Ergonomics is an important consideration for all computing devices.
Ergonomics is important because your musculoskeletal system is impacted while you're performing a duty and your body is stressed by an imbalanced stance, unusual temperature, or repeated development. The Function of Ergonomics at Work maintains workplace ergonomics as a top concern, such as reducing screen glare, decreasing movement, enhancing posture, and placing equipment at ideal statures and locations that increase effectiveness and employee commitment The goal of ergonomics is to reduce accidents and injuries. A strategy for improving workplace ergonomics eliminates hazards that can result in musculoskeletal injuries and takes into account enhanced human performance and efficiency.
The complete question is:
Ergonomics is an important consideration _____________.
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what is alternation of generations? does meiosis occur in the sporophyte or the gametophyte? which is haploid, the sporophyte or the gametophyte? compare the relative sizes of the sporophytes and gametophytes in nonvascular plants. compare the relative sizes of the sporophytes and gametophytes in vascular plants.
In plants, the gametophyte stage and the sporophyte stage alternate in order to produce new generations.
Do sporophytes or gametophytes undergo meiosis during alternation of generations?The meiosis of a few cells in the diploid body results in the formation of spores. A new haploid generation is created as a result of the spores dispersing. A haploid gametophyte and a diploid sporophyte alternate during the ensuing life cycle, which is known as alternation of generations.
What does generational alternation mean?Asexual and sexual phases of an organism's life cycle alternate, or metagenesis, also known as heterogenesis or alternation of generations in biology. Both physically and occasionally chromosomally, the two phases or generations can be distinguished from one another.
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an individual living thing that is made of cells, uses energy, reproduces, responds, grows, and develops
An individual living thing that is made of cells, uses energy, reproduces, responds, grows, and develops is called an organism.
Organisms are defined as living creatures. All living things consist of one or more cells, respond to their environment, develop, reproduce, and maintain a stable internal environment in addition to needing energy to carry out life functions.
An individual living creature that maintains its life through organs that each serve a different purpose but are interdependent.
All living things share a number of essential traits or abilities, such as order, environmental sensitivity or responsiveness, reproduction, growth and development, regulation, homeostasis, and energy processing. When taken as a whole, these eight qualities help to define life.
The existence of protoplasm in an organism's cells is the primary indicator that it is alive. Each type of cell, including eukaryotic and prokaryotic ones, has protoplasm. It gives the organelles a neutral platform on which to carry out their respective tasks.
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Impulse conduction is fastest in neurons that are(a) Myelinated.(b) Motor.(c) Unmyelinated.(d) Sensory.
Impulse conduction is fastest in neurons that a. Myelinated
The nervous system is the coordination system in charge of controlling all body activities after receiving impulses and manipulating them. Impulse is a stimulus in the form of an electric current that is forwarded to the spinal cord.
The mechanism of impulse transmission occurs by conduction which involves the pumping of Na+ and K+ ions through a semipermeable membrane.
The part of the nerve cell that transmits stimuli is the neuron where in the long part, namely the axon, there is a myelin sheath which functions to accelerate stimulation. When action potentials occur, myelin speeds up the transmission of nerve impulses by assisting in charge jumping. The speed of conduction of an impulse will increase in direct proportion to the increase in the diameter of the nerve.
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In bacteria, binary fission can be modeled in?
A. three stages.
B. one stage.
C. two stages.
D. four stages.
Binary fission may be modeled in terms of four states. Option (D) is suitable as a consequence.
The actions of microorganismsSome bacteria aid in food digestion, eliminate disease-causing cells, and supply the body with vital vitamins. Healthy foods like yogurt and cheese are produced using bacteria as well. However, contagious microorganisms can get you sick. In your body, they procreate swiftly.
What causes bacteria, and what does it do?One simple but intricate cell makes up a bacteria. It is capable of surviving on its own, both within and outside the body. Most germs don't pose a threat. In truth, we have a lot of bacteria on and inside of us, especially with the stomach where they aid in digestion. However, certain germs can lead to illnesses.
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when comparing dna and rna, two nucleic acids, which statement is accurate about the function(s) of these molecules?
The comparing DNA and RNA states contain codes contributing to protein production. DNA remains in the nucleus, while RNA more directly contributes to protein
DNA, also known as deoxyribonucleic acid, serves as the initial blueprint for protein production in cells. Deoxyribose, phosphates, and a specific arrangement of the nitrogenous bases adenine (A), guanine (G), cytosine (C), and thymine are all found in DNA (T).
