Selective estrogen-receptor modulators such as tamoxifen and aromatase inhibitors reduce the proliferation of certain types of breast cancer cells by O blocking their uptake of estrogen. O degrading the blood vessels that supply them with estrogen. O increasing ovarian production of progesterone. O increasing ovarian estrogen production

Answers

Answer 1

Selective estrogen-receptor modulators such as tamoxifen and aromatase inhibitors reduce the proliferation of certain types of breast cancer cells by degrading the blood vessels that supply them with estrogen.

The statement: "Selective estrogen-receptor modulators such as tamoxifen and aromatase inhibitors reduce the proliferation of certain types of breast cancer cells by degrading the blood vessels that supply them with estrogen" is a true statement. Estrogen stimulates the growth of certain types of breast cancer cells. Aromatase inhibitors block the production of estrogen in body fat and muscle tissue, which are alternative sources of estrogen after menopause.

Tamoxifen is a selective estrogen receptor modulator (SERM) that prevents estrogen from binding to the estrogen receptor in the cell, thereby preventing the growth of the cancer.

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Related Questions

Each division of the PNS has specific functions. Sorteach function into the bin that correctly matches it with the division of the PNS.
(View Available Hintis) 1. Taste 2. Kidney pain 3. Innervation of smooth muscle 4. Skeletal muscle innervation 5. Temperature of skin 6. Innervation of heart 7. Autonomic nervous system 8. Chemical change of blood 9. Stretch of stornach 10. Proprioception of limbs 11. Touch and pressure 12. Hearing a) Somatic sensory b) Visceral sensong c) Somatic motor d) Visceral motor

Answers

Functions of the different divisions of the Peripheral Nervous System (PNS) are given below:

Somatic sensory

1. Touch and pressure

2. Proprioception of limbs

3. Taste

4. Temperature of skin

Somatic motor

1. Skeletal muscle innervation

Visceral sensory

1. Chemical change of blood

2. Kidney pain

3. Stretch of the stomach

Visceral motor

1. Innervation of smooth muscle

2. Innervation of the heart

3. Autonomic nervous system

The PNS has two divisions, namely the somatic nervous system and the autonomic nervous system.

Somatic Nervous System includes the somatic sensory and somatic motor.

Somatic Sensory nerves carry information from the skin, joints, skeletal muscles, and special senses like sight and hearing.

Somatic Motor nerves, on the other hand, innervate skeletal muscles that are responsible for voluntary muscle contractions, that enable the body to move as per the instructions of the brain.

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18 3 points The filtering unit of the nephron is: A renal corpuscle B.renal tubules C. Nephron D. Bowman's capsule. O E. endothelial-capsular membrane. Ёооооо 19 3 points Urine is derived from filtering blood plasma, and is formed by which of the following functions of the nephron(s)? O A. Glomerular filtration, B. Tubular reabsorption. C. Tubular secretion D. All of the above. E. Two of the above.

Answers

a. The filtering unit of the nephron is: A. Renal corpuscle.

b. Option A is correct. Urine is derived from filtering blood plasma and is formed by Glomerular filtration of the nephron(s).

The renal corpuscle is the part of the nephron responsible for the initial filtration of blood. It consists of the glomerulus and Bowman's capsule.

Urine is formed through the process of glomerular filtration, which occurs in the renal corpuscle. Subsequently, the filtrate undergoes tubular reabsorption and tubular secretion in the renal tubules, which further modify the composition of urine.

Glomerular filtration involves the filtration of blood plasma through the glomerular filtration barrier, composed of the endothelial cells, basement membrane, and podocytes, into the Bowman's capsule.

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Complete question

a. The filtering unit of the nephron is:

A renal corpuscle

B. renal tubules

C. Nephron

D. Bowman's capsule.

E. endothelial-capsular membrane.

b. Urine is derived from filtering blood plasma, and is formed by which of the following functions of the nephron(s)?

A. Glomerular filtration

B. Tubular reabsorption.

C. Tubular secretion

D. All of the above.

E. Two of the above.

Describe the normal digestion of lactose (including its subunits), and what is different about the digestive system of lactose intolerant individuals. Include how this difference results in the symptoms associated with lactose intolerance.

Answers

Lactose digestion:

Lactose is a disaccharide that is made up of two monosaccharides: glucose and galactose. Lactose is broken down into its constituent monosaccharides by the enzyme lactase, which is located in the small intestine's brush border.

Lactose intolerant individuals:

Individuals who are lactose intolerant do not produce enough lactase, the enzyme required to break down lactose into its constituent monosaccharides. This can result in lactose being partially digested and fermented by bacteria in the large intestine, resulting in gas and bloating as well as other digestive symptoms.

Signs and symptoms:

Symptoms of lactose intolerance usually appear 30 minutes to 2 hours after consuming lactose-containing foods and can include:

- Abdominal pain and cramping

- Bloating

- Gas

- Diarrhea

- Nausea

- Vomiting

In conclusion, lactose intolerance occurs when the body is unable to digest lactose properly because it does not produce enough lactase enzyme. This results in lactose being partially digested and fermented by bacteria in the large intestine, leading to symptoms such as abdominal pain, bloating, gas, and diarrhea.

