Fed-batch fermentation is a batch culture of microorganisms with an additional feeding of a nutrient solution to the culture medium to maintain a constant nutrient concentration.
Fed-batch fermentation can increase the yield of a recombinant protein of your choice in the following ways:i. By maintaining a nutrient level in the growth medium.ii. By extending the logarithmic growth phase of the microorganism.iii. By increasing cell density. All these factors lead to increased productivity. There are various technologies used to purify recombinant proteins. The technologies include but are not limited to: i. Affinity chromatography ii. Ion-exchange chromatography iii.
Hydrophobic interaction chromatography iv. Gel filtration chromatography These technologies are based on the different physical and chemical properties of proteins like molecular weight, charge, hydrophobicity, and specific binding properties. Affinity chromatography Affinity chromatography is a chromatographic method that exploits the unique binding characteristics of proteins. It uses a solid phase consisting of a matrix covalently linked to a specific ligand. When a protein sample is passed over the matrix, the protein will bind to the ligand, while other molecules are washed away.
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Part 2: Muscle Structure 1. Your textbook and the internet have excellent examples of microscopic structure of cardiac, skeletal, and smooth muscle. Draw and label cardiac, skeletal, and smooth muscle tissue as it looks microscopically, based on what you look up in your textbook or on the internet. Identify the nuclei (all muscle types), striations (skeletal muscle) and intercalated discs (cardiac muscle). cardiac: skeletal: Smooth: 2. What is the name for the type of tissue that joins muscle to bone? What type of tissue are these structures made of? What is their function? 3. What is the name of the tissue that connects bones to other bones? What type of tissue are these structures made of? What is their function?
Here are the microscopic structure of cardiac, skeletal and smooth muscle tissue as it looks like: Cardiac muscle: Striated, involuntary muscle tissue found only in the heart.
Cardiac muscles are responsible for contraction and relaxation of the heart, which enables the blood to circulate throughout the body. Here is the labeled microscopic structure of cardiac muscle: Skeletal muscle: Striated, voluntary muscle that controls the movement of bones. The muscle is comprised of muscle fibers that are fused together and contains multiple nuclei. Here is the labeled microscopic structure of skeletal muscle: Smooth muscle: Non-striated, involuntary muscle that controls the movement of internal organs such as blood vessels, stomach and intestines.
Here is the labeled microscopic structure of smooth muscle: Connective tissue is the name of the tissue that joins muscle to bone. These structures are made up of fibrous connective tissue. Their function is to transmit the forces produced by the contraction of muscles to the bones that they are attached to. Ligament is the name of the tissue that connects bones to other bones. Ligaments are made up of dense, fibrous connective tissue. Their function is to provide stability to joints by connecting bones together and limiting their movement.
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When moving from terminal stance to pre-swing, the hip joint osteokinematic sagittal plane action is: a. Extension
b. Adduction
c. Abduction
d. Flexion
Thus, Option D is correct - Flexion. When moving from terminal stance to pre-swing, the hip joint osteokinematic sagittal plane action IS Flexion.
When moving from terminal stance to pre-swing, the hip joint osteokinematic sagittal plane action is flexion.
Osteokinematics is the movement of bone in relation to the three cardinal planes of the body. The three cardinal planes are the sagittal, frontal and transverse planes. Sagittal plane motions are those that occur as flexion and extension movements.
Frontal plane motions involve abduction and adduction movements, while transverse plane motions involve internal and external rotation.
When moving from the terminal stance to pre-swing, the hip joint osteokinematic sagittal plane action is flexion.
The sagittal plane passes from anterior to posterior and divides the body into left and right halves. The joint movements that occur in this plane are flexion, extension, dorsiflexion, and plantar flexion.Thus, Option D is correct - Flexion.
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medial temporal lobes. caudal Head pons lateral eye movement sciatic nerve taste sensation Midbrain 31 pairs inner ears PNS 12 pairs medullar oblongata fibular nerve superior oblique hip joints Medially simultaneously Ischial gluteal upper limbs CNS dorsal root and ventral roots extrinsic eye sensory and motor signals anterior thigh occipital lobes neck taste sensations skeletal muscles crossed extensor rami intrinsic and extrinsic thoracic and abdominopelvic quadricep visceral signals Hearing anterolateral somatosensory cortex encapsulated nerve sense organ motor neuron larynx and pharynx effectors biceps and skin lumbosacral maxillary nerve spinal cord thermoreceptors and nociceptor lateral rectus medial arm the pons and the medullar oblongata nerve plexus mastication in the mouth. sternocleidomastoid abdominal wall and iliopsoas stretch reflex odorant stimuli side opposite 3 types internal and internal Heart optic chiasma nociceptors Foot swallowing somatic motor signals Golgi tendon interceptors interneuron photoreceptors deltoid teres minor exteroceptors thermoreceptors Electromagnetic Afferent triceps brachii anterior forearm develop command abductor anterior special sense vision, and taste two criterial neurological and sensory chemoreceptors multiple synapses Mechanoreceptors tibia monosynaptic stretch thermoreceptors synapses Afferent Eye withdrawer organs
1. The peripheral nervous system connects the body and environment to the…………………………. The PNS detects sensory stimuli and transmit it to the ……………………... The ……………………………. in turn process the sensory information, develop command, and send it via the ……………………….to the PNS effector like muscles and glands.
