What is the purpose of spindle fibers during mitosis?

What Is The Purpose Of Spindle Fibers During Mitosis?

Answers

Answer 1

Answer: Separate the Sister Chromatids

Explanation: Spindle Fibers are on either end of the cell pulling the chromosomes apart during Anaphase


Related Questions

Identify three selection pressures rhat Darwin would have had to rule out before determining that competition for limited food resources drive natural selection on the Galapagos Island.

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Answer:

Darwin nunez or Charles Darwin

urjnun'uemb anyone intrested to come for 21 questions?​

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Answer:

what is that? for biology?

endoscopy equipment becomes highly contaminated with human tissues and fluids, and should be sterilized in a low-temperature cabinet using which sterilants?

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Hydrogen peroxide and Peracetic alcohol.

Sterilized in a low-temperature cabinet using which sterilants.

An endoscopy process includes inserting a thin, bendy tube referred to as an endoscope down your throat and into your esophagus. A tiny digital camera on the give up of the endoscope we could your provider examine your esophagus, belly and the beginning of your small gut, also known as the duodenum.

An endoscopy is used to diagnose situations that affect the digestive machine. Endoscopy can assist perceive ulcers, bleeding, celiac ailment, blockages, infection, and tumors. It can help locate the cause of unexplained symptoms, including heartburn, abdonimal pain, bleeding, nausea, vomiting, and pain.

After you have an endoscopy, you will live on the health center or sanatorium for 1 to two hours.

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which change would not affect the relative rate of action of enzyme x

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Answer:

b

Explanation:

staphylococcus species are resident human microflora. if you wanted to culture staphylococcus where should you swab?

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In order to  culture staphylococcus, we used to swab  in the throat, nose,  and skin.

Staph infections are caused by staphylococcus microscopic organisms. These sorts of germs are commonly found on the skin or within the nose of numerous healthy individuals. Most of the time, these microscopic organisms cause no issues or cause moderately minor skin infections. But staph diseases can turn dangerous on the off chance that the microscopic organisms attack more profoundly into your body, entering your circulatory system, joints, bones, lungs, or heart. A developing number of something else sound individuals are creating life-threatening staph infections. Treatment ordinarily includes antimicrobial and cleaning of the infected zone

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Relate How can the increased
demand on water affect water
quality

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As more Organisms need water, The only clean source of water becomes scarce and finished, leaving only few clean pure sources of water, but much impure sources of water

The two muscles that insert on the fifth phalanx or on the fifth metatarsal are the __________.

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The two muscles that insert on the fifth phalanx or on the fifth metatarsal are the extensor digitorum longus and fibularis tertius.

Where is extensor digitorum longus located ?Extensor digitorum longus is located lateral to m. tibialis anterior in its proximal part and extensor hallucis longus distally. Its origin is on the tibia and interosseous membrane, inserts into the medial and distal phalanxes II-V digitorum, is innervated by fibular profundus. Which functions for dorsiflexion and abduction.The innervation of the ankle comes from the lumbar plexus and the sacral plexus. The muscle innervation that controls the movement of the ankle comes from the tibial nerve, deep fibular nerve and superficial fibular nerve. While the sensory nerves come from the sural nerve and saphenus.

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1. with regard to linked genes on the same chromosome, which of the following statements is false? a. crossing over is needed to produce nonrecombinant offspring. b. crossing over is needed to produce recombinant offspring. c. crossing over is more likely to separate alleles if they are far apart on the same chromosome. d. crossing over that separates linked alleles occurs during prophase of meiosis i.

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With regard to linked genes on the same chromosome, the following statements is false a.) crossing over is needed to produce the nonrecombinant offspring.

What are linked genes?

When genes are present on different chromosomes or far apart on the same chromosome, they assort independently and can be said to be unlinked.

Genes are said to be linked when they are closely together on the same chromosome. Sex-linked genes are located on sex chromosome and X-linked genes are located on X chromosome. The crossing over frequency  between genes can be used to construct linkage maps that show the locations of genes on chromosomes.

Genetic linkage analysis helps in determining whether the disease phenotype is caused by mutation in a single gene.

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how do reptiles and amphibians differ from fish? answer reptiles and amphibians are ectotherms while fish are not. reptiles and amphibians have limbs present while fish do not. reptiles and amphibians have an amnion and fish do not. reptiles and amphibians have jaws while fish do not.

