Silent mutations are mutations in DNA that do not have an observable effect on the organism’s phenotype.
They are a specific type of neutral mutation. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation; however, synonymous mutations are not always silent, nor vice versa. Synonymous mutations can affect transcription, splicing, mRNA transport, and translation, any of which could alter phenotype, rendering the synonymous mutation. The substrate specificity of the tRNA to the rare codon can affect the timing of translation, and in turn the co-translational folding of the protein. This is reflected in the codon usage bias that is observed in many species. Mutations that cause the altered codon to produce an amino acid with similar functionality (e.g. a mutation producing leucine instead of isoleucine) are often classified as silent; if the properties of the amino acid are conserved, this mutation does not usually significantly affect protein function.
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What is the importance of haploid?.
The improvement of plant or crop output is the main benefit of haploid plant production. Additional genetic variability is produced as a result of soma clonal variation.
Only the egg and sperm cells in humans are haploid. Male and female gametes that are fused together by haploid gametes produce a diploid zygote, which has the same number of chromosomes as its descendants. Because they have a single set of chromosomes, haploid cells are the best specimens to use for genetic testing. Haploid cells make it more simpler to develop homozygous mutants, which are necessary for the study of recessive traits, compared to diploid cells.
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Identify the events in the cell cycle that must be completed successfully for daughter cells to share an identical complement of chromosomes. Check all that apply. A) the spindle apparatus must connect with the ends of each sister chromatid in pro metaphase; B) the sister chromatids of each replicated chromosome must be partitioned in anaphase and fully separated into daughter cells by cytokinesis; C) the spindle apparatus must connect with the kinetochores of each sister chromatid in pro metaphase; D) the sister chromatids of each replicated chromosome must be partitioned in the G2 phase and fully separated into daughter cells by cytokinesis; E) all the chromosomes must be replicated during the prophase; F) all the chromosomes must be replicated during the S phase
The correct answers are option B, C and F.
The events in the cell cycle that must be completed successfully for daughter cells to share an identical complement of chromosomes are replication of chromosomes during S phase, spindle fiber meets kinetochores in pro-metaphase, partition of sister chromatids in anaphase and formation of new daughter cells during cytokinesis.
The detail of each step is given below.
The sister chromatids of each replicated chromosome must be partitioned in anaphase and fully separated into daughter cells by cytokinesis.
The spindle apparatus must connect with the kinetochores of each sister chromatid in pro metaphase.
All the chromosomes must be replicated during the S phase.
Hence these are the events in the cell cycle that must be completed successfully for daughter cells to share an identical complement of chromosomes.
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what was the most likely purpose of adding bovine serum albumin to the kinetics experiments in the passage? bovine serum albumin:
The reaction's co-catalyst is bovine serum albumin.
The function of bovine serum albuminBovine Serum Albumin binds to and transports between tissues and cells water, salts, fatty acids, vitamins, and hormones due to its negative charge. Bovine Serum Albumin's binding ability also makes it a potent scavenger, removing poisonous substances from the medium, including pyrogens.
In cell and microbial culture, BSA is employed as a nutrient. BSA is a chemical that is used in restriction digests to stabilize some enzymes while they break down DNA and prevent the enzyme from sticking to pipette tips, reaction tubes, and other vessels.
A component of the whey portion of cow's milk, BSA is a protein that is primarily found in the circulatory system of the cow.
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What are the food safety practices?.
Keep clean, separate raw from cooked food, cook thoroughly, maintain food at safe temperatures, and use safe water and raw materials are the five basic principles for producing safe and wholesome food safety practices
According to Dr. Enrique Perez, senior advisor for PAHO/WHO on food-borne diseases and zoonoses, following these five guidelines gives consumers confidence that they are handling food securely and preventing the spread of microorganisms. They can be used in both homes and restaurants because they are straightforward and useful food safety practices.
A third of foodborne illness outbreaks are traced to food cooked and consumed at home, and a sizable fraction of all cases are brought on by bacterial contamination as a result of a few risky behaviors.