2. Cranial nerves are attached to structures in the………………. and …………………… regions of the body. These are sensory nerves, the motor nerves and the mixed motor and sensory nerves. There are ………………of cranial nerves named with Roman figures for nerve one to nerve twelve.
3. The trochlear nerve that moves the eye ………………………and inferiorly, originates from the inferior portion of the…………………………, and terminate on the …………………………. muscles of the eye. The oculomotor motor nerve that also move the eye originates from the superior and lateral portions of the ……………………. and terminate on the …………………………………. muscles and smooth muscles of the eye. The vestibulocochlear verve that controls ………………………….and equilibrium, originates from the vestibular and cochlear nerves of the………………., and terminates on nuclei of the cerebellum and……………………………….
4. The optic nerve that carries visual information, originates from the posterior of the………………………., and form an X-shaped structure called……………………., and terminates on the nuclei of the ……………………….and midbrain before it gets to the visual cortex of the…………………………... The olfactory nerve that carries……………………, originates form the olfactory epithelia and terminates on nuclei of the …………………………….
5. The vagus nerve is a mixed nerve that is responsible for the contraction of muscles surrounding the………………………………, originates from the …………………….and sensory receptors from the pharynx, larynx, skin, ears, certain blood vessels of the neck, innervate throat, anterior neck, visceral organs of …………………………… cavities. The glossopharyngeal nerves are mixed nerves responsible for ………………………. movement, originates from the……………………., and sensory receptor of the tongue, pharynx, and round the ears.
The correct options that fill in the gaps about the peripheral nervous system are:
1. central nervous system, central nervous system, central nervous system, motor neurons.
2. head and neck, twelve pairs
3. superiorly, midbrain, superior oblique, midbrain, extraocular; hearing; inner ear, auditory cortex.
4. eyeball, optic chiasm, thalamus, occipital lobe; olfactory sensations, olfactory bulb.
5. viscera, medulla oblongata, thoracic and abdominal cavities; swallowing; medulla oblongata.
What is the role of the peripheral nervous system?1. The peripheral nervous system connects the body and environment to the central nervous system. The PNS detects sensory stimuli and transmits it to the central nervous system. The central nervous system in turn processes the sensory information, develops commands, and sends them via the motor neurons to the PNS effectors like muscles and glands.
2. Cranial nerves are attached to structures in the head and neck regions of the body. These are sensory nerves, motor nerves, and mixed motor and sensory nerves. There are twelve pairs of cranial nerves named with Roman numerals for nerve one to nerve twelve.
3. The trochlear nerve that moves the eye superiorly and inferiorly, originates from the inferior portion of the midbrain and terminates on the superior oblique muscles of the eye. The oculomotor motor nerve that also moves the eye originates from the superior and lateral portions of the midbrain and terminates on the extraocular muscles and smooth muscles of the eye. The vestibulocochlear nerve that controls hearing and equilibrium, originates from the vestibular and cochlear nerves of the inner ear and terminates on nuclei of the cerebellum and auditory cortex.
4. The optic nerve that carries visual information originates from the posterior of the eyeball, and forms an X-shaped structure called optic chiasm, and terminates on the nuclei of the thalamus and midbrain before it gets to the visual cortex of the occipital lobe. The olfactory nerve that carries olfactory sensations, originates from the olfactory epithelia and terminates on nuclei of the olfactory bulb.
5. The vagus nerve is a mixed nerve that is responsible for the contraction of muscles surrounding the viscera, originates from the medulla oblongata, and sensory receptors from the pharynx, larynx, skin, ears, certain blood vessels of the neck, innervate the throat, anterior neck, visceral organs of the thoracic and abdominal cavities. The glossopharyngeal nerves are mixed nerves responsible for swallowing movement, originates from the medulla oblongata, and sensory receptors of the tongue, pharynx, and around the ears.
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In skeletal muscle, when there is maximal load, the velocity of contraction equals 0. This is considered what type of contraction?
Group of answer choices
a. Shortening
b. Lengthening
c. Isometric
d. Isotonic
The correct option is "c. Isometric." An isometric contraction occurs when a muscle generates force without changing its length.
The term "isometric" is derived from the words "iso" meaning same and "metric" meaning length, indicating that the muscle remains the same length during contraction.
During an isometric contraction, the muscle exerts maximum force but does not undergo any shortening or lengthening. This can be observed when there is a maximal load, and the velocity of contraction becomes zero.
In this scenario, the muscle is generating its highest force output while maintaining a fixed length.
Therefore, an isometric contraction refers to a muscle contraction where force is produced without any change in muscle length.
It is characterized by the absence of movement and a constant muscle length during contraction. In the context of the statement, when the velocity of contraction equals zero with maximal load, it signifies an isometric contraction.
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Why does a monozygotic (identical) twin only have a 50% chance
of developing schizophrenia if their identical twin develops
schizophrenia?
The 50% chance of developing schizophrenia in a monozygotic (identical) twin when their twin develops schizophrenia can be attributed to a combination of genetic and environmental factors.
While monozygotic twins share the same genetic material, they are not completely identical in terms of gene expression and environmental influences. Schizophrenia is a complex disorder believed to result from a combination of genetic predisposition and environmental triggers.
Although monozygotic twins have a higher genetic similarity compared to dizygotic twins or non-twin siblings, it does not guarantee that both twins will develop schizophrenia.