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Arrange the events in the formation, storage, and release of thyroid hormone in order.
- Iodide ions are oxidized and pass through the membrane into the lumen of the follicle.
- Synthesis and packaging of TGB into secretory vesicles.
- Two diiodotyrosine molecules join to form thyroxine.
- Thyroid follicular cells trap iodide ions by actively transporting them from the blood into the cytosol.
- Iodine atoms react with tyrosines.
- Triiodothyronine and thyroxine diffuse into interstitial fluid.
- Digestive enzymes breakdown thyroglobulin.

Answers

The events in order are as follows:

1. Thyroid follicular cells trap iodide ions by actively transporting them from the blood into the cytosol.

2. Iodide ions are oxidized and pass through the membrane into the lumen of the follicle.

3. Iodine atoms react with tyrosines to form monoiodotyrosine and diiodotyrosine.

4. Two diiodotyrosine molecules join to form thyroxine and triiodothyronine.

5. Synthesis and packaging of thyroglobulin into secretory vesicles.

6. Digestive enzymes breakdown thyroglobulin.

7. Triiodothyronine and thyroxine diffuse into interstitial fluid for release.

The formation, storage, and release of thyroid hormone involve a series of intricate steps. It begins with the active transport of iodide ions from the blood into the cytosol of thyroid follicular cells.

This process allows the cells to trap iodide ions, which are essential for thyroid hormone synthesis. Once inside the follicular cells, the iodide ions are oxidized and transported across the membrane into the lumen of the follicle.

In the lumen, the iodine atoms react with tyrosines, which are amino acid residues present in a protein called thyroglobulin. This reaction leads to the formation of monoiodotyrosine and diiodotyrosine. These iodinated tyrosine molecules serve as building blocks for the thyroid hormones.

Next, two diiodotyrosine molecules join together to form thyroxine (T4) and triiodothyronine (T3), the main thyroid hormones. These hormones are synthesized and stored within the thyroglobulin molecule, which is then packaged into secretory vesicles.

At a later stage, when the body requires thyroid hormone, the secretory vesicles release thyroglobulin into the follicular lumen. Digestive enzymes present in the lumen break down thyroglobulin, releasing T4 and T3 into the interstitial fluid.

The final step involves the diffusion of T4 and T3 from the interstitial fluid into the bloodstream, where they can exert their effects on target tissues throughout the body.

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7. What is the source of maltose? a. Small intestine brush border (microvilli) b. Pancreas C. Gallbladder d. Liver e. Salivary glands

Answers

The source of maltose is  Small intestine brush border (microvilli). The correct option is a.

Maltose is a disaccharide composed of two glucose molecules linked together. It is commonly found in foods such as grains and starchy vegetables. The digestion of starch, a complex carbohydrate, begins in the mouth with the action of salivary amylase secreted by the salivary glands. However, the salivary amylase only partially breaks down starch into smaller polysaccharides.

The complete breakdown of starch into maltose occurs primarily in the small intestine. When partially digested starch reaches the small intestine, pancreatic amylase, secreted by the pancreas, continues the breakdown process, converting the remaining starch into maltose and other disaccharides.

Therefore, the small intestine brush border (microvilli) is the source of maltose digestion and conversion into glucose for absorption. So, the correct option is a.

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A person with the genetic disorder Klinefelter's syndrome has an extra X chromosome. Affected individuals have the genotype XXY. What can you infer is most likely the genetic mutation that results in Klinefelter's syndrome? (4 points)

Complete duplication of chromosomes during polyploidy

Non-disjunction during meiosis

Translocation during genetic replication

Crossing over during meiosis

Answers

The most likely genetic mutation that results in Klinefelter's syndrome is non-disjunction during meiosis.

Non-disjunction occurs when chromosomes fail to separate properly during meiosis, the process of cell division that produces eggs or sperm. In the case of Klinefelter's syndrome, non-disjunction leads to the production of sperm cells with an extra X chromosome, resulting in the XXY genotype. When a sperm with an extra X chromosome fertilizes an egg, the resulting individual will have Klinefelter's syndrome.

During meiosis, homologous chromosomes normally pair up and separate, with each resulting cell receiving one copy of each chromosome. However, non-disjunction disrupts this process, causing the failure of chromosomes to separate correctly. As a result, one cell may receive an extra chromosome, leading to the presence of an additional X chromosome in the genotype.

Other genetic mutations mentioned, such as complete duplication of chromosomes during polyploidy, translocation during genetic replication, and crossing over during meiosis, do not directly result in the XXY genotype characteristic of Klinefelter's syndrome.

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In a paragraph (7+ complete sentences) please explain the
respiratory cycle. Be sure to include descriptions of the movements
of the anatomical structures associated with this cycle as
well.

Answers

The respiratory cycle is a complex process that involves the inhalation and exhalation of air. It begins with inhalation, where the diaphragm contracts, moving downward and expanding the thoracic cavity.

The intercostal muscles also contract, elevating the ribcage. These movements increase the volume of the thoracic cavity, causing a decrease in pressure. As a result, air rushes into the lungs through the trachea and bronchial tubes.During exhalation, the diaphragm and intercostal muscles relax. The diaphragm moves back up into its dome-shaped position, and the ribcage lowers.

Other anatomical structures involved in the respiratory cycle include the alveoli, which are small air sacs within the lungs where gas exchange occurs. Oxygen from the inhaled air diffuses into the bloodstream through the thin walls of the alveoli, while carbon dioxide, a waste product, moves from the bloodstream into the alveoli to be exhaled.

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5. 2 pt. Do animals always respond as desired to a GnRH injection? Why or why not? 6. 2 pt. What is a key hallmark of a dominant follicle compared to follicles that are not dominant? Why does this allow for the dominant follicle's continued growth while subordinate follicles fail to continue growing/undergo atresia as the follicular wave progresses?