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Fish lack limbs, although amphibians and reptiles do.

While amphibians are born with gills for breathing underwater, reptiles are born with lungs. where they spend their early growth after hatching. Amphibians have thin, smooth skin, whereas reptiles have scales. Reptiles include lizards, turtles, and snakes.

A reptile lives on both land and water, unlike a fish, which only exists in water. A fish is a type of cold-blooded or ectothermic aquatic vertebrate. The reptile, which has scales or scutes covering it, is a cold-blooded creature as well. Scales are a feature of fish, though cartilaginous fish lack them.

Cold-blooded vertebrates include fish, reptiles, and amphibians. Animals with a backbone and an internal skeleton are known as vertebrates.

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which disorder results in decreased erythrocytes and platelets with changes in leukocytes and has clinical manifestations of pallor, fatigue, petechiae, purpura, bleeding, and fever?

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Pallor, purpura, petechiae, increased risk of mucosal bleeding, increased risk of infection, and weariness due to pancytopenia are all signs of aplastic anaemia.

When the body ceases making enough new blood cells, aplastic anaemia develops. You get worn out and more vulnerable to infections and uncontrolled bleeding as a result of the disease. Aplastic anaemia is an uncommon and dangerous illness that can appear at any age.

The bone marrow, the sponge-like substance inside our bones, is where the stem cells in aplastic anaemia are damaged. The bone marrow's stem cells can be harmed by a variety of illnesses and ailments. As a result, less red blood cells, white blood cells, and platelets are produced by the bone marrow.

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which choice among a-e below is false? a. transferrins: an iron-binding protein in your body b. fever: increases t cell activity and lowers iron availability c. amps: peptides of the innate immune system that possess antimicrobial activity d. interferon: acts on increfhypothalamus to elevate body temperature set point causing fever e. alternative complement pathway: complement activated by binding to pathogen surface glycolipids f. none are false; a - e are all true

Answers

The false statement in the given question is: (d) interferon: acts on increfhypothalamus to elevate body temperature set point causing fever.

Fever is the state of elevated temperature of the body. The normal body temperature is 98.6° F (37° C). Any increase above this temperature is febrile. Molecules called pyrogens released from the body of pathogens trigger the hypothalamus to elevate the body temperatures.

Interferon is the immune protein released from the cells that get infected by the virus. The function of the interferon is to inhibit the viral replication inside the body so as to prevent the spread of infection inside the body.

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which antibody isotype to antigen can inhibit naive b lymphocyte activation of pre existing (already present)?

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IgG antibody isotype to antigen can inhibit naive b lymphocyte activation of pre existing (already present).

What is Antibody ?

Proteins called antibodies defend you when your body comes into contact with an unwelcome chemical. Antibodies, which are made by your plasma, bind to these foreign substances and drive them out of your body.

Immunoglobulin is another name for an antibody.

Antigens have molecules on their surfaces that are different from those your body naturally produces. Therefore, as soon as an antigen enters your body, your immune system immediately recognises it. Your immune system requests antibody defence in order to combat this antigen invader.

The B cell produces antibodies (specialized white blood cells). A B cell multiplies and clones when it comes into touch with an antigen. These plasma cells, also known as cloned B cells, unleash countless amounts of antibodies into your lymphatic and blood systems.

Your body has antibodies in a number of places, including your skin, lungs, tears, saliva, and even breast milk. In actuality, colostrum contains significant amounts of antibodies. Because of this, breast- or chest-feeding can strengthen your baby's immune system.

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The graph shows the progress of a chemical reaction with and without the presence of an enzyme. Analyze the data. Which statement accurately reflects what is shown in the graph? A. The presence of the enzyme decreases the activation energy. B. The presence of the enzyme decreases the change in free energy. C. The presence of the enzyme decreases the energy of the products. D. The presence of the enzyme prevents the reaction from progressing

Answers

The difference between reactions mediated or not by enzymes, is the speed at which they occur, and hence, the required activation energy. A) The presence of the enzyme decreases the activation energy.

What are enzymes?  

Enzymes are proteins with intracellular catalytic properties that accelerate different natural chemical reactions. These reactions occur naturally, but they are accelerated in the presence of the enzyme.