Several factors contribute to the variability in the development of schizophrenia in monozygotic twins. These include epigenetic modifications, which can influence gene expression and lead to differences in phenotypic outcomes.
Additionally, environmental factors such as prenatal conditions, early life experiences, and social interactions can play a significant role in triggering or modulating the expression of schizophrenia-related genes.
Therefore, despite sharing the same genetic background, the occurrence of schizophrenia in one twin does not guarantee its manifestation in the other twin due to the complex interplay between genetic and environmental factors.
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Why did the researchers split each female frog's eggs into two batches for fertilization by different males? Why didn't they mate each female with a single male frog?
The researchers split each female frog's eggs into two batches for fertilization by different males to study the effects of genetic diversity on the offspring. By mating each female with multiple males, they could observe variations in traits and understand the role of genetic diversity in adaptation and evolutionary processes.
The researchers split the eggs of each female frog into two batches and fertilized them with different males to examine the effects of genetic diversity on the offspring. This method helps them observe trait variations and understand the importance of genetic diversity in adaptation and evolution. It allows for the study of diverse paternal genes' impact on offspring characteristics and fitness. This research aids in understanding how genetic variation contributes to phenotypic diversity and the overall health of populations. Additionally, it has implications for conservation biology by assessing the significance of genetic diversity in managing and preserving endangered species.
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Name the 2 hormones produced in the islets of Langerhans that regulate blood glucose levels, and the cells that produce them. Explain
Insulin and glucagon, produced by beta and alpha cells in the islets of Langerhans, respectively, work together to regulate blood glucose levels, ensuring their balance and normal functioning.
The two hormones produced in the islets of Langerhans that regulate blood glucose levels, and cells that produce them are: Insulin and Glucagon are the two hormones that are produced in the islets of Langerhans that regulate blood glucose levels.
Insulin is secreted by beta cells in the pancreas, and its function is to reduce blood glucose levels by increasing the uptake of glucose by cells, particularly liver, muscle, and adipose cells. Glucagon, on the other hand, is secreted by alpha cells in the pancreas.
It raises blood glucose levels by stimulating the liver to break down glycogen into glucose, which is then released into the bloodstream. Both of these hormones are critical in maintaining normal blood glucose levels.
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A 50-year-old man comes to the clinic because of excruciating pain in his right great toe. He describes the pain as so severe that it woke him from a deep sleep. He denies any similar episodes in the past. He admits to a few "drinking binges" over the past 2 weeks. His temperature is 100.5 degree Fahrenheit, blood pressure is 130/90 mm Hg, and pulse is 80/min. PE shows inflamed big toe. Joint aspiration show chalky-white deposits. Which of the following is the most likely diagnosis?
a) Osteoarthritis
b) Rheumatoid arthritis
c) Lyme arthritis
d) Gout
The most likely diagnosis of a 50-year-old man who has excruciating pain in his right great toe, with a fever, and blood pressure of 130/90 mm Hg, and inflamed big toe is Gout.option d is correct.
Gout is a type of arthritis that occurs when uric acid crystals accumulate in the joints, causing sudden pain, swelling, and inflammation. Uric acid is a chemical that is produced when the body breaks down substances known as purines.
The crystals can form in the joints, causing gout attacks.Gout is characterized by sudden, severe pain in one or more joints, usually the big toe. It can also affect the ankle, knee, wrist, elbow, and other joints. People with gout typically experience sudden, severe attacks of pain, swelling, and inflammation in the affected joint(s). Treatment of gout involves medications to reduce pain and inflammation, as well as medications to prevent future attacks
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rebecca m. woods, jarred m. lorusso, harry g. potter, joanna c. neill, jocelyn d. glazier, reinmar hager, maternal immune activation in rodent models: a systematic review of neurodevelopmental changes in gene expression and epigenetic modulation in the offspring brain, neuroscience
The research article, "Maternal immune activation in rodent models a systematic review of neurodevelopmental changes in gene expression and epigenetic modulation in the offspring brain," is a review of research on the impact of maternal immune activation on neurodevelopmental changes in the brains of rodent offspring.
The review covers research on changes in gene expression and epigenetic modulation that occur in the offspring's brain due to maternal immune activation. The review found that maternal immune activation can cause significant neurodevelopmental changes in rodent offspring.
- The article under study is a systematic review of research on the impact of maternal immune activation on neurodevelopmental changes in the brains of rodent offspring.
- The researchers review studies that looked at changes in gene expression and epigenetic modulation in the brains of rodent offspring due to maternal immune activation.
- The review found that maternal immune activation can lead to significant neurodevelopmental changes in rodent offspring, including changes in the expression of genes involved in brain development and function, as well as changes in epigenetic markers associated with neuronal differentiation and synaptic plasticity.
The research article under study is a systematic review of research on the impact of maternal immune activation on neurodevelopmental changes in the brains of rodent offspring.
The review covers studies that investigated the changes in gene expression and epigenetic modulation in the brains of rodent offspring due to maternal immune activation. The study found that maternal immune activation could cause significant neurodevelopmental changes in rodent offspring.
The review found that changes in gene expression and epigenetic modulation in the brains of rodent offspring due to maternal immune activation could be long-lasting and have significant effects on brain development and function.
Maternal immune activation can lead to changes in the expression of genes involved in brain development and function, as well as changes in epigenetic markers associated with neuronal differentiation and synaptic plasticity.
Overall, this systematic review provides a comprehensive analysis of research on maternal immune activation and its effects on neurodevelopment in rodent offspring.