Answers

Animals do not always respond as desired to a GnRH injection due to various factors such as individual variation, hormonal imbalance, and underlying reproductive disorders.

Animals, like humans, have complex physiological systems that regulate their reproductive processes. While GnRH (Gonadotropin-releasing hormone) injections are commonly used to induce ovulation or synchronize estrus in animals, the response to these injections can vary. There are several reasons why animals may not always respond as desired:

Individual Variation: Just like humans, animals exhibit individual variation in their response to hormonal treatments. Factors such as age, breed, health status, and genetics can influence how an animal's reproductive system reacts to GnRH injections. Some animals may be more sensitive to the hormone, while others may require higher doses to achieve the desired effect.

Hormonal Imbalance: Animals with pre-existing hormonal imbalances may not respond as expected to GnRH injections. Hormonal disorders, such as polycystic ovarian syndrome (PCOS) in cattle or mares, can disrupt the normal feedback mechanisms involved in ovulation. In such cases, additional treatments or adjustments in the hormone regimen may be necessary to achieve the desired response.

Underlying Reproductive Disorders: Animals with underlying reproductive disorders, such as ovarian cysts or uterine infections, may have compromised reproductive function. These conditions can interfere with the normal development and maturation of follicles, affecting their response to GnRH injections. In such cases, veterinary intervention and targeted treatment may be required to address the underlying disorder before the animal can respond as desired.

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What property does collagen provide, as a component of bone? Select one: a. elasticity b. hardness c. flexibility d. brittleness e. resistance to compression

Answers

The property that collagen provides as a component of bone is resistance to compression. The correct answer is (E).

Collagen is a protein that is located in various parts of our body, including our skin, bones, and tendons. It makes up around 30% of the proteins in our body. Collagen is responsible for maintaining the integrity of the skin and other body tissues, as well as providing them with structure.

Collagen makes up roughly 90% of the organic bone matrix, which is the portion of bone that is not mineralized. The matrix of bones is made up of a combination of collagen fibers and various proteins that aid in mineralization, as well as glycosaminoglycans and proteoglycans that aid in hydration and other functions.

Collagen fibers are the primary source of strength and stability in the bone, providing resistance to compression and tension. Bone mineralization, on the other hand, provides hardness to the bone matrix. In other words, collagen and mineralization work together to give bones their unique mechanical properties.

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Between which fingers should the thread be held for a square knot? a. Thumb and ring finger b. Index finger and thumb c. Index and middle finger d. Thumb and middle finger e. it does not matter which fingers are used

Answers

To tie a square knot, the thread should be held between the index finger and the thumb. The correct answer is b. Index finger and thumb.

A square knot is a type of knot used to tie two ropes of equal diameter or thickness. It is also referred to as a reef knot or Hercules knot. A square knot is formed by crossing the two ends of the rope, tying an overhand knot, and then tying another overhand knot in the opposite direction. When tied correctly, the square knot will not slip or loosen.Below are the instructions on how to tie a square knot:Hold the two ends of the rope in each hand.

Cross the right end over the left end of the rope.Bring the right end back and under the left end of the rope.Tie an overhand knot by passing the right end of the rope over the left end, then under and back through the loop formed. Bring the left end over the right end of the rope.Tie another overhand knot by passing the left end of the rope over the right end, then under and back through the loop formed.

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Study Figures 2.16 and 5.17, both of which show pairs of molecules binding to each other. What would you predict about CCR5 that would allow HIV to bind to it? How could a drug molecule interfere with this binding?

Answers

A prediction about CCR5 that would allow HIV to bind to it is the presence of a specific receptor site on CCR5 that matches the binding site on the HIV envelope glycoprotein.

The prediction is based on the known mechanism of HIV entry into host cells. HIV primarily enters immune cells by binding to specific co-receptors on the cell surface. CCR5 is a chemokine receptor expressed on the surface of certain immune cells, including macrophages and T cells. For HIV to bind to CCR5, there needs to be a complementary fit between a specific region on the HIV envelope glycoprotein, known as the V3 loop.

The viral protein gp120, located on the envelope of the HIV virus, interacts with CCR5, facilitating viral entry into the host cell. This interaction triggers a conformational change in the viral envelope glycoprotein, leading to the fusion of the viral membrane with the host cell membrane and subsequent viral entry.

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What are the 3 sources of ATP for muscle contraction?
1. The products of each ATP pathway.
2. The necessary reactants for each ATP pathway (Oxygen?
Glucose?).

Answers

ATP (adenosine triphosphate) is an essential component for muscle contraction. ATP is a high-energy molecule that provides energy for the chemical reactions that occur during muscle contraction.

ATP is synthesized in the body in three ways, and the sources of ATP for muscle contraction are:1. Phosphocreatine system2. Glycolysis3. Oxidative phosphorylationThe necessary reactants for each ATP pathway are:1. Phosphocreatine system: The reactants for the phosphocreatine system are adenosine diphosphate (ADP) and creatine phosphate (CP).

The reaction is catalyzed by creatine kinase, which results in the formation of ATP and creatine.2. Glycolysis: The reactants for glycolysis are glucose and oxygen. The process takes place in the cytoplasm and does not require oxygen. The end products of glycolysis are ATP, pyruvate, and NADH.3. Oxidative phosphorylation: The reactants for oxidative phosphorylation are oxygen and glucose. This process occurs in the mitochondria and requires oxygen. The end products of oxidative phosphorylation are ATP, carbon dioxide, and water.Thus, the three sources of ATP for muscle contraction are Phosphocreatine system, Glycolysis, and Oxidative phosphorylation.