All living cells include the significant nucleotide ribonucleic acid, which is found in long chains. Its primary function is to serve as a messenger, carrying DNA's instructions for regulating protein synthesis. Ribose, phosphates, and the nitrogenous bases adenine (A), guanine (G), cytosine (C), and uracil are all found in RNA (U). The nitrogenous bases A, G, and C are shared by DNA and RNA. Uracil and thymine are often only found in DNA and RNA, respectively.
Hence, nucleic acid is present in the nucleus in the cell.
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higher expression of a gene protects a plant under heat stress. in a very hot summer, what kind of mutation will most likely happen?
Mutation that will most likely happen are:
A. Disruption of the gene
B. Duplication of the gene
C. Change in the promotor that increases expression of the gene.
A gene is the fundamental physical and purposeful unit of heredity. Some genes act as instructions to make molecules referred to as proteins. but, many genes do now not code for proteins.
Our genes incorporate instructions that inform your cells to make molecules referred to as proteins. Proteins perform various features on our body to keep you healthy. Every gene includes commands that determine your functions, together with eye color, hair shade and height.
Few genes act as commands to make molecules referred to as proteins.In human beings, genes vary in length from a few hundred DNA bases to extra than 2 million bases.
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Replication of the lagging strand of dna is accomplished by adding new __________. This creates ______________ on the lagging strand.
Replication of the lagging strand of DNA is accomplished by adding new RNA primers. This creates Okazaki fragments the lagging strand.RNA primers.
Deoxyribonucleic acid is a polymer composed of polynucleotide chains that coil spherically each one-of-a-kind to form a double helix. The polymer includes genetic instructions for the development, functioning, boom, and replica of all seemed organisms and lots of viruses.
In all dwelling things, DNA is vital for an inheritance, coding for proteins, and offering instructions for life and its tactics. Human cells commonly consist of 23 pairs of chromosomes, for a complete forty-six chromosomes in every cell.
Most DNA is positioned within the cell nucleus. Mitochondria are structures within cells that convert the power from meals right into a shape that cells can use.
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Which of the following general mechanisms appear to be involved in the formation of cancer cells?
Which of the following general mechanisms appear to be involved in the formation of cancer cells?
A. RNA failure, DNA phosphorylation, phosphorylation of adenyl cyclase
B. inversions, operon formation, methylation
C. transdetermination, mutation, allosteric interactions
D. genomic instability, DNA repair failure, chromatin modifications
E. suppression, tabulation, projection
Genomic instability, DNA repair failure, chromatin modifications are generally mechanisms appear involved in formation of cancer. Then D should be appropriate.
What are the 3 steps of cancer formation?The three-stage theory of carcinogenesis is one of the most common explanations for the development of cancer. This theory divides cancer development into three stages, are: initiation, promotion, and progression.3 factors that contribute to cancer are, age, weight, exposure to carcinogens, and genetics can increase the risk of developing cancer.Genes, the fundamental building blocks of inheritance, can change in ways that result in cancer. Chromosomes are long, tightly packed DNA strands where genes are organized. Cancer is a genetic disease, meaning that it results from alterations in the genes that regulate certain aspects of how our cells behave, most notably how they grow and divide.Learn more about genetic disease here: brainly.com/question/2974335
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Which of the following is an example of discontinuous distribution?
(A) Whales
(C) Dipnoi
(B) Molluscs
(D) Birds
Answer:
A
Explanation:
because there are several types and mode of whales
a client has been experiencing a decrease in serum calcium. after diagnostics, the physician proposes the calcium level fluctuation is due to altered parathyroid function. what is the typical number of parathyroid glands?
There are typically four parathyroid glands in each person.
The thyroid gland contains four parathyroid glands, which secrete the parathyroid hormone (PTH). Another hormone, calcitonin, is secreted by so-called C cells that are scattered throughout the thyroid gland, parathyroids, and thymus. The preservation of calcium homeostasis is significantly influenced by both hormones.
PTH, a polypeptide secreted in response to hypocalcemia, increases renal calcium reabsorption, mobilizes calcium from bones by stimulating osteoclastic activity, stimulates the absorption of calcium from the small intestine in the presence of sufficient amounts of vitamin D, and lowers plasma inorganic phosphate levels by inhibiting renal phosphate reabsorption.