The findings highlight the importance of understanding the mechanisms underlying the effects of maternal immune activation on offspring brain development and may have implications for the prevention and treatment of neurodevelopmental disorders.
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Explain the concept of nature vs. nurture". Which is more important for shaping our behavor?
The concept of "nature vs. nurture" is a debate that explores whether an individual's personality, intelligence, and behavior are the result of genetics or environment. It refers to the genetic factors that influence a person's character, and nurture refers to the environmental and social factors that influence a person's character.
The concept of "nature vs. nurture" examines whether an individual's personality, intelligence, and behavior are a product of genetics or the environment. The role of genetics and the environment in shaping behavior and personality has been a matter of controversy among psychologists for decades.
Nature refers to a person's hereditary or innate characteristics, which include their genetic makeup. Nurture, on the other hand, includes all of the environmental and social factors that influence a person's character. Some examples of environmental factors that can influence a person's behavior include social conditioning, upbringing, life experiences, cultural factors, and physical surroundings .The interaction between genetics and environment is essential to shape behavior, and both factors are interrelated.
Nature and nurture influence a person's character and shape his or her personality. While genetics may provide a foundation for personality and behavior, the environment plays a vital role in shaping personality traits. Studies have shown that the environment can have a profound impact on shaping an individual's character and personality. There is no clear answer to the question of whether nature or nurture is more important for shaping behavior.
Both factors play a vital role in shaping personality and behavior, and both factors are equally important. The environment plays a vital role in shaping personality traits, while genetics may provide a foundation for personality and behavior.
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The amount of blood that is ejected by one ventricle during systole is called the _____
a. End systolic volume b. End dustolic volume c. Stroke volume d. Ejection fraction
c. The amount of blood that is ejected by one ventricle during systole is called the Stroke volume.
The amount of blood that is ejected by one ventricle during systole is called the stroke volume. It represents the volume of blood pumped out of the ventricle with each heartbeat. Stroke volume is an important measure of cardiac function and is determined by factors such as the preload (amount of blood returning to the heart), afterload (resistance the heart has to overcome to pump blood), and contractility (force of ventricular contraction). It is typically measured in milliliters per beat. Stroke volume is an essential component in calculating other cardiac parameters, such as cardiac output (the volume of blood pumped by the heart per minute) which is calculated by multiplying stroke volume by heart rate.
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An otherwise healthy, 72 year-old man has had increasing difficulty with urination for the past 10 years. He now has to get up several times each night because of a feeling of urgency, but each time the urine volume is not great. He has difficulty starting and stopping urination. On physical examination, the prostate is enlarged to twice its normal size. One year ago, his serum prostate specific antigen (PSA) level was 6 ng/mL, and it is still at that level when retested. Which of the following is the most likely diagnosis?
(Normal range of PSA: Men aged 70 and above: 0 to 5.0 ng/mL for Asian Americans, 0 to 5.5 ng/mL for African Americans, and 0 to 6.5 ng/mL for Caucasians)
a) Prostate cancer
b) Hydrocele
c) Benign prostatic hyperplasia
d) Orchitis
The correct option is c) Benign prostatic hyperplasia (BPH). Based on the given information, the most likely diagnosis for this 72-year-old man is Benign prostatic hyperplasia (BPH).
Benign prostatic hyperplasia (BPH) is the most probable diagnosis for an otherwise healthy 72-year-old man who has had increasing difficulty with urination for the past ten years. BPH, prostate cancer, hydrocele, and orchitis are all distinct medical illnesses. BPH is a benign (non-cancerous) growth of the prostate gland's epithelial and stromal components.
The prostate, located beneath the bladder in males, produces semen components that help maintain the sperm in liquid form and prevent the immune system from attacking them. An enlarged prostate gland caused by BPH can impede the normal flow of urine, resulting in incomplete bladder emptying, weak urine flow, and other related symptoms. The prostate-specific antigen (PSA) blood test, which measures PSA levels in the blood, can help determine if the man is suffering from BPH or prostate cancer.
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Question 18 Which of the following statements about the female reproductive process is not true? O The luteal phase is always the last 14 days of the menstrual period. O Rebuilding the endometrium is under the control of prolactin. O Fertilization usually occurs in the uterine tube. O Menstrual flow is initiated by the decrease in secretion of female hormones.
The statement that "Rebuilding the endometrium is under the control of prolactin" is false. The hormones estrogen and progesterone regulate the growth and shedding of the endometrium.
The female reproductive process is a complex series of events that occur within the female reproductive system, leading to the possibility of pregnancy. However, there are several misconceptions or incorrect statements regarding this process. One such statement is that "Rebuilding the endometrium is under the control of prolactin." This statement is not true.
The endometrium is the lining of the uterus, which undergoes changes throughout the menstrual cycle. It thickens in preparation for potential implantation of a fertilized egg and sheds during menstruation if pregnancy does not occur. The rebuilding of the endometrium is primarily regulated by the hormones estrogen and progesterone, not prolactin.
During the menstrual cycle, estrogen levels rise, stimulating the growth of the endometrium. After ovulation, the ruptured follicle in the ovary forms the corpus luteum, which produces progesterone.
Progesterone helps further develop and maintain the endometrium, creating a suitable environment for a potential embryo to implant. If fertilization and implantation do not occur, the levels of estrogen and progesterone decline, leading to the shedding of the endometrium and the initiation of menstrual flow.
