorrhaging, is blood flowing from a ruptured or damaged blood vessel. Bleeding can be internal, which means that it occurs inside the body, or external, which means that it occurs outside the body, such as from a cut or wound. Bleeding symptoms differ depending on the cause and the affected area, but they are all the result of the same process.The usefulness of a careful clinical evaluation of the site of bleeding:It is essential to conduct a careful clinical evaluation of the site of bleeding.

Bleeding symptoms might provide information on the underlying cause, including the site of bleeding, the extent and duration of bleeding, and the pattern of bleeding, among other things. However, the assertion that people whose diet lacks fresh fruits have bleeding gums is false.Bleeding gums are commonly associated with periodontal (gum) disease, which is caused by poor dental hygiene, tooth decay, and gum infection. Lack of fruits, on the other hand, might cause scurvy, which might cause gum bleeding. Scurvy is a rare disease that is caused by a deficiency of vitamin C and has been virtually eliminated in the Western world due to modern diet supplementation.

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What kind of membrane transport does Na+/K+ pump the use and why
is this necessary? Complete answers should consider the
thermodynamics of the system

Answers

The Na+/K+ pump utilizes primary active transport to transfer molecules across the cell membrane. This procedure necessitates the consumption of energy in the form of ATP to pump out three Na+ ions out of the cell and two K+ ions into the cell.

The pump accomplishes this goal by using the energy from ATP hydrolysis, which generates ADP and a phosphate group. The Na+/K+ pump is essential for maintaining the concentration gradient of Na+ and K+ ions across the cell membrane. This gradient is significant in the generation of an electrical potential in the cell membrane, which is necessary for a variety of cellular processes.

The generation of an electrical potential is determined by the concentration of Na+ and K+ ions across the membrane. The pump creates a large concentration gradient of these ions by pumping out Na+ and bringing in K+ into the cell. This creates an electrical potential that aids in the transportation of molecules and the transmission of signals across the cell membrane.

The Na+/K+ pump is also necessary for osmoregulation, which involves the maintenance of the cell's internal water balance. Na+ and K+ are electrolytes that assist in maintaining the osmotic equilibrium of the cell. The Na+/K+ pump plays an essential role in the regulation of ion concentrations and pH, as well as the removal of toxic materials from the cell.

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types of crowns in terms of the material they are made of
( PFM, All Ceramic Restoration, Full Metal Restoration )
Compare the types in terms of:
1- Advantages
2- Disadvantages
3- Indications
4- Contraindications

Answers

Crowns can be categorized based on the material they are made of. There are various types of crowns, including porcelain-fused-to-metal (PFM), all-ceramic restoration, and full-metal restoration.

They are compared based on their advantages, disadvantages, indications, and contraindications.

PFM Advantages:

PFM crowns are strong and long-lasting. They are less prone to chipping and breakage when compared to all-ceramic crowns.

Aesthetics:

PFM crowns have better aesthetics than full-metal crowns. They have a metal substructure covered with porcelain, which provides a more natural look.

Disadvantages:

Metal substrate: The metal substrate of PFM crowns can be seen through the porcelain, particularly in cases where there is a thinning of the gums or teeth. Indications: PFM crowns are ideal for patients who want strong and long-lasting crowns and those who need to have a crown for a back tooth.

Contraindications:

Patients with metal allergies or sensitivities should not get PFM crowns.

All-Ceramic Restoration Advantages:

All-ceramic crowns provide the most natural-looking teeth. They are highly translucent, providing a natural appearance.

Biocompatibility:

Ceramic materials are non-toxic and biocompatible. They are also highly resistant to corrosion and decay.

Disadvantages:

Fragility: All-ceramic crowns are more fragile than PFM crowns. They are also more prone to chipping or breaking, particularly if they are not appropriately maintained. Cost: All-ceramic crowns are more expensive than PFM or full-metal crowns.Indications: All-ceramic crowns are ideal for patients who want a natural-looking crown, especially for their front teeth.Contraindications: Patients with bruxism should not get all-ceramic crowns.

Full-Metal Restoration Advantages:

 Full-metal crowns are the strongest and longest-lasting crowns. They are highly resistant to chipping and breaking. Indications: Full-metal crowns are ideal for patients who need crowns for back teeth, especially if they grind their teeth.

Contraindications:

Full-metal crowns are not recommended for patients who want a crown for their front teeth due to their metallic appearance. They can also cause galvanic shock or be aesthetically unappealing.According to the above discussion, different types of crowns have their advantages and disadvantages. Therefore, the dentist should choose the crown type based on the patients' individual needs and preferences.

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Which of the following is a TRUE statement? (Check all that apply) a. During hemostasis, the platelets aggregation is characterized by a positive feedback loop. b. During hemostasis, aggregating platelets release serotonin and other products in a process called platelet lytic reaction. c. During hemostasis, ADP and thromboxane d. A both promote platelet aggregation and vasoconstriction With regards to hemostasis, prostacyclin and NO are antagonists to serotonin and thromboxane. e. CD39 specifically inhibits platelet aggregation. f. A fluid called plasma is formed during the process of clot retraction. g. Platelets contribute to secondary hemostasis by providing phospholipids and binding sites for fibrinogen and fibrin. h. Blood clotting in a test tube essentially involves the extrinsic pathwghmof secondary hemostasis i. The intrinsic pathway of secondary hemostasis is initiated by thromboplastin. j. Hydrophilic surfaces and negatively charged structures initiate the contact pathway of secondary hemostasis.