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A Venn diagram comparing DNA and Genes
DNA and genes are both made up of the same nucleotides, and the gene is present on the DNA, but not all the DNA is in the gene segment. The gene codes for a certain character.
What are the similarities and differences between DNA and genes?The DNA has the gene, and the exons parts of the gene code for the trait, while the DNA and gene are both made up of nucleotides. The gene undergoes the transcription process for the expression of the trait, and the genes present in the euchromatin do this. The heterochromatin can't take part in this transcription process.
Hence, DNA and genes are both made up of the same nucleotides, and the gene is present on the DNA, but not all the DNA is in the gene segment. The gene codes for a certain character.
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4. for the ddel-digested, mutant beta-globin sequence, how many nucleotides are in each fragment? how many basepairs are in each fragment? remember that a base pair includes two bound nucleotides. if a base is not paired because of a sticky end, do not count it.
The nucleotide in each fragments are 6 in the ddel-digested, mutant beta-globin sequence.
So as their are 6 nucleotides in every fragment way there need to be three pairs for Ddel digested, wild kind beta globin sequence. And additionally for mutant beta globin sequence. a base isn't paired due to a sticky end, do now no longer remember it.
This countdetermines the approximate length of the fragment. May it will likely be helpful. So as their are 6 nucleotides in every fragment way there need to be three pairs for Ddel digested, wild kind beta globin sequence.
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if a male undergoes a vasectomy, which of the following can no longer take place?
If a male undergoes a vasectomy, passage of sperm cells from the epididymis to the urethra. That is option A.
What is vasectomy?Vasectomy is defined as the surgical procedure that is being carried out to ligate the tube the transports sperm from the epididymis to the urethra during ejaculation.
The importance of vasectomy include the following:
It doesn't have any effect on the hormonal level of the male or general health.It can serve as a permanent method of birth control.The disadvantages of vasectomy include the following:
It does not protect against transmitted diseases.it may not be retrieved once the procedure has been carried out.Therefore, when a male individual undergoes vasectomy, they won't be able to pass sperm from epididymis to the urethra for ejaculation.
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Complete question:
If a male undergoes a vasectomy, which of the following can no longer take place?
a.) passage of sperm cells from the epididymis to the urethra.
b.) passage of sperm cells from the seminiferous tubules to the rete testes
c.) passage of sperm cells from the rete testes to the epididymis duct
d.) passage of sperm cells from the epididymis duct to the epididymis tail
5. if 5.0 w of 290 nm uv light is absorbed by dna in your skin during a tanning parlor session lasting 1 hour (3600 seconds), and if the quantum yield for producing thymine dimers (major cause of skin cancer) is 0.0001, what would be the number of moles of thymine dimers produced?
If the quantum yield for producing thymine dimers (major cause of skin cancer) is 0.0001, then the number of moles of thymine dimers produced is 1.2 * 10^-9 moles.
How to calculate the number of moles of thymine dimers produced?The mole is defined as the amount of substance that contains as many as elementary entities as there are atoms in exactly 12g of carbon-12. Mole is also the SI unit for the amount of substance.
Energy E = n * h * c / λ
Where E = 5w = 5J/s
n = no of molecules
h = planck's constant (6.6 * [tex]10^{-34}[/tex])
c = 3 * [tex]10^{8}[/tex](from literature)
λ = 290 * [tex]10^{-9}[/tex] (wavelength)
So, now let's use the formula
5 = [tex]\frac{n * 6.6 * 10^{-34} * 3 * 10^{8} }{290 * 10{-9} }[/tex]
n = 7.323 * [tex]10^{18}[/tex]
Moles of photon = 7.323 * 10^18 / Na
Na = 6.023 * 10^23 atoms (from literature)
= [tex]\frac{7.323*10^{18} }{6.023*10^{23} }[/tex]
= 1.22 * [tex]10^{-5[/tex]
Now, using the quantum yield formula
Quantum yield = moles of thymine dimer produced / moles of photon absorbed
0.0001 = moles of thymine dimer produced / 1.22 * [tex]10^{-5[/tex]
moles of thymine dimers produced = 0.0001 * 1.22 * [tex]10^{-5[/tex]
= 1.2 * [tex]10^{-9}[/tex] moles
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Lipids are large complex molecules called
These are referred to as macromolecules. The majority of macromolecules are polymers, which are lengthy chains of monomeric components.