Enzymes are in charge of catalyzing cell metabolism. Since they are proteins, they need an accurate tridimensional structure to accomplish their function. There is a limited temperature and pH level at which they lose that structure and denaturalize.

Concerning the reaction, in the enzyme's presence and absence, the substrate and the product are the same.

The main difference is the activation energy required to carry out the reaction.

Let us remember that activation energy is the one required to create or break bonds between molecules. Usually, the higher the activation energy is, the slower the reaction occurs.

In the presence of the enzyme, the reaction needs a lower activation energy than in its absence.

Without the enzyme ⇒ higher activation energy ⇒ slower reaction With the enzyme ⇒ lower activation enegy ⇒ faster reaction

According to this framework, the correct option is A. The presence of the enzyme decreases the activation energy.

Note: Since I could not find the complete question, I will attach a graph showing the progress of a chemical reaction with and without the presence of an enzyme. This diagram should be the same as yours.

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which characteristic makes hemoglobin's structure such a good match for its function as an oxygen carrier

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The characteristic makes hemoglobin's structure such a good match for its function as an oxygen carrier is that each hemoglobin molecule can bind four oxygen molecules.

What is hemoglobin?

The iron-containing oxygen-transporting metalloprotein known as hemoglobin, often known by the abbreviations Hb or Hgb, is found in the red blood cells of almost all vertebrates as well as some invertebrate organs. The oxygen from the respiratory organs is transported to the rest of the body by hemoglobin in the blood.

What is the characteristic of hemoglobin?

Hemoglobin is a two-way respiratory carrier that facilitates the movement of carbon dioxide back and forth from the lungs to the tissues. Hemoglobin's affinity for oxygen in arterial circulation is high, but its affinities for carbon dioxide, organic phosphates, hydrogen, and chloride ions are low.

Thus from above conclusion we can say that the characteristic makes hemoglobin's structure such a good match for its function as an oxygen carrier is that each hemoglobin molecule can bind four oxygen molecules.

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On which day is the level of LH in the bloodstream at its highest? What event occurs immediately after this peak?

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Answer:

LH reaches its highest concentration on day 13. This causes the follicle to burst, releasing the ovum, and the follicle begins to develop into a corpus luteum.

The level of LH in the bloodstream at its highest at the 14th day of the menstrual cycle. Ovulation takes place ta the 14th day of the month which does ovulation.

What is the full form of LH ?

The full form of LH is leutinizing hormone.

Corpus luteum is formed at the 14th day of the cycle that is the matured graffian follicle when releases an ovum then the matured graffian follicle makes the structure called as the corpus luteum which is yellowish in color.

With the increase in LH, other hormones also peak up because the hormones have to be associated with the thickening of the uterus walls and the walls of uterus have to be thickened up so as to make the uterus fit for baby production.

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What is a limitation of the model in representing the steps of transcription and translation?

Answers

It does not show that the ribosome stops translating when it encounters a stop codon.

Hope this helps:)

in the human life cycle a.meiosis produces haploid gametes, and fertilization creates a diploid cell that divides by mitosis to produce a new individual. b.mitosis produces haploid gametes, and fertilization creates a diploid cell that divides by meiosis to produce a new individual. c.diploid gametes reproduce by meiosis to produce haploid daughter cells that divide by mitosis to produce a new individual. d.diploid gametes reproduce by mitosis to produce diploid daughter cells that divide by meiosis to produce a new individual

Answers

Meiosis produces haploid gametes, and fertilization creates a diploid cell that divides by mitosis to produce a new individual.
Understanding meiosis
One method of cell division is meiosis.  Reporting from the official website of the Ministry of Education and Culture of the Republic of Indonesia, meiotic division only occurs in the sex organs.
The function of Meiosis is to produce gametes (egg cells and sperm cells).  This division produces daughter cells that have half the chromosomes of the parent cell.
The number of chromosomes possessed by daughter cells is n or is called haploid.  Hence, meiotic cell division is referred to as reduction division.
Meiosis is a cell division thatthat produces 4 daughter cells, each of which has half the number of chromosomes of the parent cell.
And while body cells carry a total of 46 chromosomes, gamete cells only carry 23 chromosomes.  A healthy young adult male will produce several hundred million gametes each day.  In women, sex cells or ovum development follows a long process, starting in the fifth month after the woman is conceived.  Meiosis begins at this stage, but stops at the egg precursor cell stage – or primary oocyte – during fetal development.