Over 200 diseases, from diarrhea to cancer, are brought on by food tainted by bacteria, viruses, parasites, or dangerous chemicals. An estimated 35 million children under the age of five in the Americas experience these illnesses each year.
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In a mutation, which of the following types of cells is MOST LIKELY to be passed from a parent to its offspring?
A mutation in a skin cell due to ultraviolet (UV) light and not wearing sunscreen.
A mutation in a kidney cell due to a virus having the opportunity to enter the cell.
A mutation in a hair cell due to chemicals in hair care products.
A mutation in a sperm cell due to being a gamete required for reproduction.
The mutation that passes from the parents to the offspring is a mutation in a sperm cell due to it being a gamete required for reproduction. Out of all the other options, the last one is correct regarding the mutation.
What is mutation?Mutation can be of the somatic type, in which somatic cells change their genetic make-up (such as skin cells), or it can be a germline mutation, such as a mutation in the cells that form gametes. The somatic mutation cannot pass down as it does not involve gamete formation, but the germline mutation passes down to offspring as they form the gametes that later form the zygote.
Hence, the correct answer is the final /last option, which states "A mutation in a sperm cell due to being a gamete required for reproduction".
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arrange the order of events for the internalization of ldl particles into cells: ldl, made up of combination of cholesterol and apolipoprotein, binds to ldl receptors and becomes internalized as endocytotic vesicles. the environment of the endosome becomes acidic, which causes the ldl to dissociate from its receptor; additionally, the endosome fuses with a lysosome. several endocytotic vesicles fuse to form an endosome. the ldl particle is degraded by the lysosome. ldl receptors migrate to the cell surface and cluster in clathrin-coated pits. view available hint(s)for part a arrange the order of events for the internalization of ldl particles into cells: ldl, made up of combination of cholesterol and apolipoprotein, binds to ldl receptors and becomes internalized as endocytotic vesicles. the environment of the endosome becomes acidic, which causes the ldl to dissociate from its receptor; additionally, the endosome fuses with a lysosome. several endocytotic vesicles fuse to form an endosome. the ldl particle is degraded by the lysosome. ldl receptors migrate to the cell surface and cluster in clathrin-coated pits. 5-1-3-2-4 5-2-3-1-4 5-4-1-3-2 1-5-3-2-4
The correct order of events for internalization of LDL into cells is
5 - 1 - 3 - 2 - 4
To know the order of the process, read this following explanation.
How cells take up the LDL?Despite having a bad reputation as a high-risk factor for cardiovascular disease, cholesterol is an essential component. It is an integral part of cell membrane, also serves as a precursor of bile, Vit D and steroid hormones.
Cholesterol, together with other lipids, is transported in blood plasma within large particles known as lipoprotein which is an assembly of lipids and protein. Lipoprotein are classified based on their density, one of them is low density lipoprotein (LDL).
LDL carries cholesterol from the liver to other tissues. Peripheral cells take up LDL by endocytosis using LDL receptors. The process how cells take up LDL is described as follows :
LDL receptors migrate to the cells surface and cluster in Clathrin-coated pits.LDL binds to LDL receptors at the plasma membrane and the complex assembly in a coated pit.The internalized pit is converted into Clathrin-coated vesicle that fuses with endosomes after the Clathrin coat is removed. The LDL dissociates from its receptor in the acidic environment of the endosomes and degraded in lysosomes.Learn more about LDL internalization by clicking this link https://brainly.com/question/13650088
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Water is buoyant and so provides support to plants living in the water. For plants to invade land, what would be needed to help address this issue?
A. exoskeleton
B. waxy cuticles
C. rigid structures
D. photosynthesis
C. rigid structures
Rigid structures, helps the plants be held up and sustain environmental conditions
What developed in terrestrial plants to sustain and move minerals and water?The "piping system" of a plant is made up of vascular tissues. For photosynthesis, they transport water and minerals from the soil to the leaves. Additionally, they transport nutrients (sugar dissolved in water) from photosynthetic cells to other cells in the plant for storage or growth. The development of vascular tissues transformed the realm of plants.
