what techniques could be used to demonstrate that a mutation in a man with hemophilia is due to the insertion of an alu element into the coding sequence of the x-linked gene for factor viii, one of the proteins needed for efficient blood clotting in humans?

Answers

Answer 1

Therefore, if a guy inherits an X chromosome that has a mutation in either the factor VIII or factor IX gene, they may develop a disease similar to hemophilia. Hemophilia can also affect women, however this is far less common. In these situations, either both of the X chromosomes are afflicted, or one is affected while the other is absent or inactive.

What is Mutation ?

A mutation in biology is an adjustment to the nucleic acid sequence of an organism's, virus's, or extrachromosomal DNA. DNA or RNA can be found in the viral genome.

Mutations that are harmful can result in cancer or genetic diseases. A genetic disorder is a condition brought on by a change in one or more genes. Cystic fibrosis is a human example. A single gene mutation causes the body to create thick, sticky mucus that obstructs digestive organ ducts and clogs the lungs.

Missense, nonsense, insertion, deletion, duplication, and frameshift are just a few categories of gene mutations. The advent of lethal diseases like cancer is one of the main consequences of a gene mutation.

What is Hemophilia ?

An genetic bleeding ailment called hemophilia causes the blood to clot improperly. This may result in both spontaneous bleeding and bleeding after injury or surgery. Blood contains a variety of clotting proteins that can aid in halting bleeding.

A moderate form of hemophilia A or B usually results in substantial bleeding after an accident. Additionally, you can have bleeding after an injury if you have hemophilia A or B in its most severe forms. spontaneous bruising of the muscles or joints

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Related Questions

some substances are not normal components of urine because they are completely reabsorbed. choose the substances that satisfy this requirement under healthy conditions. multiple select question. hydrogen ions calcium ions sodium ions glucose lactate amino acids filtered plasma proteins

Answers

The substances that satisfy the requirement are Glucose , amino acids and sodium ions

Water makes up 95 percent of human urine. The remaining components include minor amounts of urea (2%), creatinine (0.1%), uric acid (0.03%), chloride, sodium, potassium, sulphate, ammonium, and phosphate, as well as other ions and molecules.

The substances like glucose, amino acids, Na+ etc., in the filtrate

are reabsorbed actively

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nuclieotide that is substituted for thymine in an rna molecule

Answers

Explanation:

uracil.

uracil is present in RNA instead of thymine.

A mineral is able to scratch your fingernail but not glass. We can conclude:
Group of answer choices

the mineral is harder than your fingernail but softer than the glass

the mineral will exhibit cleavage

the mineral was once an igneous rock and is therefore hardened lava

the mineral is softer than your fingernail but harder than the glass

Answers

Answer:

the mineral is softer than your fingernail but harder than glass

Explanation:

i think that's the answer

once threads form, they stick to the exposed surface of damaged blood vessels creating a meshwork that entraps blood cells and platelets. this meshwork is called a .

Answers

Fibrin stick to the exposed surface of damaged blood vessels creating a meshwork.

The fibrin, an insoluble protein that is created in reaction to bleeding and serves as the main component of the blood clot, is caught in a meshwork that is formed when they adhere to the exposed surfaces of damaged blood vessels.

It is made of fibrinogen, a soluble protein produced by the liver and present in blood plasma, which is a stiff protein material that is structured in long fibrous chains.

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for each of the following pedigrees, determine: i) the most likely mode of inheritance (recessive or dominant, x-linked, y-linked or autosomal) ii) the genotype of the individual marked with a star assume that individuals marrying into the family do not have the defective allele. explain your reasoning. clearly define any symbols that you use.

Answers

The most likely mode of inheritance is x-linked inheritance as only the mother is affected.

The genotype of the individual marked with a star is XDXd.

When analyzing a family, autosomal dominant inheritance can be recognized by the vertical transmission of the trait—from parent to child.

There's a subtlety in overwhelming inheritance—formally a characteristic is called autosomal dominant as it were when the phenotype of the heterozygote is the same as the homozygous variant.

It isn't as a rule conceivable to run the show out of an autosomal legacy to affirm X-linkage. In any case, certain designs unequivocally recommend X-linkage.

This is often because all male siblings would acquire the latent allele from their mother (and be XY) whereas all female descendants would acquire the overwhelming allele from their father (and be XDXd).