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biochemical oxygen demand (bod) is controlled by the concentration of choose one: a. heterotrophic microorganisms. b. multicellular organisms. c. autotrophic microorganisms. d. benthic microorganisms.

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The quantity of multicellular organisms in an area determines the biochemical oxygen demand (bod).

Where do microorganisms live?

Microbes are extremely little living entities that can't be seen with the human eye and are present all around us. In the air, on land, and in water, they exist. Millions of these germs, also known as microorganisms, reside inside the human body. While certain microorganisms make us ill, others are beneficial to our health.

Which of the following factors is the primary driver of an increase in the biochemical oxygen demand in aquatic environments?

In order to respire and catabolize organic molecules, microbial heterotrophs need oxygen. These actions reduces the oxygen content of the aqueous body, raising its BOD.

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Proteins that will go to different locations will likely have different _______ sequences.

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Answer:

Messenger im sure

HELPPP!!! Question 6 of 10 Which two statements describe examples of inferences used to draw scientific conclusions?
A. A cheetah has a speed of 33 m per second over short distances because the cheetah sprinted 330 m in 10 seconds.
B. T. rex must have been a carnivore because fossilized remains show teeth well-suited to biting and crushing bones.
C. It will rain this afternoon because the satellite images show increased cloud cover moving in this direction.
D. The population of black bears in a 100 km² area has increased from 14 to 18 in the past year.​

Answers

Answer:

Determine which equation is false, based on the solution set S:{4}.

3t = 12

3m + 7 = 14

4(4c + 1) = 68

9 = 5p − 11

Explanation:

Answer:B and C

Explanation: inference is a guess based on reasoning, not numbers, using educated guesses is an inference. Finding out things with numbers isnt. So B and C are the answers

true or false? generally, the more food in the stomach, the faster the absorption rate of alcohol

Answers

Generally, the more food in the stomach, the faster the absorption rate of alcohol the statement is false.

A serving of alcohol needs between 30 and 2 hours after intake to completely enter the bloodstream. Alcohol is metabolized by the body at a rate of 0.25 ounces per hour. It is significant to remember that gender might affect how quickly alcohol is absorbed.

A person's ability to absorb alcohol can vary depending on their gender; for instance, a 140-pound male can consume two drinks in an hour and have a blood alcohol level of 0.038, whereas a 140-pound female can consume two drinks in an hour and have a blood alcohol level of 0.048. Women's BACs are greater than men's after consuming the same quantity of alcohol because they have less dehydrogenase, an enzyme that breaks down alcohol in the stomach.

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B cells have antigen receptors that bind to antigens that are either freely dissolved or present on the surface of invading/foreign cells. T cells have antigen receptors that.

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T cells have antigen receptors that c. bind to antigen fragments presented on major histocompatibility complexes by host cells.

The major histocompatibility complex forms a set of cell surface proteins that are essential in providing immunity to the cells.

Unlike the B cells that can directly make antibodies against the antigens, the T cells are involved in such a immune response in which the foreign particles have to be presented to them in order for them to attack them.

These foreign particles are presented to the T cells through the cell surface proteins that make the major histocompatibility complex. The T cells are important for providing adaptive immunity to the body of a person.

Although a part of your question is missing, you might be referring to this question:

B cells have antigen receptors that bind to antigens that are either freely dissolved or present on the surface of invading/foreign cells. T cells have antigen receptors that

a. are active only in lymph nodes

b. bind to antigens that are either freely dissolved or present on the surface of invading/foreign cells

c. bind to antigen fragments presented on major histocompatibility complexes by host cells

d. bind only to freely dissolved antigens in the plasma

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The birth of the study of human relations within business organizations can be traced to?.

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The Hawthorne studies can be traced to the birth of the study of human relations within business organizations.

The Hawthorne investigations, which Elton Mayo and Fritz Roethlisberger carried out between 1924 and 1932, gave rise to the human relations movement. The Hawthorne Effect is when participants in an experiment try to alter or enhance their behavior only because it is being assessed or researched. In the late 1920s and early 1930s, Western Electric's facility in the Chicago suburb of Hawthorne conducted tests that led to the invention of the phrase.

Hawthorne studies were created to look at ways to boost employee productivity. According to the Hawthorne theory of management, employee productivity is also dependent on management's concern for their well-being and the pay they are paid.