How does the cuticle of a plant enable it to survive on land?Plants had to change over time in order to transition from aquatic to terrestrial life. Early plants developed a waxy layer called a cuticle to help retain water and stop water loss. The cuticle, however, also hinders gases' easy entry and exit from the plant.
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for crossing over to occur, homologous chromosomes must align precisely early in prophase i so that nonsister chromatids can exchange corresponding segments of dna. blank target 1 of 4 as a result of crossing over, sister chromatids are no longer identical to each other. blank target 2 of 4 crossing over occurs at the ends of chromosomes, rather than near the centromeres. blank target 3 of 4 crossing over prevents homologous chromosomes from separating during meiosis i. blank
The correct statements about crossing over are
1. For crossing over to occur, homologous chromosomes must align precisely early in prophase I so that non-sister chromatids can exchange corresponding segments of DNA.
2. Crossing over occurs at the ends of chromosomes, rather than near the centromeres because segments of DNA near the centromeres cannot break and rejoin easily.
Thus, the correct statements are numbers 1 and 2.
What is crossing over?Crossing over is unique to meiosis. Its occurrence depends on specific events early in prophase I and it has important consequences for the rest of meiosis and beyond.
Crossing over occurs during prophase I when homologous chromosomes loosely pair up along their lengths. Crossing over occurs only between non-sister chromatids within a homologous pair of chromosomes, not between the sister chromatids of a replicated chromosome. Only segments near the ends of the chromatids, not segments nearest the centromeres, can exchange DNA.
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What are the factors that influence premarital sex?.
Age, sex, peer relationship, peer pressure, love and affairs are the important factors that influence premarital sex.
Premarital sex defined as sexual intercourse before marriage.
Youths and adolescents are the most vulnerable group of premarital sexual behaviour.
Age, sex, relationship, peer pressure, love and affairs are the important factors that influence premarital sex.
The premarital sexual practice among the students was affected by the factors including -
the living arrangements, sexual health education, and alcohol consumption.
Premarital sex can lead to various issues including- pregnancy, abortion, damage of uterus, drop out of school and it can also affect future marriages.
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streptococcus pyogenes is inoculated to a blood agar plate with a taxo a disc. you should expect to see:
After applying the disk and allowing it to incubate, you can see the zone of growth inhibition, meaning that there is no bacterial growth around the disk.
What suggests that a blood agar plate contains Streptococcus pyogenes?Blood agar plates are examined for the presence of colonies of -hemolytic bacteria in order to recognize S. pyogenes in clinical samples. S. pyogenes colonies typically have a dome-shaped, smooth or moist surface, and clear margins after 24 hours of incubation at 35-37°C.
You should anticipate seeing by the sensitivity to bacitracin if Streptococcus perogenous is inoculated to a blood agar played with a tax or a disk. Streptococcus perogenius can be distinguished from other non-group A strains, as is well known. However, due to their increased sensitivity to etc., the hemolytic streptococcus. As you can see, a plate, a guard, and some bacterial manipulation are present.
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an mrna is expressed that begins with the sequence augccaggcguc. using the genetic code below, determine what peptide will be translated from this mrna.
Peptide mRNA AUGCCAGGCGUC will be translated into Methionine-Glycin-Proline-Valine.
RNA stands for ribonucleic acid which is one of the genetic materials that is made up of nucleotides. In the human body, RNA acts as a carrier of genetic information and translates it into the synthesis of various kinds of proteins.
RNA can be divided into three types:
mRNA (messenger RNA), serves to carry the genetic code (codons) from the chromosomes in the cell nucleus to the ribosomes in the cell cytoplasm.rRNA (ribosomal RNA), serves as an alignment (adapter) or polypeptide assembly machine that moves in one direction along the mRNA during protein synthesis.tRNA (transfer RNA), functions to carry amino acids to the ribosome to translate the codons of the mRNA.Learn more about RNA at https://brainly.com/question/28073947
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What is somatic and examples?.
The main purpose of the somatic nervous system is to connect the central nervous system with the body's muscles to balance voluntary movements and reflex arcs.