Prolactin, on the other hand, is a hormone primarily involved in the production of breast milk after childbirth. It plays a role in stimulating milk production and suppressing ovulation during breastfeeding. However, prolactin does not directly control the rebuilding of the endometrium.
In conclusion, the statement that "Rebuilding the endometrium is under the control of prolactin" is not true. The rebuilding of the endometrium is primarily regulated by the hormones estrogen and progesterone.
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Which of the following is FALSE? a. Biological membranes usually contain lipids, proteins, and carbohydrates. b. Proteins can allow specific molecules to cross membranes. c. Simple membranes are impermeable to other molecules. d. Membrane are held together noncovalently. e. Membranes are two molecules thick.
The false statement is (c) Simple membranes are impermeable to other molecules.
Simple membranes are not impermeable to other molecules. Biological membranes, including cell membranes, are selectively permeable, meaning they allow certain molecules to pass through while restricting the passage of others. This is facilitated by various mechanisms such as protein channels, transporters, and receptors embedded within the membrane. These proteins can facilitate the transport of specific molecules across the membrane, allowing for the necessary exchange of substances between the cell and its environment.
Therefore, option C is the false statement.
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2. Present a brief explanation of how electrical activity in the
human body interacts with electromagnetic waves outside the human
body to either your eyesight or your sense of touch.
Electrical activity in the human body interacts with electromagnetic waves outside the body to contribute to both eyesight and the sense of touch.
For eyesight, electromagnetic waves in the form of visible light enter the eye and interact with the specialized cells called photoreceptors located in the retina. When light waves reach the retina, they stimulate the photoreceptors, specifically the cones and rods. These photoreceptor cells convert the light energy into electrical signals through a process called phototransduction. The electrical signals are then transmitted through the optic nerve to the visual processing centers in the brain, where they are interpreted, resulting in the perception of vision.
Regarding the sense of touch, electromagnetic waves do not directly interact with the skin but rather with objects in the external environment. When you touch an object, pressure receptors in the skin called mechanoreceptors are stimulated. These mechanoreceptors convert the physical pressure applied to the skin into electrical signals, also known as action potentials. These electrical signals travel through sensory neurons to the somatosensory cortex in the brain, which processes and interprets the signals, allowing you to perceive the sense of touch.
In summary, electromagnetic waves in the form of visible light interact with photoreceptors in the eye, converting light energy into electrical signals for vision. For touch, electromagnetic waves indirectly interact by stimulating mechanoreceptors in the skin, which then generate electrical signals that are transmitted to the brain for the perception of touch.
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Mechanical food breakdown is an very important step in digestion. The first location where this takes place is the . which also referred to as the oral cavity. From there the bolus of food is transported by a long tune called the to the second place where mechanical breakdown takes place this organ is the This organ is flanked by two sphincters the upper one is called the sphincter and the lower one is called the sphincter. Contractions of the walls of this organ cause mixing of food with acid and other components into a substance called
Mechanical food breakdown is an important step in digestion. The first location where this takes place is the oral cavity, which is also referred to as the mouth. From there, the bolus of food is transported by a long tube called the esophagus to the second place where mechanical breakdown takes place. This organ is flanked by two sphincters, the upper one is called the cardiac sphincter and the lower one is called the pyloric sphincter.
Contractions of the walls of this organ cause mixing of food with acid and other components into a substance called chyme. Digestion is the process of breaking down food into smaller molecules that can be absorbed by the body. There are two types of digestion: mechanical and chemical digestion.
Mechanical digestion refers to the physical breakdown of food into smaller pieces by chewing and grinding it with teeth. The oral cavity is the first location where mechanical digestion takes place. Here, the food is crushed, ground, and mixed with saliva, which contains enzymes that break down carbohydrates.
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Which of the following is an example of how the Paris Agreement will impact a country's response to climate chang?
Olt will allow more international travel between France and other countries
Ot will create the plans that countries must follow and hold leaders responsible
Okt will provide the funds to all nations so that the citizens of the country will not be taxed
Oft will push the country to take stronger actions in their nationally determined contributions
The following option is an example of how the Paris Agreement will impact a country's response to climate change:
It will push the country to take stronger actions in their nationally determined contributions.
The Paris Agreement is a global treaty that aims to combat climate change and limit global warming to well below 2 degrees Celsius above pre-industrial levels. One of the key aspects of the agreement is the concept of nationally determined contributions (NDCs). Each participating country is required to submit their own NDC, which outlines their specific climate goals, targets, and strategies for reducing greenhouse gas emissions.By pushing countries to take stronger actions in their NDCs, the Paris Agreement encourages nations to enhance their efforts in combating climate change. This can include setting more ambitious emission reduction targets, implementing policies and measures to transition to cleaner energy sources, promoting sustainable practices, and investing in renewable energy and climate resilience initiatives.The Paris Agreement serves as a global framework that holds countries accountable for their actions and encourages continuous improvement in their response to climate change. By urging countries to strengthen their nationally determined contributions, it fosters a collective and collaborative effort towards addressing the global climate crisis.For more such question on Climate change
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QUESTION 17 Acetylcholine is released by all of these neurons, except O somatic motor neurons O all preganglionic neurons of the ANS O all sensory neurons O by the postganglionic parasympathetic neurons QUESTION 18 The effect of beta-blocker drugs (block beta-receptors) is to O decrease blood pressure O Increase blood sugar levels O increase blood pressure O decrease blood sugar levels
QUESTION 19 The secretions of the adrenal medulla act to supplement the effects of_____
Acetylcholine is released by all of these neurons except sensory neurons. Among the neurons, sensory neurons are not among the neurons that release acetylcholine.