For illustration, a family where a male parent without the characteristic (XDY) and a female parent communicating the characteristic (XdXd) with 100% male expression and 0% female expression infers X-linkage.

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Although part of your question is missing, you might be referring to this full question:

For each of the following pedigrees, determine i) the most likely mode of inheritance (recessive or dominant, x-linked, y-linked, or autosomal) ii) the genotype of the individual marked with a star assume that individuals marrying into the family do not have the defective allele. explain your reasoning. clearly define any symbols that you use.

how were terrestrial environments occupied by vascular plants and animals, including tetrapods during middle paleozoic

Answers

Terrestrial animals' adaptations include body weight, protection, and humidity. Vascular plants thrive because they can transfer water, nutrients, and seeds more effectively.

The Age of Fishes corresponds to the middle Paleozoic.

True roots consisting of vascular tissues have emerged in vascular plants. Rhizoids can absorb less water and minerals from the soil than roots can. All terrestrial plants share four main adaptations: a sporangium where spores are made, a gametangium where haploid cells are produced, and apical meristem tissue in roots and shoots.

Tetrapod species developed seven or more vertebrae, which increased neck movement, as they continued to evolve on land. Early tetrapods' shoulders and pelvis grew and developed, enabling them to carry loads on land. Different skeleton and muscle adaptations that allow for proper support and movement on land.

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You are designing a gene therapy to replace a defective fibrillin gene, which is 22,000 bp long and is important in preventing macular degeneration. Based on your knowledge and resources available from class, which vector is best to use?.

Answers

Adenovirus Vector is best to use in this case which is about 22,000 bp long and is also important in preventing macular degeneration.

In molecular biology research, a viral vector is a genetic sequence derived from a virus, such as an adenovirus, that is utilized to express a specific nucleotide sequence, in this case, the fibrillin gene used in gene therapy.

As a result of these findings, we can see that an adenovirus, for example, maybe the most effective viral vector for expressing nucleotide sequences longer than 20 kb.

The majority of adenoviruses cause respiratory disease. The diseases include bronchitis, pneumonia, croup, and colds. Adenoviruses, depending on the kind, can also lead to additional conditions such as gastroenteritis, conjunctivitis, cystitis, and, less frequently, neuropathy. Most infections with adenoviruses last between a few days and 1-2 weeks. Severe infections can linger longer and produce symptoms that recur such as coughing. For instance, when changing an infected person's diaper, some adenoviruses can spread through feces. Although it happens very seldom, adenoviruses can also spread through water or in swimming pools.

The complete question is:

You are designing a gene therapy to replace a defective fibrillin gene, which is 22,000 bp long and is important in preventing macular degeneration. Based on your knowledge and resources available from class, which vector is best to use?

(A). Cosmid

(B). Ri plasmid

(C). Ti plasmid

(D) Adenovirus

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1. Explain why DNP is effective at preventing the production of ATP in cellular
respiration and photosynthesis. Specify the relevant reactions in
photosynthesis and cellular respiration.Reference any sources that you consulted in composing your response.

2. Given the number of deaths caused by DNP, should it still be allowed to be sold as a commercial herbicide? Support your answer by including the risks and benefits of DNP.

ANSWER BOTH PLEASE THANK YOU

Answers

DNP functions as a protonophore, allowing protons to pass through the inner mitochondrial membrane and bypass ATP synthase. This reduces the efficiency of ATP energy production.

What is DNP?

2,4-dintrophenol (DNP) aids in the movement of protons across cell membranes, resulting in a decrease in ATP production (adenosine triphosphate, the molecule that transports energy within cells).

DNP acts as a protonophore, allowing protons to bypass ATP synthase by passing through the inner mitochondrial membrane. This reduces the efficiency with which ATP energy is produced.

As a result, the proton gradient cannot form across the inner mitochondrial membrane because H+ (hydrogen ion) pumping is halted. As a result, the pH across the inner membrane of mitochondria will decrease.

DNP is toxic to humans and can result in death as well as serious physical side effects. In the United Kingdom, selling DNP for human consumption is a crime.

Thus, it is dangerous to use DNP.

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4. Identify possible solutions (for hurricanes).

Solution #1:
Solution #2:
Solution #3:
Solution #4:
Solution #5:

Answers

Hello..!

4. Identify possible solutions (for hurricanes).

Not burningDo not litternot felling treesDo not throw waste into the seaSave water (No votes a lot)

I don't know if you meant that and if not here is another way :v

Buy your groceries before the hurricaneDo not leave homeIf you are in the hurricane keep calmProtect your house with anticyclonic curtains.Have emergency lamps.