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Glomerular filtration rate can be altered by various physical and physiological processes. Which THREE of the following accurately describe conditions that will result in a DECREASED GFR? a. Increased reabsorption in the distal convoluted tubule and collecting duct
b. Vasodilation of the afferent arteriole
c. Vasoconstriction of the afferent arteriole
d. Decreased concentration of proteins in the blood Increased concentration of proteins in the blood e. Decreased filtration coefficient

Answers

The following are three accurate descriptions that result in a decreased GFR: Vasoconstriction of the afferent arteriole: If the afferent arteriole constricts, it will reduce the amount of blood that enters the glomerulus, causing a decrease in glomerular filtration rate. Increased reabsorption in the distal convoluted tubule and collecting duct. Option a .

An increase in reabsorption in the distal convoluted tubule and collecting duct will decrease the amount of filtrate that flows to the collecting ducts. Decreased filtration coefficient: A decrease in the glomerular filtration coefficient means that the amount of filtrate formed from a given amount of plasma will decrease.

Vasodilation of the afferent arteriole is not an accurate description that results in decreased GFR. If the afferent arteriole dilates, it will increase the amount of blood that enters the glomerulus, leading to an increase in the GFR.  Increased concentration of proteins in the blood is not a correct answer either.

The increased protein level in the blood will lead to increased oncotic pressure in the blood vessels, causing less fluid to filter into the glomerular capsule and leading to a decrease in GFR. However, this is the opposite of what the question asked. Option a is correct .

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Muscle fibers, their organelles and the functions of each in muscle contraction.
1. Myofibrils
2. Sarcoplasmic reticulum (and terminal cisternae)
3. T-tubules
4. Sarcolemma
5. Neuromuscular junction (synaptic cleft, stnaptic vesicles)
6. Calcium ions
7. Sodium ions
8. ATP
9. Acetylcholine, acetylcholinesterase
10. Action potential
11. Thick filaments (What proteins make up thick filaments? What is the role of that protein in muscle contraction?)
12. Thin filaments (What proteins make up thin filaments? What are the toles of those proteins in muscle contraction?)

Answers

Muscle fibers consist of organelles that aid in the function of muscle contraction.  

1. Myofibrils: Myofibrils are long, cylindrical structures within muscle fibers composed of contractile units called sarcomeres. They contain thick and thin filaments arranged in a repeating pattern, which are responsible for muscle contraction.

2. Sarcoplasmic reticulum (and terminal cisternae): The sarcoplasmic reticulum is a specialized form of endoplasmic reticulum found in muscle cells. It plays a crucial role in regulating calcium ion levels. Terminal cisternae are expanded regions of the sarcoplasmic reticulum located near the T-tubules.

3. T-tubules: T-tubules are invaginations of the sarcolemma (muscle cell membrane) that penetrate deep into the muscle fiber. They allow for the transmission of action potentials into the interior of the muscle fiber, coordinating the contraction of sarcomeres.

4. Sarcolemma: The sarcolemma is the cell membrane of a muscle fiber. It encloses the sarcoplasm (cytoplasm of the muscle cell) and is responsible for maintaining the integrity and electrical properties of the muscle fiber.

5. Neuromuscular junction (synaptic cleft, synaptic vesicles): The neuromuscular junction is the site where a motor neuron connects with a muscle fiber. The synaptic cleft is the narrow space between the motor neuron and the muscle fiber. Synaptic vesicles within the motor neuron store and release the neurotransmitter acetylcholine.

6. Calcium ions: Calcium ions play a crucial role in muscle contraction. They are released from the sarcoplasmic reticulum into the sarcoplasm in response to an action potential. Calcium ions bind to proteins on the thin filaments, initiating the contraction process.

7. Sodium ions: Sodium ions play a role in generating action potentials. They enter the muscle cell through voltage-gated channels during depolarization, leading to the propagation of the action potential along the sarcolemma.

8. ATP: ATP (adenosine triphosphate) is the energy currency of cells. It provides the energy required for muscle contraction by fueling the cross-bridge cycling between thick and thin filaments.

9. Acetylcholine, acetylcholinesterase: Acetylcholine is a neurotransmitter released from the motor neuron at the neuromuscular junction. It binds to receptors on the muscle fiber, initiating an action potential. Acetylcholinesterase is an enzyme that breaks down acetylcholine, terminating its action.

10. Action potential: An action potential is a brief electrical signal that travels along the sarcolemma of a muscle fiber. It is generated in response to the binding of acetylcholine to receptors at the neuromuscular junction, initiating muscle contraction.

11. Thick filaments: Thick filaments are composed mainly of the protein myosin. Myosin has a globular head region that interacts with the thin filaments during muscle contraction, producing force and movement.

12. Thin filaments: Thin filaments are primarily composed of the proteins actin, troponin, and tropomyosin. Actin provides the binding sites for myosin heads, while troponin and tropomyosin regulate the interaction between myosin and actin, controlling muscle contraction.

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An str region contains six repeats of a 4-nucleotide sequence. The pcr primers that recognize the dna immediately adjacent to the str region are each 10 nucleotides long. How many base pairs long will the dna fragments produced by the pcr reaction be?.