These neurons receive information from sensory receptors throughout the body and convey this information to the spinal cord and brain for processing. The two types of sensory neurons are somatic and visceral sensory neurons.
Question 18:The effect of beta-blocker drugs (block beta-receptors) is to decrease blood pressure. Beta-blocker drugs block the effects of the hormone epinephrine (adrenaline), which causes the heart to beat faster and with more force. This reduces blood pressure.
Question 19:The secretions of the adrenal medulla act to supplement the effects of the sympathetic nervous system.
The sympathetic nervous system controls the body's "fight or flight" response, while the adrenal medulla secretes epinephrine (adrenaline) and norepinephrine (noradrenaline) to support this response by increasing the heart rate, blood pressure, and glucose levels in the bloodstream.
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3. How do the following influence the glomerular filtration rate? What is most important?
A.) Difference in pressure between blood in glomerular capillaries and filtrate in the Bowman’s space
B.) Difference in pressure between blood in peritubular capillaries and filtrate in the Bowman’s space
C.) Difference in pressure between blood in glomerular capillaries and filtrate in the distal tubule
D.) Difference in pressure between peritubular capillaries and filtrate in the proximal tubule
E.) Difference in pressure between afferent arterioles and efferent arterioles
The most important factor that influences the glomerular filtration rate is the difference in pressure between blood in glomerular capillaries and filtrate in the Bowman's space .The glomerular filtration rate is defined as the amount of blood plasma that passes through the glomeruli of the kidney's nephrons per unit time. It is typically expressed as a unit of volume per unit time (mL/min).Several factors influence the glomerular filtration rate (GFR), including the difference in pressure between blood in glomerular capillaries and filtrate in the Bowman's space.
The GFR is increased when the pressure difference is high and decreased when the pressure difference is low .The other factors listed in the question also influence the GFR, but they are less important than the pressure difference between blood in glomerular capillaries and filtrate in the Bowman's space. In general, the GFR is determined by the balance between the pressures that drive filtration and the pressures that oppose filtration .
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Albinism is due to a recessive alielea' An albino child is born to two parents who have normal ein pigmenation The genotype of the parents are? a. aa, Aa
b. aa, aa
c. Aa, Aa
d. all of these
The genotype of the parents who gave birth to an albino child while they have normal pigmentation is aa, Aa.
Albinism is a genetic condition in which a person lacks melanin pigment. As a result, individuals with albinism often have very light hair, skin, and eyes. It's caused by a recessive gene that a person inherits from their parents.Each person has two copies of the genes that control their physical characteristics. One of these genes is inherited from each parent. If a person has one copy of the albinism gene and one copy of a normal pigmentation gene, they will have normal pigmentation since the dominant normal pigmentation gene is expressed while the recessive albinism gene is not expressed.
A person with albinism, on the other hand, must inherit two copies of the recessive albinism gene to have the condition. The genotype of two parents who have a child with albinism is aa, Aa. The parents must have one copy of the albinism gene and one copy of a normal pigmentation gene (Aa). The child, on the other hand, must inherit one copy of the albinism gene from each parent (aa).Therefore, the correct answer is option A: aa, Aa.
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A person says "What if biological factors associated with maleness - such as testosterone levels - contribute to aggressive tendencies, which are then fostered and reinforced through social and cultural norms, which then further influence men's testosterone levels? This reciprocal and interactive influence of sex as biological and gender as socialization becomes very difficult to disentangle the root cause of any observed aggression differences between women and men." What is this person making reference to? A. The concept of "doing gender". B. The false dichotomy of sex and gender. C. The invisibility of gender D. The gendering of the X and Y chromosomes.
Biological and social factors, the person challenges the false dichotomy of sex and gender and highlights the need for a more nuanced understanding of human behavior.
The statement highlights the idea that biological factors associated with maleness, such as testosterone levels, may contribute to aggressive tendencies. However, these biological factors are not the sole determinants of aggression. The person suggests that social and cultural norms play a significant role in fostering and reinforcing aggressive behavior in men. This interaction between biological factors and socialization makes it challenging to identify the root cause of observed aggression differences between women and men.
The false dichotomy of sex and gender refers to the misconception that sex (biological differences) and gender (socially constructed roles and behaviors) are strictly separate and independent. This perspective fails to acknowledge the complex interplay between biology and socialization in shaping human behavior.
In this case, the person recognizes that testosterone levels, a biological factor associated with maleness, can influence aggression. However, they also emphasize that social and cultural norms play a crucial role in how aggression is expressed and reinforced within different genders. The reciprocal and interactive influence between biology and socialization makes it difficult to disentangle the root cause of observed aggression differences between women and men.
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10. In what way, if any, are the following affected by angiotensin II ?
A) blood pressure.
B) retention of sodium ions at the kidney.
C) water retention.
D) blood volume.
E) cardiac output
F) parasympathetic/sympathetic output
G) vasoconstriction/vasodiolation
H) thirst
Angiotensin II affects blood pressure, retention of sodium ions at the kidney, water retention, blood volume, cardiac output, vasoconstriction/vasodilation and thirst.Angiotensin II affects blood pressure, retention of sodium ions at the kidney, water retention, blood volume, cardiac output, vasoconstriction/vasodilation and thirst.