I hope those of the 2 have served you.

Greetings.

how do sound waves ultimately result in the production of receptor potentials? group of answer choices the tectorial membrane squeezes the auditory nerve the basilar membrane releases neurotransmitters the eardrum has receptors that create action potentials hair cells in the cochlea vibrate, causing ion channels to open in their membrane

Answers

Hair cells in the cochlea vibrate, causing ion channels to open in their membrane

The hair cells in the organ of Cochlea convert the vibrations of mechanical sound into nerve impulse. The vibration of the basilar membrane, on which the organ of Corti is resting, stimulates them. The endocochlear potential, which exists between the endolymph and perilymph, is one of the most significant aspects of this process of conversion of sound into an electrical impulse by hair cells.

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Current climate change is part of normal fluctuation over time.

True
False

Answers

well you can have a claim for both sides but i’d go with true

Help me with this I keep getting it wrong apparently

Answers

Answer: Hello!

Explanation: The reason photosynthesis is beneficial towards people is because the process produces oxygen to breath. Hence A is correct.

Finn, tenth grade straight A student.

Have a great day!

Answer:

i think its Provide oxygen to breathe and provides carbon dioxide to do respiration with and im not sure if its either provides energy for food or provides ATP energy for our cells

Explanation:

sorry if i got this wrong

Which of the following affects recreational activities that people do in a region?
A.
soil type
B.
plants
C.
presence and quality of water
D.
oil

Answers

Answer:

A. Soil Type, B. Plants, and C. Presence and Quality of Water

Explanation:

A) Soil contains air, water, and minerals as well as plant and animal matter, both living and dead, which is why it must be the first answer

B) Plant Elements include nitrogen, phosphorus, potassium, calcium, magnesium, sulfur, boron, chlorine, iron, manganese, zinc, copper, molybdenum, and nickel. It is used for photosynthesis

C) Do i really need to explain this one?

hat type(s) of hydrophilic amino acids would you expect to find in the transmembrane domain of the chloride channel?

Answers

This collection characteristic may be recognized in number one sequences the use of hydrophilic scales [7,8,9]. The maximum plentiful amino acids in transmembrane areas are leucine, isoleucine, valine, phenylalanine, alanine, glycine, serine, and threonine.

Six hydrophilic amino acids have facet chains which are polar however now no longer charged. These are serine (Ser), threonine (Thr), cysteine (Cys), asparagine (Asn), glutamine (Gln), and tyrosine (Tyr). These amino acids are commonly located on the floor of proteins, as mentioned withinside the Proteins 2 module.

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What is the weather like for after a stationary front?

Answers

Answer:

cloudy skies and prolonged precipitation can occur, with mesocyclone systems. When the warmer air mass is very humid, heavy or extreme precipitation can occur.

Explanation:

please help me im giving 15 points

Answers

Answer: Polymer

Explanation: It is made of alkenes joining together to form long complex compounds. The process is called polymerization.

in this question and your wider MYP knowledge, discuss and evaluate the possible implications of using light technology (Lasik).



In your answer, you should include:

-An evaluation on using light technology (Lasik)

-Economical impacts of introducing Lasik

-Social impacts of using Lasik

-A concluding recommendation based on the arguments you have discussed

Answers

It may give you some peace of mind to know that complications from LASIK are extremely unlikely to result in major, permanent vision loss.   Thus, option D is correct.

What are the implications of using light technology (Lasik)?

If you are considering the treatment but are concerned that anything might go wrong. Additionally, laser re-treatment can be used to fix a variety of issues.

Loss of vision as a result of complications is extremely uncommon. However, some LASIK side effects, notably dry eyes and transient vision issues like glare, are very typical.

Few people think these are long-term issues because they typically go away within a few weeks or months.

Therefore, A concluding recommendation based on the arguments you have discussed.

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The evolution of Drug-Resistance HIV. Within a few weeks of treatment with drug X, a patient's HIV population consists entirely of X-resistant HIV. Explain how this rapid evolution of drug resistance is an example of natural selection.

Answers

Bacteria can develop antibiotic resistance either by obtaining specific resistance genes from these other bacteria or by developing mutations that change the biological targets of antibiotics.