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Which functional region of the cerebellum is implicated in planning the sequence and timing of complex movements?.

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The part of the brain involved in the sequence and timing of complex movements is the cerebrocerebellum.

 The cerebellum is the largest part of the brain that initiates and coordinates movement and regulates temperature.

The brain is divided  into 3  functional areas which are;

cerebrocerebellum spinocerebellum vestibulocerebellum

cerebrocerebellum communicates with the cerebral cortex and is thought to be involved with planning and initiating movement it receives inputs from the cerebral cortex and pontine nuclei and sends inputs sends the outputs to the thalamus and red nucleus

spinocerebellum this part of the cerebellum is involved in regulating body movements by allowing for error correction

vestibulocerebellum gives signals which detect the head movement and send signals through the cerebellum to the head rotation and maintain a stable center of gaze.

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how far each of the following statements is correct with explanation:

Spores of fern plant are produced due to mitosis

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The sporangia, which resemble sacs, in ferns undergo meiosis to generate one type of spore (homosporous), in contrast to several other non-flowering vascular plants. The diploid spores (also known as spore mother cells or sporocysts) go through meiosis within each sporangium.Spores are typically formed by meiosis in the sporophyte and are haploid and unicellular in nature. A new sporophyte is produced when two gametes combine. This cycle is referred to as a generational alternation. Many fungi use the haploid Mito spores produced during mitosis for asexual reproduction.The life cycle of ferns On the underside of the leaves of mature plants, spores are produced. These produce tiny prothalli, or plants with the shape of a heart, once they germinate. These plants produce both male and female cells and following fertilization the adult fern starts to grow.Bacteria, fungi, algae, and plants all create spores. As a major resting or dormant stage in the bacterial life cycle, bacterial spores assist the organism survive times of unfavorable environment.

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Are Africanized honey bees a direct or indirect threat? Why?

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Alien bee genus aid in pollination, but the Africanized honey bee is a danger to human health.

What are Africanized honey bees?

The African honey bee is of native to most of the central and southern parts of Africa. Its sting is no more menacing than other bees, but it is unusual. It is much more aggressive as compared to other bees, with a propensity to pursue and send many attackers after any perceived threat. Africanized honey Bees are killer bees that are very dangerous because they attack intruders in much greater as compared than European Honey Bees. In Brazil, they have killed some 1,000 humans with victims receiving ten times as compared to the European bees.

So we can conclude that Honeybees help provides us with most of the food we eat, either straightly by pollinating food crops or indirectly by pollinating food sources consumed by domestic.

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if a mutation occurs on a segment of dna that codes for an enzyme, what is most likely to happen to the enzyme?

Answers

Answer:

it'll denature or reshape the enzyme

(remember enzymes are shaped specifically)

is human evolution over? if not, what directions might human evolution take in the future? what do you imagine will be the main selective forces future humans face? describe some potential cultural adaptations and some potential genetic adaptations

Answers

Evolution is defined as  gradual change to the DNA of a species over many generations.

Palaeoanthropology is the scientific study of human evolution

Human evolution is the lengthy process of change by which people originated from apelike ancestors

It can occur by natural selection, when certain traits created by genetic mutations help an organism survive/reproduce. These mutations will pass onto next generation.  

On our recent study of DNA, we can see evidence that natural selection has recently made changes, so evolution will never stop.

There are several signs of human evolution-

1. The adaptation to the threat of infectious diseases and High prevalence of diseases like  sickle cell disease and thalassemias

2. Also. deviations from expected allele frequencies provide clues that genes have undergone selection.

Human activity has altered our atmosphere with time. Also,  humans now have the capability to take a direct hand in evolution of species it  includes with  artificial selection , animal and plant breeding, genetic engineering and genome editing etc.

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Which group of microbes must have oxygen to grow although they are deficient in the defense systems needed to quench the toxic, partially reduced intermediates of this element?.

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Microaerophiles are group of microbes must have oxygen to grow .

Microaerophiles are those microbes, that require oxygen for growth, are unable to grow at normal atmospheric oxygen tensions, they also adopt particular environment with low oxygen tension .

Microaerophiles need oxygen because they cannot ferment or respire anaerobically. They Produce ATP via aerobic respiration or fermentation. Microaerophiles gets poisoned by high concentrations of oxygen. for example Lactic acid bacteria (LAB) are well defined as a group of microaerophilic.