The following explains how angiotensin II is related to the listed variables:Blood pressure: Angiotensin II promotes the constriction of blood vessels, increasing peripheral resistance. It also prompts the production of aldosterone, which retains salt and water, increasing blood pressure.Retention of sodium ions at the kidney: Angiotensin II prompts the production of aldosterone, which retains salt and water, increasing blood pressure.Water retention: Angiotensin II promotes the production of aldosterone, which retains salt and water, increasing blood pressure.
Blood volume: Angiotensin II prompts the production of aldosterone, which retains salt and water, increasing blood pressure.Cardiac output: Angiotensin II promotes the constriction of blood vessels, increasing peripheral resistance.Vasoconstriction/vasodilation: Angiotensin II promotes the constriction of blood vessels, increasing peripheral resistance. Thirst: Angiotensin II stimulates the thirst centre in the hypothalamus.
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Skeletal muscle contraction is achieved via which type of receptor:
a.
Ligand-gated ion channels
b.
Tyrosine kinase-linked receptors
c.
G-protein-coupled receptors
d.
Nuclear receptors
e.
Non-protein drug targets
Skeletal muscle contraction is achieved via Ligand-gated ion channels. Receptors are defined as the cells that detect stimuli in the environment and convey the data to the Central Nervous System. Receptors can be categorised based on their anatomical position and function. Various types of receptors include Mechanoreceptors, Photoreceptors, Thermoreceptors, Chemoreceptors, and Nociceptors. Kinases are enzymes that add phosphate groups to other molecules, typically proteins, to modify their activity.
Kinases are involved in many signalling pathways that regulate cellular processes like metabolism, cell division, apoptosis, and differentiation. Kinases catalyse a variety of phosphorylation reactions, but protein kinases are the most well-known and widespread. Protein kinases are essential in signalling pathways for intracellular communication, allowing cells to respond to a variety of stimuli. Ligand-gated ion channels:Ligand-gated ion channels are a group of transmembrane proteins that regulate the flow of ions across the plasma membrane of neurons and other cells. Ligand-gated ion channels act as receptors for a variety of neurotransmitters, hormones, and other molecules that bind to specific sites on the channel's extracellular domain. Binding of the ligand to the receptor leads to conformational changes in the protein that open the channel, allowing ions to pass through. So, the correct answer is Option A: Ligand-gated ion channels.
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question 2 solve the following multiple choice:
a.Which of the following statements regarding the risks of low level exposure to carcinogens is true?
options:
-Any exposure to a carcinogen represents a finite risk
-Some carcinogens appear to have a threshold dose
-There is a threshold dose for all carcinogens
b. A person enters an industrial building where platinum salts are being processed and within in minutes suffers a major life-threatening asthma attack. The reason for the immediacy and severity of this response was probably:
Platinum can trigger a rapid release of histamine from macrophages
The person was already an asthmatic due to other types of exposure (such as dust or pollen) and was cross-sensitive to platinum as a result
The person had previously been sensitised to platinum salts and as a result there were high levels of platinum antigen-specific IgE on the surface of masts cells in the respiratory tract
c. Which of the following statements about the value of in-vivo toxicity tests is true?
In-vivo tests are unecessary because in-vitro tests are available
In-vivo tests are imperfect but are a necessary way of predicting the toxicity of substances such as new drugs, food additives and pesticides
In-vivo tests have no relevance to human risk assesment
d. Immune tolerance is best defined as:
the mechanism by which the immune system recognises the self and does not attack it
hypersensitivity
immunosupression
e. All of the following individual chemicals are known to be capable of causing peripheral neuropathy upon prolonged exposure except:
Carbon disulfide
Acrylamide
Methyl ethyl ketone
question 3 : what is Ames test and how does it work ?
A person enters an industrial building where platinum salts are being processed and within in minutes suffers a major life-threatening asthma attack.
The reason for the immediacy and severity of this response was probably: The person had previously been sensitised to platinum salts and as a result, there were high levels of platinum antigen-specific IgE on the surface of masts cells in the respiratory tract.Ans: b. The person had previously been sensitised to platinum salts and as a result, there were high levels of platinum antigen-specific on the surface of masts cells in the respiratory tract.
The format of multiple-choice questions includes a problem followed by different choices. The candidate has to choose the correct option that best fits the situation or problem. Ames test is a test used to evaluate the potential of a substance to induce a mutation in DNA. It was invented by Bruce Ames, a scientist, in 1971, and since then, it has become one of the most commonly used short-term tests for identifying chemical carcinogens.
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REQUIRED: 5. There are two broad categories of hormones, as we discussed them in class: amino acid derivatives and steroid derivatives. Please list three differences between the two groups. Feel free to make a table. (2 pts.)
The table below highlights the differences between amino acid derivatives and steroid derivatives:
1. Chemical composition: They are made up of amino acid molecules that are either modified or combined with other molecules. Steroid hormones have a cholesterol-derived chemical composition.
2. Solubility: They are water-soluble. Steroid hormones are lipid-soluble.
3. Receptor location: They bind to receptors on the surface of the target cell. They bind to receptors inside the target cell. Table demonstrating the differences between amino acid derivatives and steroid derivatives
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what is phenotype, homozygous, and heterozygous in a kids definition?