Answers

The correct statements are:

a. During hemostasis, the platelet aggregation is characterized by a positive feedback loop.

c. During hemostasis, ADP and thromboxane A2 both promote platelet aggregation and vasoconstriction.

g. Platelets contribute to secondary hemostasis by providing phospholipids and binding sites for fibrinogen and fibrin.

i. The intrinsic pathway of secondary hemostasis is initiated by thromboplastin.

During hemostasis, platelet aggregation is a crucial step in forming a stable blood clot. Platelets release various substances, including ADP and thromboxane A2, which promote platelet aggregation and vasoconstriction, enhancing the clotting process. This positive feedback loop amplifies platelet aggregation. Platelets also contribute to secondary hemostasis by providing phospholipids and binding sites for fibrinogen and fibrin, essential components for clot formation. The intrinsic pathway of secondary hemostasis is initiated by thromboplastin, not the extrinsic pathway. Therefore, options a, c, g, and i are the correct statements.

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An injection into the spinal column is referred to as:_______

a. intrasynovial

b. intradermal

c. intravenous

d. intrathecal

Answers

An injection into the spinal column is referred to as: intrathecal.

Therefore correct answer is option d.

An injection into the spinal column is known as an intrathecal injection. It involves the administration of medication or other substances directly into the subarachnoid space of the spinal cord. This route of administration allows for targeted delivery of drugs to the central nervous system.

The subarachnoid space is the area between the arachnoid mater and the pia mater, which are protective membranes surrounding the spinal cord. By injecting a substance into this space, it can diffuse into the cerebrospinal fluid (CSF) that surrounds the spinal cord and brain, reaching the target sites within the central nervous system.

Intrathecal injections are commonly used in medical practice for various purposes. One of the most common applications is the administration of spinal anesthesia, where local anesthetic agents are injected into the subarachnoid space to induce numbness and prevent pain during surgical procedures.

In addition to anesthesia, intrathecal injections can also be utilized for the delivery of certain medications, such as opioids or chemotherapy drugs, directly to the spinal cord or brain. This targeted approach can enhance the therapeutic efficacy and minimize systemic side effects associated with systemic drug administration.

The administration of an intrathecal injection requires specialized knowledge and skills and is typically performed by trained healthcare professionals, such as anesthesiologists or neurologists. Strict aseptic techniques and precautions are followed to minimize the risk of infection or other complications.

Overall, intrathecal injections provide a valuable route of administration for delivering drugs or substances to the central nervous system, allowing for localized effects and targeted therapeutic interventions.

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QUESTION The uterine tubes have the same function as the ductus deferens in males: to transport sex cells ◯ True O False QUESTION 32 Increased tubular secretion of H* means that more acid is being excreted in the urine. O True O False QUESTION 33 During a monthly cycle, several follicles begin to develop but usually only one becomes dominant and survives to be ovulated. O True O False QUESTION 34 Which is TRUE if a person has plasma HCO3 levels that are above normal? O A high (HCO3] is compensating for an acid-base problem O B. high (HCO3") is causing an acid-base problem O C. high (HCO3"] means the blood pH is too acidic O D. high (HCO3) means the blood pH is too basic O E. it cannot be determined if high (HCO3) is a cause or a compensation without also knowing the blood pH and

Answers

1. The given statement, "The uterine tubes have the same function as the ductus deferens in males: to transport sex cells" is false because the uterine tubes carry an ovum from the ovary to the uterus, where fertilization by sperm can take place. In males, the ductus deferens carries sperm from the epididymis in anticipation of ejaculation.

2. The given statement, "Increased tubular secretion of H* means that more acid is being excreted in the urine" is false because Increased tubular secretion of H+ means that acid is being excreted from the body, but it is removed through urine as hydrogen ions are not found in urine.

3. The given statement, "During a monthly cycle, several follicles begin to develop but usually only one becomes dominant and survives to be ovulated is true because multiple follicles start to develop in the ovaries at the start of each menstrual cycle, but only one of them usually grows and matures completely, releasing an egg during the ovulation process.

4. The given statement, "A high (HCO₃) is compensating for an acid-base problem" is true because an elevated level of bicarbonate (HCO₃) in the plasma indicates compensation for an acid-base imbalance, typically a metabolic acidosis. It helps to buffer and restore the pH balance.

1. The uterine tubes, also known as fallopian tubes, have a different function from the ductus deferens in males. In females, the uterine tubes transport eggs (or sex cells) from the ovaries to the uterus. On the other hand, the ductus deferens in males carry sperm cells from the testes to the urethra for ejaculation. The uterine tubes and the ductus deferens serve different roles in the reproductive systems of males and females.

2. Increased tubular secretion of H+ does not necessarily mean that more acid is being excreted in the urine. Tubular secretion of hydrogen ions (H+) primarily occurs in the kidneys as part of the acid-base regulation process. It helps in maintaining the body's pH balance by excreting excess H+ ions and reabsorbing bicarbonate ions (HCO³⁻) to regulate acidity. However, the actual amount of acid excreted in the urine depends on various factors, including dietary intake, metabolic processes, and overall acid-base balance.

3. During the menstrual cycle, multiple follicles start to develop in the ovaries. Each follicle contains an immature egg. However, typically only one dominant follicle continues to grow and mature, while the others undergo a process called atresia and do not reach maturity. The dominant follicle eventually releases a mature egg through ovulation.

4. If the plasma bicarbonate (HCO³) levels are above normal, it suggests that the body is compensating for an acid-base problem, usually metabolic acidosis. Bicarbonate acts as a buffer to help maintain the acid-base balance in the body. An elevated level of bicarbonate indicates an attempt to restore the pH balance by increasing its concentration, helping to counteract the excess acidity and maintain the normal acid-base levels.

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