What does mutation entail?

a deviation from the typical DNA sequence at a certain gene locus. Although the phrase is frequently associated with negativity, mutations (including polymorphisms) may affect cell activity in ways that are negative, positive, or neutral.

What are the four mutation types?

Gametes experience germline mutations. Other bodily cells can develop somatic mutations. Mutations that modify the chromosome's structure are called chromosomal changes. A single nucleotide is altered by point mutations.

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Temperature, humidity, light and atmospheric pressure are

Answers

Answer:

Abiotic components of nature

Explanation:

Aboutic means those who cant breathe or move or are not alive

During DNA replication prior to meiosis, a frameshift mutation occurs. Will this mutation be inherited?

a
Yes, because meiosis makes exact cellular copies.
b
Yes, because frameshift mutations are always passed on to offspring.
c
Yes, because the error happened in a gamete.
d
Yes, because the error happened in a somatic cell.

Answers

Yes, a frameshift mutation that occurs during DNA replication prior to meiosis will be inherited because the error happened in a gamete; option C.

What is a mutation?

A mutation is a change that occurs in the sequence of nucleotides in a DNA molecule.

Mutations that are inheritable are those mutations that affect the gametes.

Gametes refer to the haploid cells that are produced during the process of meiosis. Gametes produce egg cells and sperm cells.

Therefore, a mutation that occurs prior to meiosis could be inherited because it will be present in the gametes.

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which type of nissl stain requires a fluorescent microscope (a light microscope is not sufficient to reveal results)

Answers

Neurotrace a type of NISSL stain requires a fluorescent microscope as a light microscope is not sufficient to reveal results.

A common histology technique for identifying neurons in the brain and spinal cord is Nissl staining. The Nissl substance, a marker for the physiological status of the neuron, redistributes inside the cell body in injured or regenerating neurons. It is made up of ribosomal RNA coupled with the rough endoplasmic reticulum in neuronal perikarya and dendrites. NeuroTrace 640/660 deep-red fluorescent Nissl stain is more sensitive than conventional histology dyes like toluidine blue or cresyl violet and is selective for the Nissl material that is distinctive of neurons.

A popular technique for examining the anatomy and pathophysiology of neural tissue is Nissl staining. The characteristic staining of the neuronal perikarya is either absent or has a very weak signal after standard immunocytochemistry, leaving only the nucleus of the neurons to be labeled.

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describe the mechanisms that ensure parental and daughter duplexes have identical DNA sequences

Answers

The mechanism that ensures parental and daughter duplexes have identical DNA sequences is the replication process. It occurs before cell division and provides each daughter cell with the same chromosomic set as the parental cell.

What is DNA replication?

DNA replication is a process through which DNA molecules are duplicated. It occurs during the S phase of the interphase, before cell division.

In the interphase the cell duplicates its content, so every daughter cell gets the same material. Hence, DNA must be replicated, so daughter cells have a complete chromosomic set.

DNI replication is semi-conservative because each new molecule carries an original DNI strand and a new one. The old existing strands are used to synthesize the new complementary strand.

To separate the original strands, helicase enzymes must act in the replication origin to break hydrogen bonds and separate the strands.

While the strands unroll, the topoisomerase enzyme releases tension.

Other proteins are also needed to join the strains and keep them separated.

Once the molecule is opened, there is a region named replication forks. DNA polymerase pairs new nucleotides with the corresponding nucleotide of the original strand.

DNA strands are antiparallel, and replication occurs only in 5'-3' direction. One of the strands is continuously replicated, while the other strain grows in short Okazaki fragments.

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lymphatic organs differ from lymphatic tissues in what way? a) they contain t lymphocytes and lymphatic tissues do not. b) they are found in the digestive tract and lymphatic tissues are found in the thorax. c) they are surrounded by a fibrous capsule and lymphatic tissues are not. d) they cannot produce antibodies, whereas lymphatic tissues can. e) they occur throughout the body except in the head.

Answers

Lymphatic organs differ from lymphatic tissues in following way:

e) that they occur throughout the body except in head.

How does lymphatic organs differ from lymphatic tissues?

Lymphatic organs occur throughout the body except in the head. They are surrounded by a fibrous capsule but lymphatic tissues are not. They also have T lymphocytes and lymphatic tissues do not.

Lymphatic system contains the bone marrow, spleen, thymus, lymph nodes and lymphatic vessels. The lymphatic system is an organ system that is part of the immune system and complementary to the circulatory system.