Answers

The DNA fragments produced by the PCR reaction will be 74 base pairs long.


1. The PCR primers recognize the DNA immediately adjacent to the STR region, which means they will bind to the DNA on both sides of the repeat sequence.
2. Each primer is 10 nucleotides long, so when they bind to the DNA, they will cover a total of 20 nucleotides (10 nucleotides on each side of the STR region).
3. Since the STR region contains six repeats of a 4-nucleotide sequence, the total length of the STR region is 6 repeats * 4 nucleotides/repeat = 24 nucleotides.
4. When the PCR primers bind to the DNA adjacent to the STR region, they will cover 20 nucleotides, and the STR region itself is 24 nucleotides long.
5. Therefore, the total length of the DNA fragment produced by the PCR reaction will be 20 nucleotides (covered by the primers) + 24 nucleotides (STR region) = 44 nucleotides.
6. Each base pair is made up of two nucleotides, so the final length of the DNA fragment produced by the PCR reaction will be 44 nucleotides * 2 = 88 base pairs.

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Why do we use point 6 SP for much affection of the spleen and the stomach?
A. It is the stimulation point of the spleen
B. It is an important point of liver-kidneys-spleen energy union
C. It is the earth point
D. It is a point which stimulates digestion

Answers

It is a point that stimulates digestion. We use point 6 SP for much affection of the spleen and the stomach because it is a point that stimulates digestion. The answer is option D.

Point 6 SP is a foot acupoint located in the middle of the inside of the ankle bone (medial malleolus), just behind the leg bone (tibia). The stomach and spleen are the organs that are related to this acupoint.

Acupoints are the specific locations on the body surface where the Qi or vital energy flows and connects the channels of the body.

When the acupoints are stimulated with specific techniques, they will regulate the body's function, promote the circulation of blood and Qi, and restore the balance of Yin and Yang energies in the body. Therefore, the answer is option D.

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Provide detailed scientific data to support your argument. Propose two mechanisms to explain how patients with GLUT1 deficiency (G1D) syndrome develop disorders such as seizures, movement disorders, speech disorders, and developmental delays.

Answers

GLUT1 (Glucose Transporter Type 1) deficiency syndrome (G1D) is a rare genetic disorder caused by mutations in the SLC2A1 gene. This gene encodes a protein called GLUT1, which helps transport glucose across the blood-brain barrier and into the brain.

This process is critical for the brain's energy needs, and a shortage of glucose in the brain can lead to seizures, movement disorders, speech disorders, and developmental delays. Here are two mechanisms that explain how patients with G1D develop these symptoms:

1. Reduced glucose transport into the brain:Glucose is the primary source of energy for the brain. GLUT1 transports glucose across the blood-brain barrier, which is essential for glucose uptake by the brain. G1D syndrome results in reduced glucose transport into the brain, leading to low glucose levels in the brain (hypoglycemia). Hypoglycemia can cause seizures, movement disorders, speech disorders, and developmental delays.

2. Decreased ATP production:Glucose is metabolized by the brain to produce ATP (Adenosine Triphosphate), which is the energy currency of the body. Decreased glucose uptake in G1D syndrome results in decreased ATP production in the brain. Low ATP levels can cause seizures, movement disorders, speech disorders, and developmental delays. Therefore, the two mechanisms that explain how patients with G1D develop seizures, movement disorders, speech disorders, and developmental delays are reduced glucose transport into the brain and decreased ATP production.

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Question one correct answer The esophagus is presented on a histological specimen. What is the type of the mucous tunic relief? O Smooth O Crypts O Fields and folds Villi and crypts O Pits and fields

Answers

The type of the mucous tunic relief of the esophagus in a histological specimen is Pits and fields. Option d is correct.

What is a histological specimen?

Histology is a medical specialty that studies cells and tissues at a microscopic level. The histological examination of tissue is carried out on tissue samples. These samples may come from biopsies, surgical excisions, and autopsies. A histological specimen is a sample of tissue or a biopsy that is taken from a human or an animal and used for medical and pathological examination.

The esophagus is a muscular tube that runs from the pharynx to the stomach. The food bolus passes from the pharynx to the esophagus and is transported to the stomach by peristalsis, which is a series of coordinated muscle contractions.

The mucosa of the esophagus is lined by a stratified squamous epithelium. The mucous tunic contains a network of pits and fields that aid in lubricating the food bolus as it passes down the esophagus. The pits and fields help to trap food particles, and the lubricating mucus aids in the passage of food down the esophagus. Therefore option d is correct answer.

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Give a general overview for one cycle of the
Na+/K+ pump: what is used, what is moved, and
where.

Answers

The Na+/K+ pump is a type of active transport protein that moves Na+ and K+ ions across the cell membrane against their concentration gradients. It is used to maintain the ion balance inside and outside the cell.

For every cycle of the Na+/K+ pump, ATP (adenosine triphosphate) is used to provide energy for the pump's movement. For every cycle of the Na+/K+ pump, three Na+ ions are moved out of the cell and two K+ ions are moved into the cell. The Na+/K+ pump is moved across the cell membrane against the concentration gradient of both ions. Three Na+ ions are moved from the intracellular space to the extracellular space while two K+ ions are moved from the extracellular space to the intracellular space.

In conclusion, the Na+/K+ pump moves three sodium ions out of the cell and two potassium ions into the cell for every cycle. ATP is used to provide the energy needed for the pump to move the ions across the cell membrane against their concentration gradient.