The structure and function of all four kinds of big biological molecules will next be investigated: carbohydrates, lipids, proteins, and nucleic acids.
Large organic molecules, known as macromolecules in biological systems, can contain hundreds or thousands of atoms. The majority of macromolecules are polymers,
which are molecules made up of a single unit (monomer) repeated multiple times. Four of the six electrons in carbon are accessible for bonding with other atoms.
The structure and function of all four kinds of big biological molecules will next be investigated: carbohydrates, lipids, proteins, and nucleic acids.
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drag the appropriate trnas to the binding sites on the ribosome to show the configuration immediately before a new peptide bond forms. note that one of the binding sites should be left empty.
P (peptidyl), A (aminoacyl), and E (exit) sites are three locations on the ribosome where tRNA can bind. At the P site is a binding for the initiator methionyl tRNA. The next aminoacyl tRNA is paired with the second codon of the mRNA to bind to the A site, which is the first step in elongation.
Three RNA binding sites, A, P, and E, can be found on ribosomes. The A-site binds a free tRNA, the P-site a peptidyl-tRNA (a tRNA bound to the polypeptide chain), and the E-site (exit) binds an aminoacyl-tRNA or termination release factor.
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improper reduction or immobilization of a fractured femur can result in which outcome after cast removal?
After cast removal, improper reduction or immobilization of a fractured femur can result in malalignment of the fracture, pain, stiffness, limited range of motion, and decreased strength in the affected limb.
Improper reduction or immobilization of a fractured femur can result in malunion. Malunion is a condition where the fracture fragments heal in a position that is different from their original alignment, resulting in a deformity.
Step by step, the outcome of improper reduction or immobilization of a fractured femur is as follows:
1. The fracture fragments fail to heal in the correct alignment due to improper reduction or immobilization of the fractured femur.
2. As a result, the fracture fragments heal in a position that is different from their original alignment.
3. This creates a deformity in the bone, which is known as malunion.
4. After cast removal, the patient may experience pain, stiffness, or deformity at the fracture site due to the malunion.
5. In some cases, the patient may require additional surgery to correct the deformity caused by the malunion.
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what event occurred during this cycle of meiosis
Pairing of homologous chromosomes occurs during the cycle of meiosis.
There are two divisions in meiosis; the first division is meiosis I: the number of cells is doubled but the number of chromosomes is not. This results in 1/2 as many chromosomes per cell. The second division is meiosis II: this division is like mitosis; the number of chromosomes does not get reduced.
In meiosis, DNA replication is followed by two rounds of cell division to produce four daughter cells, each with half the number of chromosomes as the original parent cell. The two meiotic divisions are known as meiosis I and meiosis II.
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Select the correct answer.
The images show two different types of Galapagos tortoises that scientists believe descended from the same species. The first type (left) are found on islands that have high vegetation and few grasses. The second type (right) are found on an island that has large amounts of grasses and low-lying shrubs. What explains the type of turtle found on the islands with high vegetation?
The image shows two different types of Galapagos tortoises. The tortoise on the left has a vegetarian and few grasses. The tortoise on the right has a large number of grasses and low-lying shrubs.
A.
The environment triggered a gene mutation in neck length in order to help the turtle survive.
B.
Mutations are random, so it is by chance that turtles with longer necks live on these islands.
C.
Turtles with genes for long necks had a better chance of surviving to reach reproductive age.
D.
Turtles with short necks completely lacked adaptations for finding food, so they died off.
The explanation for the type of turtle found on the islands with high vegetation is that Turtles with genes for long necks had a better chance of surviving to reach reproductive age.
The correct option is C.
What is adaptation?Adaptation is the process by which organisms adapt to their environment as a result of the development of special features or structures that help them to survive in their environment.
Then turtles with genes for long necks were better suited to obtain food from the high vegetation. Hence, they were able to survive.
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with larger brains comes more costly offspring and increased parenting effort from fathers. therefore, what other characteristic do we expect to evolve with this set of traits?
Human genetics refers to the genetic research that is exclusively focused on humans and their genetic analyses, including genetic illnesses and human pedigree analysis.
Human genetic knowledge allows humans to discover many dangerous genetic disorders, including prenatal genetic anomalies.
Cooperation is an evolutionary feature that may be precisely defined through group selection.