Lymphoid tissues are organized structures that support immune responses and  bone marrow and thymus are primary lymphoid tissues and the sites of lymphocyte development.

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you are observing a population of sea urchins experiencing logistic growth. what is the carrying capacity (k)?

Answers

A typical echinoderm boat is 20 to 30 feet long and can carry 2,000 to 6,000 pounds.

In logistic growth, a population's rate of per capita growth declines because it approaches the carrying capacity, a limit imposed by the environment's finite resources ( K).

What about sea urchins?You may suffer major health effects if your injury is severe or if you do not properly treat it. Echinoderm stings can result in tissue necrosis, death, paralysis, and respiratory failure. Skin cells that do not receive enough oxygen or blood perish and cause tissue necrosis. Echinoderm stings hurt right away. They often create puncture wounds on the skin, which if not treated immediately can quickly become infections. The sting site may swell and switch crimson. If the skin is penetrated (which happens frequently), the puncture site is usually bruised and appears blue-black. Echinoderm or uni because it is more generally known by its Japanese name, are often eaten in a variety of ways, including as a savoury complement to pasta dishes and as a part of a sushi feast. The buttery flavour and (pleasantly) slimy texture of uni, however, are best experienced fresh from the shell. Echinoderm has a little saltiness without being too salty. Once they are fresh, they ought to have a sweet, saltwater flavor and taste of iron and zinc. Uni features a strong mineral and seaweed flavor and ought to have a creamy texture. Older ones taste quite harsh and have a slimy texture on the tongue.

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each chamber of the heart has a particular role in maintaining cellular oxygenation. which chamber is responsible for receiving oxygenated blood from the lungs?

Answers

Blood that is rich in oxygen is drawn from the lungs and pumped to the left ventricle by the left atrium.

The heart has two atria and two ventricles, making up its four chambers. Blood with low oxygen content is drawn from the body and pumped to the right ventricle via the right atrium. The blood with less oxygen is sent to the lungs via the right ventricle. Blood that is rich in oxygen is drawn from the lungs and pumped to the left ventricle by the left atrium.

What about human heart?A fist-sized organ, the heart circulates blood throughout your body. It serves as your circulatory system's main organ. Four major muscle-driven chambers make up your heart; they are each powered by electrical impulses. Your nerve system and brain control how your heart beats. A little to the left of centre, in the chest, is the heart. It is located between the lungs and behind the breastbone.There are four different chambers in the heart. The left and right ventricles are located at the bottom, whereas the left and right atria are located at the top. The heart is made up of four chambers in humans, other mammals, and birds: upper left and right atria and bottom left and right ventricles. The right atrium and ventricle are frequently referred to as the right heart and its left counterparts as the left heart. According to Gray's Anatomy, the heart measures 12 cm in length, 8.5 cm in width, and 6 cm in thickness. Additionally, the average weight of the heart is 230-280 g for women and 280-340 g for men.

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Individual bones within the spinal column are called:

A) Vertebrae
B) Ganglia

Answers

Answer:

The answer is A) Vertebrae

Ganglia is incorrect because they are clusters of nerve cell bodies

The individual bones within the spinal column is called the Vertebrae.

can the biological species concept be applied to organisms that reproduce both asexually and sexually

Answers

The concept of biological species does not apply to asexual organisms.

The concept is dependent on interbreeding on diverse species , the concept cannot be applied on asexual organism because their reproduction takes place as a result of mutation in their DNA.

Biological species concept defines a species as members of populations that actually or potentially interbreed in nature, not dependent on similarity or appearance. Their  appearance  are useful in identifying species, but it does not define species. On the other hand A single biological species concept based on gene flow is applicable to all cellular form of life .

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how can you increase system efficiency

Answers

You increase system efficiency to create the smooth running system

The energy efficiency of a system or device that convert energy is measured by the ratio of the amount of useful energy put out by the system means output energy to the total amount of energy that is put in means input energy by useful output energy as a percentage of the total input energy allow you to achieve more with less get things done in less time and allow you to scale your operation

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which neurotransmitters are excitatory to some cells and inhibitory to others, depending on the type of receptors on the target cells? multiple select question. gaba acetylcholine glycine norepinephrine glutamate

Answers

The neurotransmitters are excitatory to some cells and inhibitory to others, depending on the type of receptors on the target cells are acetylcholine and norepinephrine.