Here is an example: You are out for a jog in the park one brisk winter morning. As you run, you spot a patch of slick ice on the path ahead.
this species was bipedal but kept several ape-like characteristics such as adaptations for tree climbing, a tiny brain, and a large mouth. many cranial traits, such as a low, sloping forehead, a projecting face, and pronounced brow ridges above the eyes, were ape-like. another thing we can learn is the anatomy of the knee joint indicated that it belonged to a species that walked on two legs, and it was the oldest evidence of a biped at the time.
Australopithecus afarensis species was bipedal but kept several ape-like characteristics such as adaptations for tree climbing, a tiny brain, and a large mouth.
An extinct species of australopithecine known as Australopithecus afarensis flourished in the Pliocene of East Africa between 3.9 and 2.9 million years ago.
They were bipedal, meaning they moved on two legs, like modern humans, but unlike apes, they had small brains. Their cheek teeth were bigger than those of modern humans, but their canine teeth were smaller than those of apes.
Africanus possessed certain ape-like characteristics, such as relatively long arms and a sharply sloping face that protrudes from behind the braincase with a noticeable jaw. It also had a rounder cranium that housed a larger brain and smaller teeth.
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determine whether each description pertains to driver mutations and passenger mutations. drag and drop each description to the appropriate category.
Oncogenes: Cancer is caused by activation of oncogenes and involves gain-of-function. Usually, a point mutation, translocation, or inversion is linked to activation.
cancer-suppressing genes Cancer results from a loss-of-function that is frequently caused by a point mutation or deletion, and inactivation causes cancer.
What exactly are passenger and driver mutations?Drivers are characterized as mutations that give somatic cells a competitive advantage in their microenvironment, causing the cell lineage to diverge into cancer. On the other hand, mutations that do not have this proliferative benefit are referred to as passengers (also known as "hitchhikers").
A driver mutation must have existed at some point during a cancer's evolution even though it is not necessary for the cancer to continue to grow. Cancer genomes contain passenger mutations because they frequently arise during somatic cell division and have no functional consequences.
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Membrane curvature is influenced by the differential lipid composition of the two membrane monolayers. Which factor do you think has the largest impact on the curvature of biological membranes?.
The distribution of cholesterol in the lipid bilayer's two halves. The largest impact on the curvature of biological membranes.
Cholesterol is rather frequently found in this bilayer in a "flipped" shape, with the hydroxyl group facing the membrane middle plane. Additionally, this bilayer has the lowest reorientation barrier and maximum (least negative) binding free energy among liquid phase bilayers.
The permeability-barrier qualities of the lipid bilayer are improved by the cholesterol molecules. Their hydroxyl groups are positioned near to the polar head groups of the phospholipid molecules as they are oriented in the bilayer.
There has been a lot of interest in the function of cholesterol in lipid membranes including bilayers and monolayers. By generating liquid-ordered-phase lipid rafts, cholesterol dramatically improves the order of lipid packing, reduces membrane permeability, and preserves membrane fluidity on a biophysical level.
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If a purple-flowered, heterozygous plant were crossed with a white-flowered plant, what is the expected ratio of genotypes among the f1 offspring? suppose p is a dominant allele for a flower color and p is a recessive one.
Heterozygous Purple flower - Pp
Gametes : P and p
Recessive white flower: pp
Gametes: p
Fusion thus yields: Pp (Purple) and pp (white)
The ratio is 1:1
Hence, it is 50% purple and 50% white.
What is Cross-Pollination?
Cross pollination occurs when pollen from one plant's flower combines with pollen from another plant's flower. In nature, pollen is typically carried from one plant to another by wind and insects such as bees.
The pollen is what causes the plant to produce seeds, which will eventually grow into a new generation of the species.
The characteristics of both parent plants are typically present in first generation hybrids. However, future generations will be less consistent with their new traits.
A new species can take 5 or more generations of careful hybridization breeding to stabilize. This is why, if you take the seeds from a first generation hybrid fruit (for example, a tomato variety you like from the store) and grow them at home, you may not get the fruits you expected.
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the tca cycle produces multiple choice atp, fad, and precursor metabolites nadh, atp, and fad. fadh2, nadh, and precursor metabolites. fadh2, adp, and nadh. precursor metabolites, nad, and fadh2.