Group selection is a characteristic that improves a population's survival rate and fitness. The cooperative character of ancient people developed for hunting, gathering, and living in harmony.
Humans' cooperative conduct allows them to evolve together by assisting one another in the face of adversity.
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The benificial mutrients help in evolution . why?
Answer:
Well, nutrients can help give you protein and vitamins, So you can do your daily things like walking, running, or doing what you are doing right now typing on your computer.
Explanation:
Are the ion channels' pore-forming transmembrane domains hydrophobic alpha helixes?
The ion channels' pore-forming transmembrane domains hydrophobic alpha-helices.
By using infrared spectroscopy, the structure of the pore-forming transmembrane region of the Torpedo nicotinic acetylcholine receptor has been studied.
Affinity-purified receptors treated with proteinase K or proteinase pronase have their extramembranous domains (about 75 percent of the protein mass) digested, leaving behind hydrophobic membrane-imbedded peptides that range in size from 3-6 kDa and are immune to peptide (1)H/(2)H exchange.
The transmembrane domain preparations' infrared spectra show reasonably strong and symmetric amide I and amide II band contours, accordingly centred about 1655 and 1545 cm(-)1 in (1)H(2)O and (2)H(2)O.
The amide I band is extremely reminiscent to the amide I bands seen in the spectra of alpha-helical proteins, including myoglobin and bacteriorhodopsin, which lack beta structure and display far less beta-sheet character than seen in proteins with a lesser as 20% beta sheet.
With the residual peptides presumably acquiring prolonged and/or turn structures at the bilayer surface, curve-fitting predicts that 75–80% of the peptides have an alpha helical nature.
Transmembrane alpha-helices aligned perpendicular to the surface of the bilayer are aligned with infrared dichroism spectra. The nicotinic receptor, the most extensively researched ligand-gated ion channel, is thought to have five bundles of four transmembrane alpha-helices in its transmembrane domain.
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Most amphibians have an aquatic larval form with _____ and a terrestrial adult form with _____.
lungs; gills
gills; gas exchange through the skin
lungs; lungs
gills; lungs
gas exchange through the skin; lungs
Most amphibians have an aquatic larval form with gills and a terrestrial adult form with lungs.
What about amphibians?Animalia's Chordata phylum is where the species that make up the class Amphibia are classified. These multicellular animals can be found in both the sea and on land. There are roughly 3000 species in this class.
Small animals called amphibians require water or a wet environment to exist. This category includes frogs, toads, salamanders, and newts. They all have extremely thin skin that allows them to breathe and absorb water. Amphibians have unique skin glands as well, which generate helpful proteins.
Frogs, toads, salamanders, newts, and caecilians are examples of the group of cold-blooded vertebrates known as amphibians (wormlike animals with poorly developed eyes).
Correct option: gills, lungs
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which of the following types of cells, found in connective tissue, are the most abundant?
The most prevalent form of connective tissue cells are fibroblasts. Both fibers and an amorphous ground substance are produced by them.
Only the oval nuclei are typically visible. The aforementioned fibers are found in close proximity to these cells. Fibroblasts are visible in the tendon as elongate nuclei situated in between collagen fibers.
Although they are often categorized among the connective tissues, skeletal tissues, cartilage, and bone have highly specific structures and functions that are discussed in Chapter 5. Similar to the general connective tissues, these specialized varieties are distinguished by their extracellular matrix, which constitutes the bulk of the tissues and is in charge of their characteristics.
Compared to cells found in ordinary connective tissues, resident cells are unique. Both mature chondrocytes and chondroblasts, which produce the matrix, are found in cartilage. Osteoblasts create the matrix of the bone. Osteocytes, their mature progeny, are embedded within the matrix, which they assist in mineralizing, renewing, and maintaining.
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QUESTION - Which cell type is most abundant in connective tissue?
A. Macrophages
B. Adipocyte
C. White blood cell
D. Melanocyte
E. Fibroblast
Which choice best describes the antimicrobial activities in the mouth?
a. IgA secreted into the mucus coating prevents pathogen binding.
b. production of enzymes that degrade bacterial peptidoglycan.
c. hydrochloric acid denatures proteins and killing many microbes.
The antimicrobial activities in the mouth are hydrochloric acid denatures proteins and killing many microbes.