Genetics is a field of study in Biology that explores how traits are inherited and expressed in living organisms, including humans, animals, and plants. Knowing key terminology can help us deepen our understanding of the topic.
Phenotype: Refers to the observable or physical traits of an organism. For example, if we are looking at a human who is tall and has black hair, we can say that the phenotype for that human is tall for the height gene and black for hair color.
Homozygous: When an individual has two identical copies of a gene for a particular trait. If homozygous, the genes inherited from the mother and father are exactly the same. For example, if T = tall and t= short, a homozygous individual would be either TT or tt for their height gene.
Heterozygous: When an individual has two different copies of a gene for a particular trait. If heterozygous, the genes inherited from the mother and father will be different. For example, if B = blue hair and b = brown hair, a heterozygous individual would have Bb for their hair color gene.
9. When a cold thermoreceptor encounters cold temperature, it signals this by: A. Decreasing its firing rate B. Increasing its firing rate C. Maintains its firing rate D. None of the above
Cold thermoreceptors are the sensors that respond to the changes in temperature. These receptors are found in skin, lungs, and skeletal muscle. When they encounter cold temperature, they signal this by increasing their firing rate. The temperature threshold for the cold receptors is about 15 degrees Celsius.
Cold receptors belong to the TRP ion channel family, which consists of six different subtypes. TRP channels are activated by a variety of stimuli such as temperature, mechanical stress, osmotic pressure, and ligands. Cold receptors signal the brain about the cold environment by firing nerve impulses through sensory neurons.
The neurons from the skin activate the dorsal root ganglia, which in turn stimulate the spinal cord. From the spinal cord, the sensory information is transmitted to the brain for interpretation. When the temperature of the environment decreases, the cold receptors become activated and increase their firing rate.
As a result, the sensory neurons produce more action potentials that are then transmitted to the brain. This is interpreted as a feeling of coldness. Therefore, the correct option is B) Increasing its firing rate.
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1. Which of the following senses rely on chemoreceptors?
1. Taste and Vision
2. Smell and Taste
3.Taste and Hearing
4. Smell and Hearing
The senses that rely on chemoreceptors are Smell and Taste. The correct option is 2.
Chemoreceptors are sensory receptors that respond to different types of chemical substances. They are a type of sensory receptor that is involved in sensing chemicals in our environment. The chemoreceptors of the human body include olfactory receptors (in the nose) and taste receptors (on the tongue).These receptors can identify the chemical composition of substances that we come into contact with in the environment. When it comes to taste and smell, these chemoreceptors are involved in detecting the flavor and scent of substances. In this sense, chemoreceptors play an important role in our perception of taste and smell. So, the correct option among the given options is (2) Smell and Taste.
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Activity 2 Data Table 2. Protein Test Test tube 1: water + Biuret reagent Tests Test tube 2: water + albumin solution + Biuret reagent Test tube 3: water + potato starch solution + Biuret reagent Additional food item (identify): bread Additional food item (identify): goat milk Additional food item (identify): olive oil Results (+ or -) Data Table 5. Modeling Intestinal Digestion of Starch Tests Test tube 1: starch + pancreatin powder + iodine-potassium iodide at room temperature Test tube 2: starch + pancreatin powder + iodine-potassium iodide at 80-90°C Test tube 3: starch + pancreatin powder + iodine-potassium iodide at 35-40°C Results (+ or -)
Data Table 2: Protein Test: In Test tube 1, the protein test was conducted by adding Biuret reagent to water. The result was negative (-).
In Test tube 2, the protein test was conducted by adding Biuret reagent to the albumin solution. The result was positive (+). In Test tube 3, the protein test was conducted by adding Biuret reagent to the potato starch solution. The result was negative (-). Additional Food Item (Identify):In Test tube 4, the protein test was conducted by adding Biuret reagent to the bread. The result was negative (-).In Test tube 5, the protein test was conducted by adding Biuret reagent to the goat milk. The result was positive (+). In Test tube 6, the protein test was conducted by adding Biuret reagent to the olive oil. The result was negative (-).
Data Table 5: Modeling Intestinal Digestion of Starch:Test tube 1 contained starch, pancreatin powder, and iodine-potassium iodide and was kept at room temperature. The result was negative (-).Test tube 2 contained starch, pancreatin powder, and iodine-potassium iodide and was kept at 80-90°C. The result was positive (+).Test tube 3 contained starch, pancreatin powder, and iodine-potassium iodide and was kept at 35-40°C. The result was negative (-).Note: The positive and negative results signify the presence or absence of a particular substance in the given food sample.
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Notice that in the alignment table, the data are arranged so each globin pair can be compared.
b. Notice that the cells in the lower left half of the table are blank. Using the information already provided in the table, fill in the missing values. Why does it make sense that these cells were left blank?
The cells in the lower left half of the alignment table are left blank because they represent comparisons between the same sequences. In other words, they are self-comparisons.
When aligning sequences, it is important to compare each sequence with every other sequence in order to identify similarities and differences.
However, when comparing a sequence with itself, the result will always be identical.
Therefore, filling in these cells with the same sequence would be redundant and not provide any additional information.
By leaving these cells blank, we can focus on the unique comparisons between different sequences, which are more informative for understanding the relationship and similarities between the globin pairs. This allows us to efficiently organize and analyze the data without unnecessary repetition.
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