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Question 11 2 pts Based on the baroreceptor reflex, state how the following would respond due to a decrease in blood pressure: [ Select] Stretch of Baroreceptors [ Select] Firing of Action potentials [ Select] Vasomotor Center [ Select] Cardio Acceleratory Center [ Select] Blood vessel diameter [ Select] Heart Rate [ Select] Stroke Volume
[ Select]Cardiac Output [ Select] Blood Pressure [ Select] : increase/decrease

Answers

Based on the baroreceptor reflex, stretch of baroreceptors would respond due to a decrease in blood pressure.

What is the baroreceptor reflex?

The baroreceptor reflex is a feedback loop that assists in the maintenance of blood pressure. It is a negative feedback system that operates in response to changes in blood pressure.

The baroreceptor reflex's primary goal is to maintain a steady blood pressure despite fluctuations in vascular resistance and cardiac output.

In the event of a decrease in blood pressure:

Stretch of Baroreceptors: It decreases the firing of action potentials. This is caused by reduced stretching of the carotid arteries' and aortic arches' baroreceptors, which detect changes in arterial pressure. The stimulation frequency of the afferent fibers reduces as baroreceptor activity decreases.

Vasomotor Center: It will respond by increasing sympathetic activity. When the baroreceptors detect a decrease in blood pressure, they generate less action potential activity, leading to a decrease in the frequency of inhibitory signals transmitted to the vasomotor center. This, in turn, increases sympathetic activity.

Cardio Acceleratory Center: It will be activated to increase cardiac output. A decrease in cardiac output activates the cardiac accelerator center in the medulla, which raises sympathetic activity and increases heart rate, contractility, and peripheral vascular resistance.

Blood Vessel Diameter: It decreases, as the sympathetic nervous system is activated, and vasoconstriction occurs, causing a decrease in vessel diameter.

Heart Rate: It increases due to sympathetic nervous system stimulation, leading to a rise in heart rate.

Stroke Volume: It increases because the increase in heart rate causes the heart to pump more blood.

Cardiac Output: It increases due to the increased heart rate and stroke volume.

Blood Pressure: It increases as a result of the increase in cardiac output and peripheral vascular resistance.

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Thomas rides in an elevator with a young child suffering from the common cold. Like most young children, the sick girl fails to cover her mouth when she sneezes thus releasing cold viruses (Rhinoviruses) into the air of the elevator. Thomas has the misfortune of inhaling one of those viruses. These questions follow step-wise as Thomas' immune system attempts to prevent the infection 1)Identify three physical barriers in Thomas' nasal cavity that attempt to prevent infection by the virus.

Answers

The physical barriers in Thomas' nasal cavity that attempt to prevent infection by the virus are: Nasal hair, mucous membranes, and cilia.

The human respiratory system is a complex network of organs that are responsible for breathing and the exchange of oxygen and carbon dioxide between the body and the environment. It's a protective system that has several physical and chemical barriers that protect against various airborne infections. One of the most significant physical barriers of the respiratory system is the nasal cavity. Here are the three physical barriers in Thomas' nasal cavity that attempt to prevent infection by the virus:Nasal hair Mucous membranes Cilia.

These structures act as physical barriers that help in the process of filtering, trapping, and expelling the harmful particles and pathogens from the respiratory tract. The nasal hair filters the air by trapping larger particles like pollen and dust. The mucous membranes produce mucus, which traps the airborne pathogens, viruses, and bacteria, and prevents them from entering into the lungs. Lastly, the cilia are tiny hair-like structures that move back and forth, sweeping the trapped mucus and pathogens out of the respiratory system.

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1. Classify neurons on the basis of function. Be sure to discuss each type.

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Neurons are the nerve cells that transmit information in the nervous system. There are three types of neurons based on their functions. They are Sensory neurons, Motor neurons, and Interneurons.

Sensory neurons: These neurons are responsible for conveying sensory information from sensory organs such as eyes, ears, nose, and skin to the spinal cord and brain. These neurons are also known as afferent neurons.

Motor neurons: These neurons are responsible for transmitting information from the central nervous system to the effectors, i.e., muscles and glands. These neurons are also known as efferent neurons.

Interneurons: These neurons are found in the central nervous system and are responsible for transmitting signals between sensory and motor neurons. They are located in the spinal cord and the brain. They act as a link between sensory and motor neurons.

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• Explain the difference between Excitatory and Inhibitory Synapses • Give an example of an Excitatory and Inhibitory neurotransmitter

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The main difference between excitatory and inhibitory synapses is the response they elicit in the postsynaptic neuron. An excitatory synapse increases the probability of an action potential occurring in the postsynaptic neuron, whereas an inhibitory synapse decreases it.

Excitatory neurotransmitters: These neurotransmitters activate or excite the neurons by increasing the chances of an action potential being generated. Glutamate is an example of an excitatory neurotransmitter.Inhibitory neurotransmitters: These neurotransmitters inhibit or decrease the chances of an action potential being generated. GABA (Gamma-Aminobutyric Acid) is an example of an inhibitory neurotransmitter.Example:If a neuron is under the influence of an excitatory neurotransmitter, like glutamate, more positively charged sodium ions will flow into the neuron than negatively charged potassium ions flow out. If enough sodium ions enter the cell to depolarize it past a certain threshold, an action potential will be generated and the message will be transmitted to the next neuron in the chain.