The capability of an hydrochloric acid activating pathogen-killing compounds is not a part of insect immunity,There has recently been an increase in interest in trehalose metabolism for therapeutic applications due to trehalose's relevance in numerous pathogenic species.The most significant biosynthetic process is the enzyme TPP (trehalose-6-phosphate phosphatase) (OtsAB).
Here, five important nematode and bacterial pathogens' recombinant TPPs, including three new members of this protein family, are compared for their enzyme characteristics.
The kinetics of the hydrolysis of trehalose-6-phosphate show that all five enzymes display burst-like kinetic behaviour, which is characterised by a decrease in enzymatic rate beyond the pre-steady state.
The observed super-stoichiometric burst amplitudes can be explained by many global conformational changes that occur in members of this enzyme family during substrate processing.
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in gel electrophoresis, dna fragments are separated based on their: how many thymine bases are in the fragment. size. charge. sequence. how many adenine bases are in the fragment.
In gel electrophoresis, the DNA fragments are separated based on their size.
what do you know about gel electrophoresis?
A laboratory technique called gel electrophoresis is used to divide combinations of DNA, RNA, or proteins based on their molecular sizes. In gel electrophoresis, the molecules that need to be separated are forced through a gel that has tiny pores by an electrical field. The speed at which the molecules move through the pores in the gel is inversely proportional to their lengths. So, this indicates that a smaller DNA molecule will move through the gel further than a larger DNA molecule.
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dtc providers such as 23andme can provide consumers with their genetic susceptibilities to different complex genetic diseases. the genetic information is based on:
Risk variables identified by GWAS results serve as the foundation for the genetic data.
Exactly what does DTC in genetic testing mean?People can obtain their genetic data through direct-to-consumer genetic testing, which does not necessarily require the involvement of a healthcare professional or health insurance provider. Direct-to-consumer genetic tests are already available from a large number of companies for a range of uses.
What genetic data is offered by 23andMe?23andMe analyzes your DNA using genotyping once you submit a saliva sample. This implies that we focus on regions of your genome that are known to vary from person to person. Then, using those findings, we create customized genetic reports on a range of topics, including features, genetic health concerns, and ancestral composition.
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Which of the following is
NOT true of energy?
A. Energy can be transformed.
B. Energy can be thrown away.
C. Energy can be recycled.
Answer:
B. Energy can be thrown away.
Explanation:
Queston 25 What feature of fats makes them hydrophobic?
a. Fats are large molecules
b. Fats are mostly made of carbon and hydrogen which are nonpolar;
c. Fats contain many oxygen atoms:
d. Fats include one glycerol molecule
Question 26 All of the following are types of lipids EXCEPT:
a. enzymes
b. steroids
c. phospholipids
d. triglycerides
Fats generally contain a long hydrocarbon chain, which is hydrophobic. This nonpolar chain is composed of carbon and hydrogen atoms, which do not mix well with water. correct option (a).
All of the following (enzymes ,steroids , triglycerides )are types of lipids EXCEPT (c) phospholipids.
What Does Hydrophobic Mean?
Hydrophobic is a property of a substance that repels water. It means lacking affinity for water, and tending to repel or not to absorb water. Hydrophobic molecules tend to be non-polar molecules and group together.
What is a lipids and its function?
Lipids are fatty compounds that perform a variety of functions in your body. They're part of your cell membranes and help control what goes in and out of your cells. They help with moving and storing energy, absorbing vitamins and making hormones. Having too much of some lipids is harmful.
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achondroplasia, a form of hereditary dwarfism, is an example of a(n) . a. autosomal dominant disorder b. autosomal recessive disorder c. x-linked disorder d. heritable change in chromosome structure e. heritable changes in chromosome number
Achondroplasia, a form of hereditary dwarfism, is an example of an autosomal dominant disorder.
It is a genetic disorder in which an affected person will have short height, prominent forehead, enlarged head, frequent ear infection and sleep apnea. It is caused by mutation in fibroblast growth factor receptor 3 (FGFR3) gene. It is found in chromosome 4. Gene is responsible for the production of protein fibroblast growth factor receptor 3. Protein responsible for production of collagen. When the FGFR 3 gene gets mutated, the FGFR 3 protein's interaction with the growth factor is interrupted leading to disruption in bone production. Since it's an autosomal dominant single mutant allele is enough to cause disease, presence of two mutant alleles is fatal. Persons with this condition have a 50% chance to transfer it to their offspring.
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