FADH2, NADH, and precursor metabolites are produced through the TCA cycle.
After being created throughout the TCA cycle, where do NADH and FADH2 go?In the cell membrane of prokaryotes or the inner membrane of eukaryotes, NADH and FADH2 travel to the electron transport chain. The TCA cycle occurs in the mitochondria of prokaryotes and eukaryotes.
What is created throughout the TCA cycle?Acetyl CoA and oxaloacetate undergo an enzymatic aldol addition process to generate citrate at the start of the TCA cycle. By use of a dehydration-hydration process, the citrate is isomerized to produce (2R,3S)-isocitrate. The product of additional enzymatic oxidation and decarboxylation is 2-ketoglutarate.
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describe both the structural organization of the nervous system and the functional organization of the nervous system
The brain, spinal cord, and cerebellum make up the CNS. Sensory input, information processing, and motor output are the three main tasks performed by the nervous system.
What are the nervous system's structural and functional components?The building blocks and active components of the nervous system are called neurons. There are billions of neurons in the neurological system. A neuron, also known as a nerve cell, is a type of cell found inside the body that receives, processes, and sends information via chemical and electrical signals.
What do the nervous system's functional units look like?The fundamental units of the nervous system, called neurons, produce electrical signals called action potentials that enable them to rapidly transfer information.
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Emphysema causes a loss of walls between individual alveoli, resulting in fewer, but larger, alveoli. Which part of gas diffusion would be most affected by emphysema?.
Emphysema causes a loss of walls between individual alveoli, resulting in fewer, but larger, alveoli. Surface area part of gas diffusion would be most affected by emphysema.
What do you mean by emphysema?A condition that affects the lungs' tiny air sacs, or alveoli. In the alveolar walls of the lungs, oxygen and carbon dioxide are transferred. Emphysema causes the alveoli to expand abnormally, weakening their walls and making breathing more difficult. Smoking (the main cause) (the main cause) exposure to air pollution, which includes exposure to dust, chemical fumes, and other chemicals dust and odors at work that are irritating. Alpha 1-antitrypsin (AAT) deficiency-related pulmonary emphysema, also known as early onset pulmonary emphysema, is a rare, inherited variety of the condition.
How does emphysema affect surface area?Alveoli, the lungs' air sacs, suffer damage in those with emphysema. The air sacs' inner walls deteriorate and tear over time, resulting in the creation of fewer, larger air gaps as opposed to more, smaller ones. As a result, less oxygen enters your bloodstream because of a reduction in lung surface area.
Thus from above conclusion we can say that emphysema causes a loss of walls between individual alveoli, resulting in fewer, but larger, alveoli. Surface area part of gas diffusion would be most affected by emphysema.
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a(n) is an assemblage of populations of multiple species, interacting with one another within a single environment.
A community is an assemblage of populations of multiple species, interacting with one another within a single environment.
Community, also known as a biological community, is a group of interacting organisms species or populations of multiple species that share a similar habitat in ecology. A biological community is made up of things like a forest of trees and underbrush plants that is home to various animals and is anchored in bacterial and fungal-rich soil.
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from your general biology knowledge, if an mrna (sense) is mixed with another matching sense oligonucleotide, what will happen?
Nothing will happen if an mRNA (sense) is mixed with another matching sense oligonucleotide.
A DNA is double-stranded whereas an mRNA is single-stranded. A DNA molecule needs to form a complementary strand if another matching oligonucleotide strand is found.
However, mRNA being single-stranded does not require any other matching sense oligonucleotide.
The information in an mRNA will be decoded by amino acids rather than oligonucleotides. The information of the mRNA is such that a strand of amino acids that makes proteins will be generated from it and hence sense oligonucleotide will do nothing.
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in the figure above, what letter corresponds to the light-sensitive surface of the eye that contains photoreceptors?
in the figure attached, the letter that corresponds to the light-sensitive surface of the eye that contains photoreceptors is D.
What are the photoreceptors in the human eye?Cones and rods, two different types of photoreceptors, are found in the retina. Cones are in charge of vision during the day, whereas rods are in charge of seeing at night.