If a neuron is under the influence of an inhibitory neurotransmitter, like GABA, more negatively charged chloride ions will flow into the cell than positively charged sodium ions will flow out, hyperpolarizing the cell and making it more difficult to generate an action potential. So, The main difference between excitatory and inhibitory synapses is the response they elicit in the postsynaptic neuron.

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URGENT PLEASEE
During lipid metabolism, which of the following become a ketone body? excess acetyl groups excess hydroxyl groups Oglucose Oglycerol

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Excess acetyl groups become ketone bodies during lipid metabolism, serving as an alternative fuel source for tissues during fasting or low carbohydrate intake.

During lipid metabolism, excess acetyl groups can be converted into ketone bodies through a process called ketogenesis. Ketone bodies, such as acetoacetate, beta-hydroxybutyrate, and acetone, are produced in the liver when there is an excessive breakdown of fatty acids and a limited availability of glucose.

Acetyl groups are derived from the breakdown of fatty acids through beta-oxidation. When carbohydrate stores are depleted, such as during fasting or a low-carbohydrate diet, the body shifts to metabolizing fatty acids for energy. As fatty acids are broken down, acetyl-CoA is generated. Excess acetyl-CoA can enter the ketogenesis pathway in the liver, leading to the production of ketone bodies.

Ketone bodies serve as an alternative fuel source for tissues, especially the brain, during periods of prolonged fasting or low carbohydrate intake. They can be converted back to acetyl-CoA in various tissues and used in the citric acid cycle for energy production.

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Nick follows a low protein/low calcium diet as his grandma insists this diet is the key to a long life. He plans on living this lifestyle for the rest of his life.Considering his current lifestyle, what modifications could Nick make for the rest of his life to ensure he ages successfully?

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Nick follows a low protein/low calcium diet as his grandma insists this diet is the key to a long life. Modifications Nick could make for the rest of his life to ensure he ages successfully are as follows: Nick could incorporate some foods that are high in protein but low in calcium in his diet, to ensure that his body is receiving the required amount of protein for growth and repair of tissues.

It is essential that the protein that Nick consumes is of high quality; therefore, he could include lean meats, eggs, poultry, beans, peas, soy products, and unsalted nuts in his diet. These foods are excellent sources of high-quality protein. Nick could also consider taking calcium supplements, as calcium is crucial for healthy bones and teeth. Calcium supplements should be taken under the guidance of a doctor to ensure that the appropriate amount is taken. It is vital to eat a balanced and nutritious diet to ensure a healthy and long life, and Nick should consider making some modifications to his diet to improve his overall health.

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Explain the humoral control of the circulation.

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The humoral control of circulation refers to the regulation of blood flow and blood pressure by various chemical substances, known as humoral factors, that are present in the blood. These factors include hormones, enzymes, and other molecules that act as messengers to communicate with different organs and tissues involved in controlling the circulation.

One of the key humoral factors involved in circulatory control is the hormone called angiotensin II. It is produced by the activation of the renin-angiotensin system in response to low blood pressure or decreased blood flow to the kidneys. Angiotensin II acts on blood vessels to cause vasoconstriction, narrowing the vessels and increasing blood pressure. It also stimulates the release of aldosterone, a hormone that promotes salt and water retention by the kidneys, further increasing blood volume and pressure.

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Interpret the results of the blood typing test. This person has_____blood No agglutination agglutination Anti-A Anti-B Anti-Rh Choose all that apply: Which receptors are found on helper T cells? O CD8 receptors O CD4 receptors O a piece of viral protein O T-cell receptors O an antigen from the microbe A virus is injected into a rabbit and the rabbit is allowed to make antibodies against the viral antigen. These antibodies are then removed from the rabbit plasma and injected into a human to combat an infection by the same virus. This would be an example of O innate immunity O artificially induced passive immunity O artificially induced active immunity O naturally acquired passive immunity, O naturally acquired active immunity Choose all that apply: Which of the following statements are true? O the primary response occurs during the first exposure to a pathogen O the secondary response is usually much more rapid than the primary response O during the primary response, IgG antibodies are most commonly formed O during the secondary response, IgG antibodies are more commonly formed O the primary response to a pathogen usually creates enough antibodies to destroy it Calculate Heart Rate. HR = b/min. Only count complete boxes. Do not count 1/2 boxes. You will need to round your answer. Do not include decimal points.

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CD4 receptors are found on helper T cells. CD8 receptors are found on cytotoxic T cells.

This would be an example of:

Artificially induced passive immunity. This is because the antibodies obtained from the rabbit plasma are directly injected into the human to combat the infection, providing immediate protection without the human's immune system actively producing the antibodies.

The secondary response is usually much more rapid than the primary response.

During the primary response, IgG antibodies are not commonly formed. IgM antibodies are typically the first antibodies produced.

During the secondary response, IgG antibodies are more commonly formed.

The blood typing test results indicate that this person has no agglutination, which suggests that they have type O blood and do not have the A or B antigens present on their red blood cells. Additionally, there is no agglutination of the Rh factor, indicating that the person is Rh-negative.

The receptors found on helper T cells are CD4 receptors. These receptors play a crucial role in the immune response by recognizing antigens presented by antigen-presenting cells and activating the immune system.

The scenario described, where antibodies generated in a rabbit against a viral antigen are transferred to a human to combat an infection by the same virus, represents artificially induced passive immunity. The pre-formed antibodies provide immediate protection to the human, but the immune response is temporary since the transferred antibodies will eventually degrade.