A molecule that, when a nerve impulse arrives, is released at the end of a nerve fiber. This chemical then diffuses across the synapse or junction, causing the impulse to be transferred to another nerve fiber, a muscle fiber, or some other structure is called neurotransmitter.

Depending on the type of receptors present, some neurotransmitters, like acetylcholine and norepinephrine, can have both excitatory and inhibitory effects. When several synapses in close proximity are triggered at once or receive input from several presynaptic cells, spatial summation occurs.

Thus, because of receptors these can cause excitatory as well as inhibitory responses by summation of impulses.

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duchenne muscular dystrophy is caused by a sex-linked recessive allele. its victims are almost invariably boys, who usually die before the age of 20. why is this disorder almost never seen in girls?

Answers

Duchenne muscular dystrophy is almost never seen in girls because girls hаve two X chromosomes аnd hence need two copies of the аffected gene to cаuse the disorder.

What is Duchenne muscular dystrophy?

Duchenne musculаr dystrophy is а X-linked recessive disorder. The аssociаted genes аre locаted on the X chromosome, which is one of the two sex chromosomes. Since boys аre hemizygous for chromosome (hаve only one X chromosome), one copy of the аffected gene in eаch cell is sufficient to cаuse the disorder. GIrls hаve two X chromosomes аnd hence need two copies of the аffected gene to cаuse the disorder. Girls heterozygous for this trаit be normаl but serve аs а cаrrier of the diseаse. Since the frequency of girls with two аltered copies of this gene, boys аre аffected by this disorder much more frequently thаn girls. Duchenne musculаr dystrophy is never pаssed from fаther to sons becаuse fаthers cаnnot pаss X-linked trаits to their sons. Thus, Duchenne musculаr dystrophy is а sex-linked diseаse, not аn аutosomаl trаit which is pаssed to both sexes with equаl frequency.

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A soft drink manufacturer has a daily production cost of C = 70,000 - 120x + 0.055x ^ 2 , where C is the total cost (in dollars) and x is the number of units produced. How many units should they produce each day to yield a minimum cost? Show all work please. 1. Which of the following best identifies the historical development thatDefoe describes in this passage?(A) The emergence of the cottage industry system in Western Europe(B) The spread of mixed farming that increased agricultural productivity(C) The migration of people to towns for jobs caused by the enclosuremovement(D) The use of new technology that created more jobs in textile factoriesS A student noticed that placing wilted lettuce in a bowl of cool water caused the lettuce to become more crisp and firm. What is the best explanation for his observation?. How many particles are in 0.75 moles of AgNO3? 125 in the ratio 2:3 Hannah swims in a swimming pool of 25 metres long.How many laps does she need to complete for a total distance of 0.5 kilometre? A movie theater showed an old, classic movie on Saturday and Sunday. Tickets cost c dollars for children under the age of 13 and d dollars for others.On Saturday they sold 84 children's tickets and 157 tickets for others and collected $2,640 from ticket sales. On Sunday they sold 67 children's tickets and 134 other tickets and collected $2,211 from ticket sales. This can be represented by this system of equations 84c + 157d = 2,64067c + 134d = 2,211A. What could the equation 17c + 23d = 429 mean in this situation? B. The solution to the original system is the pair c = 9 and d = 12. Explain why it makes sense that thispair of values is also a solution to the equation 17c + 23d = 429. What does the veto power allow the governor to do?O name agenciesO appoint a judgeO eject a lawO call a legislative session 4. This time tomorrow I (fly) to France. 17. What are the main qualifications to vote in New Mexico? (select all that apply) *18 years old or olderUnited States citizenNew Mexico residentmust be mentally competentnot serving a sentence for a felony Which of the following is not a trait of romance literature?Ochivalrysupernatural elementsphysical attractiona quest how would the experimental molecular weight be affected if a few drops of the titrant were stuck on the inside wall of the flask during the titration and not rinsed into the solution? Find the variables in the figure (x and y) please and thank you!! what's the distance between points A and B A line with a slope of 5 passes through the points (7,2) and (8,q). What is the value of q? Identify and explain where in the region these would be found. perma frost nour's responsibilities include creating organizational goals and overall strategy for the organization. in terms of her level in the organization, which type of manager is nour what challenge is often experienced when employees make the transition from hourly worker to supervisor? Write a 7 sentence paragraph with evidence from the text to show what happened to the African tribes and residents when the scramble for Africa took place Find the measure of the exterior angle.