Light is transformed into signals that are transmitted to the brain by specialized cells in the retina of the eye. Our night vision and color vision are both provided by photoreceptors. Rods and cones are the two different types of photoreceptor cells. Photoreceptor cells can be involved in a variety of eye issues.
The clear cornea of the eye allows light to enter, which then travels through the aqueous humor, lens, and vitreous humor before forming a picture on the retina.
Hence, The retina of the human eye creates a true, inverted image. It results from the use of a convex lens.
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Which of the following statements regarding fungi is FALSE?A) Most fungi are pathogenic for humans.B) Fungi are eukaryotic heterotrophs.C) Fungi reproduce by forming asexual or sexual spores.D) Most fungi grow well in acidic culture condition.E) Fungi tolerate low moisture conditions.
The correct answer is A : Most fungi are pathogenic for humans. Although the great majority of fungus lack pathogenic characteristics, certain species can infect people with diseases that can range from mild to fatal. In addition, a few fungal species are plant diseases that have a terrible effect on agriculture.
Only a small number of the estimated 1.5–5.0 million fungal species on Earth (O'Brien et al. 2005) are able to infect healthy individuals, and only a small number of them cause illness in humans.
Fungi have significant roles in biomedical research, manufacturing, and industrial sectors, and they have an impact on human behavior through their effects on agriculture, world health, and biodiversity. On the earth, fungi have been found in practically every type of habitat, including air, soil, fresh water, and the seas.
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which is not a pathogen? question 3 options: hookworm athlete's foot fungus chicken pox virus meningococcus bacterium cancer
The parasite hookworm is not regarded as a disease. Ascaris, whipworm, and hookworm are examples of helminths that are spread through soil (parasitic worms).
Organisms, which do not cause diseases are called non-pathogenic .Antibodies are highly specific for one particular antigen, and only develop in the body after previous exposure to a pathogen It is thus not regarded as inherent. A portion of the initial line of defense against diseases is skin, tears, and mucus. They aid in defending us against encroaching infections. On the skin, in your bowel, and in other parts of your body (such as your mouth as well as the stomach), there are healthy bacteria that prevent other, bad germs from taking control. Pathogens come in a variety of forms, but we'll concentrate on the four most prevalent: viruses, bacteria, fungus, and parasites. Pathogens come in a variety of forms, but we'll concentrate on the four more prevalent: virus, bacteria, fungus, and parasites.
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The concentration of free Ca2+ in the cytosol of an unstimulated cell is kept low compared with its concentration in both the extracellular fluid and the endoplasmic reticulum. Which of the following help to maintain this difference?
Ca2+ siphons in the ER membrane and Ca2+ siphons in the plasma membrane are the right response.
Calcium Siphons are protein pumps that move Ca2+ back into the sarcoplasmic reticulum (a changed Endoplasmic Reticulum) in skeletal muscle after every constriction. They have a place with the particle carriers protein family.
In calcium homeostasis, these siphons are essentially particle carriers situated on the cell film of every single creature cell. They help to siphon Ca2+ out of the cell to keep up with electrochemical angles across the cell membrane.
The rough and smooth endoplasmic reticulum, the smooth resembles a fine cylinder while the rough comprises ribosomes on its surface. Both the smooth and rough endoplasmic reticulum cooperate, delegate undertakings, and are the site for the creation and capacity of proteins. The smooth endoplasmic reticulum is answerable for stockpiling and lipids creation, while the rough endoplasmic reticulum is liable for the development of proteins and a few chemicals.
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what structural feature makes an enzyme or antibody different from a silk protein? please choose the correct answer from the following choices, and then select the submit answer button. answer choices
Inhibitory antibodies, Antibodies may precisely bind a wide variety of chemical compounds using the same kinds of molecular interactions as enzymes.
What is the Enzyme's Structure?Except for ribozymes, the majority of enzymes are proteins (composed of RNA). They are specific and have a tertiary structure in three dimensions. Peptide chains are repeatedly folded or supercoiled to create fissures or pockets to generate tertiary structure.