The following statements are true:

The primary response occurs during the first exposure to a pathogen.

The secondary response is usually much more rapid and stronger than the primary response.

During the primary response, IgM antibodies are commonly formed.

During the secondary response, IgG antibodies are more commonly formed. The secondary response is characterized by the production of memory B cells, which can quickly differentiate into plasma cells and produce large amounts of IgG antibodies upon re-exposure to the same pathogen.

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Do
muscles have different shapes? If so what are they and how do they
differ in function and use? And can they change shape and lever
arms when moved through other joints(how)?

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Yes, muscles can have different shapes, including parallel, convergent, pennate, and circular. Each shape has unique structural and functional characteristics.

Parallel muscles have fibers that run parallel to the long axis of the muscle, providing a greater range of motion but less force production. Convergent muscles have fibers that converge toward a common attachment point, allowing for strength and versatility. Pennate muscles have fibers that attach obliquely to a central tendon, maximizing force production but reducing range of motion. Circular muscles form rings around body openings and function in constriction or dilation.

Muscles can change shape and lever arms when moved through other joints. This is achieved through the interaction of muscles, tendons, and bones. When a muscle contracts, it pulls on its attachment points, causing movement around a joint. The lever arm, or moment arm, of a muscle changes depending on the position and angle of the joint, affecting the mechanical advantage and force production. Muscles adapt to changes in joint angles by adjusting their fiber length and orientation, allowing for optimal leverage and force generation during movement.

In conclusion, muscles can have different shapes, which impact their function and use. They can change shape and lever arms to accommodate movement through various joints, enabling efficient force generation and motion.

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1) 13- Regarding active transport, which of the following is not TRUE: a Primary active transport is a movement of substances against concentration electric" gradient. b- Co-transport is the movement of two substances in one direction. c. In Secondary active transport the two substances are moved actively. d- In Secondary active transport one substance is moved actively & the other substance is moved passively.

Answers

Active transport is a biological process in which solutes are moved across a cell membrane, against a concentration gradient, by a molecular pump.

This process requires energy in the form of ATP, which is used by the pump to move molecules from low concentration to high concentration. Regarding active transport, the following statements are true except:In Secondary active transport the two substances are moved actively. The correct statement is "In Secondary active transport one substance is moved actively and the other substance is moved passively.

In secondary active transport, one substance moves against its concentration gradient, which is powered by the concentration gradient of another substance that moves with its concentration gradient. In co-transport, both solutes move in the same direction across the membrane. On the other hand, in primary active transport, ATP is used directly to move a solute against its concentration gradient.

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Question 21 Match the digestive term to the definition or description Enzyme for starch digestion 1. Nuclease Enzyme for fat digestion 2. Protease Enzyme for protein digestion 3. VLDL’s
Enzyme for nucleic acid digestion 4. Amylase Emulsifies fat for absorption 5. LDL’s
Carry triglycerides from the intestines to the liver 6. Bite
Carry triglycerides from the liver to the tissues 7. Lipase
Carry cholesterol from the liver to the tissues 8. Chylomicrons
Carry cholesterol from the tissues to the liver 9. HDL's

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The correct digestive term for the definition are 4. Amylase, 7. Lipase, 2. Protease, 1. Nuclease, 6. Bile, 8. Chylomicrons, 3. VLDL's, 5. LDL's, and 9. HDL's

Enzyme for starch digestion (1. Nuclease): Nuclease is actually an enzyme responsible for nucleic acid digestion, not starch digestion. The correct answer for enzyme for starch digestion is 4. Amylase. Amylase is produced by salivary glands and the pancreas and breaks down starch into smaller sugar molecules like maltose.

Enzyme for fat digestion (7. Lipase): Lipase is an enzyme that breaks down fats into fatty acids and glycerol. It is produced by the pancreas and helps in the digestion and absorption of dietary fats.

Enzyme for protein digestion (2. Protease): Protease is an enzyme responsible for protein digestion. It breaks down proteins into smaller peptides and amino acids, facilitating their absorption and utilization by the body.

Enzyme for nucleic acid digestion (1. Nuclease): Nuclease is an enzyme that breaks down nucleic acids (DNA and RNA) into nucleotides. It helps in the digestion and absorption of dietary nucleic acids.

Emulsifies fat for absorption (6. Bile): Bile is not an enzyme but a fluid produced by the liver and stored in the gallbladder. Bile emulsifies fats, meaning it breaks them down into smaller droplets, increasing their surface area and facilitating their digestion and absorption.

Carry triglycerides from the intestines to the liver (8. Chylomicrons): Chylomicrons are lipoprotein particles that transport dietary triglycerides from the intestines to various tissues in the body, including the liver.

Carry triglycerides from the liver to the tissues (3. VLDL's): Very low-density lipoproteins (VLDLs) transport triglycerides synthesized in the liver to different tissues in the body for energy storage.

Carry cholesterol from the liver to the tissues (5. LDL's): Low-density lipoproteins (LDLs) transport cholesterol synthesized in the liver to various tissues in the body. LDLs are often referred to as "bad cholesterol" as high levels of LDLs are associated with an increased risk of cardiovascular diseases.

Carry cholesterol from the tissues to the liver (9. HDL's): High-density lipoproteins (HDLs) collect cholesterol from various tissues and transport it back to the liver for elimination from the body. HDLs are often referred to as "good cholesterol" as they help remove excess cholesterol from the bloodstream and protect against cardiovascular diseases.

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