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The ______ functional division of the nervous system transmits information from the viscera to the central nervous system.

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The visceral functional division of the nervous system transmits information from the viscera to the central nervous system.

The afferent or sensory department transmits impulses from peripheral organs to the CNS. The efferent or motor department transmits impulses from the CNS out to the peripheral organs to purpose an impact or action.

The 2d principal department of the frightened system, the peripheral frightened system, consists of messages to and from the imperative frightened system. It includes all the nerve cells that aren't withinside the mind or spinal column. It is constituted of parts: the somatic and the autonomic frightened systems.

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Many cell phone users are reluctant to change platforms because they do not want to learn a new system. Marketers could overcome this resistance with_______. hree students are participating in a walkathon. The data for each student is shown.Student A: The equation y = 13x represents the amount of money raised (y) for walking (x) miles.Student B: $36 is raised after walking 3 miles.Student C:Miles Walked 4 5Money Raised $52 $65Determine which student raised the least amount of money after walking 7 miles. Student A Student B Student C All three students raised the same amount of money after walking 7 miles. what part of an expert system provides the reasoning capability, namely the ability to answer users' questions, provide recommendations for solutions, generate predictions, and conduct other relevant tasks? a pharmaceutical representative has given you a series of $20 gifts over the course of 1 year with a total value at $60. according to the government ethics guideline what must you do? proof that (x-1/x)(x^4/3+x^2/3) = x(x-1/x) which traditional/mass effects view of audiences suggests that media messages are filtered through opinion leaders? Devontae claimed that the line y=-3/4x forms an angle of about 53.13 with the positive x-axis. Which statement proves his claim correct or incorrect? a) Correct because arctan(4/-3) = -53.13 b) Correct because arccos(-3/4) = 53.13 c) Incorrect because arctan(-3/4) = -36.87 d) Incorrect because arccos(-3/4) = -138.59 in mice, the copy of the igf 2 gene that is inherited from the mother is never expressed in her offspring. this happens because the igf 2 gene from the mother a. always undergoes a mutation that inactivates its function. b. is deleted during oogenesis. c. is deleted during embryonic development. d. is not transcribed in the somatic cells of the offspring. your enterprise ran out of computing resources due to the increasingly high rate of stored data. you are asked to choose a cloud model in which your enterprise can have the most control over the hardware. which model should you choose? in us elections, pac funding helps shape electoral outcomes by tending to favor which type of candidate? Find the value of x. Then find the measure of each labeled angle.(x - 58) =(x-58) Hunter bought 3 chicken wings for $6.60. How much does each wing cost? Suppose that 12 inches of wire costs 36 cents. At the same rate, how many inches of wire can be bought for 21 cents? Why is guzzo so upset with Quinn and Jill? Is he right to be upset ? A window in the room has an actual width of 2. 5 feet. What is the width of the window in the blueprint? (same scale 3 in:5 ft) The experience of women in the revolution has influenced heavily both mens and womens attitudes toward women, especially regarding womens work and leadership capacities. Women look back upon the revolution as a time of awakening. (One woman relates that) when the Frente Sandinista beganwomen also within the linesfought the role of men; that is when the women realized that we can work the same as a man, that we can develop equally as a manThey were heroines. They showed us, they gave us really an idea that the women in the world, in life, can work, can be equal to a man in work.a. Identify and explain one historically specific example of womens roles during the period 1900 to the present that would support the authors argument.b. Identify and explain one historically specific example of womens roles in the period BEFORE 1900 that would support the authors argument.c. Identify and explain one development in the late 20th century that likely explains the historians interest in the subject of the passage. HELPP!!! Write a system of equations to describe the situation below, solve using substitution, and fill in the blanks. A business owner wants to have the front window of her store painted and is considering two artists for the job. Grace has quoted a flat rate of $99 for the job. Eva's quote is $10 per hour, plus $89 to cover the cost of materials. Depending on how long it takes Eva to paint the window, these two could end up charging the same amount. How much would it cost? How long would Eva have to take? You hav Vide Are the slopes 0/3 and 9/0 perpendicular? Explain Descriptive essay on A place you visited 3-5 pages a rotating wheel requires s to rotate revolutions. its angular velocity at the end of the -s interval is rad/s. what is the constant angular acceleration (in ) of the wheel?