What is the protein structure of silk?Due to their distinctive structure, silk proteins form a distinct class of naturally occurring fibrous proteins. Many silks have long domains of hydrophobic amino acids that are separated by shorter, more hydrophilic sections. This makes up their molecular structure.
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Essays 1. Suppose a researcher for a pest-control company developed a chemical that inhibited the development of an embryonic mosquito's endodermal cells. Which of the following would be a likely mechanism by which this pesticide works? What does the endoderm turn into? A mosquito would have trouble digesting food due to impaired gut function.
The mosquito would become more prone to injury due to a weakening of its Exoskeleton.
Exoskeleton, a hard or flexible covering that supports and shields an animal's soft tissues. The phrase refers to the chitinous integument of arthropods, such as insects, spiders, and crustaceans, and includes the calcareous housings of sessile invertebrates like clams. The exterior waxy, water-resistant covering of the arthropod exoskeleton, which is made from the epidermis, is covered by chitinous, and flexible layers. This coating features tiny breathing openings in terrestrial species (spiracles). The exoskeleton has made it possible for arthropods, particularly insects, to overrun the majority of terrestrial ecosystems by avoiding dehydration. Exoskeletons of animals like the lobster have flexible joints that allow for remarkable mobility.
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What is the codon for the DNA strand CGA?.
The DNA strand CGA has the codons CGA, CGG, CGU, and CGC.
What does DNA's codon code look like?Codons are units of genomic information made up of three nucleotides (trinucleotides) in DNA or RNA that code for a specific amino acid or indicate the end of protein synthesis (stop signals). Codons contain 64 distinct elements, of which three act as stop signals and 61 function as amino acid identifiers.
Is the start codon CAG?Mammalian cells can start translation using leucine utilising a particular leucyl-tRNA that decodes the codon CUG in addition to the standard Met-tRNA Met and AUG codon route. The CAG start codon is used by Candida albicans.
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Damage associated with free radicals, highly unstable oxygen atoms formed during metabolism, has been mentioned as a factor in all of the following EXCEPT
Select one:
a. neurological disorders.
b. genetic disorders.
c. muscular dystrophy.
d. late-onset diabetes.genetic disorders
Damage associated with free radicals, highly unstable oxygen atoms formed during metabolism, has been not mentioned as a factor in genetic disorders.
What is metabolism?
The group of chemical processes in organisms that maintain life is known as metabolism. The three primary functions of metabolism are: converting the energy in food into energy that can be used to power cellular functions;
What is genetic disorder?A genetic disorder is a condition that is wholly or partially brought on by a deviation from the typical DNA sequence. A single gene mutation (monogenic disorder), numerous gene mutations (multifactorial inheritance disorder), a combination of gene mutations and environmental factors, or chromosome damage can all result in genetic illnesses (changes in the number or structure of entire chromosomes, the structures that carry genes)
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Gene knockout in mouse A. Outline the sequence of steps necessary to generate a gene knockout in the mouse. Be sure to include the information you need to start the procedure. B. The targeted insertion of your transgene in embryonic stem (ES) cells has a very low probability of success (roughly 1 in 10,000 cells tested). Based on what you know about molecular biology, why is the probability of success so low for this step? What feature of the procedure makes it viable despite the low probability of success at this step?
Steps necessary to generate a gene knockout in the mouse: targeting vector → electroporated into ES cells → culture ES cell → correctly targeted ES cell → selected ES cell clone → identify chimeric mice → target allele were identified.
The probability of success is very low for this step as the process is completely random and there is low or no specificity to the site where the actual crossing process occurs
The procedure that makes it feasible despite the low probability of success at this step is that the addition of two marker gene sequences makes it possible to detect successful homologous recombination processes.
Strains of mice in which certain genes from their genome have been disrupted, or "knocked out". To produce a knockout, using recombinant DNA technology, the normal DNA sequence of the gene being studied is altered to prevent the synthesis of the normal gene product. cloned cells in which this DNA change was successful were then injected into mouse embryos to produce chimeric mice. Chimeric mice were then bred to produce a strain in which all mouse cells contained the disrupted gene. knockout mice are used as experimental animal models for disease (disease models, animals) and to clarify gene function.
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